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These reference sequences exist independently of genome builds. Explain
These reference sequences are curated independently of the genome
annotation cycle, so their versions may not match the RefSeq versions in the current
genome build. Identify version mismatches by comparing the version of the RefSeq in
this section to the one reported in Genomic regions,
transcripts, and products above.
Genomic
-
NG_016850.2 RefSeqGene
- Range
-
5002..25749
- Download
- GenBank, FASTA, Sequence Viewer (Graphics)
mRNA and Protein(s)
-
NM_001194946.2 → NP_001181875.2 eukaryotic translation initiation factor 4 gamma 1 isoform 6
Status: REVIEWED
- Description
- Transcript Variant: This variant (6) differs in the 5' UTR, includes an additional in-frame exon in the 5' coding region, and uses an alternate in-frame splice site in the central coding region, compared to variant 1. The resulting isoform (6) is longer than isoform 1. Both variants 6 and 7 encode the same isoform.
- Source sequence(s)
-
AC078797
- Consensus CDS
-
CCDS54687.1
- UniProtKB/TrEMBL
-
B2RU10
- Related
- ENSP00000371767.3, ENST00000382330.7
- Conserved Domains (4) summary
-
- cd11559
Location:1445 → 1577
- W2_eIF4G1_like; C-terminal W2 domain of eukaryotic translation initiation factor 4 gamma 1 and similar proteins
- PHA03247
Location:21 → 583
- PHA03247; large tegument protein UL36; Provisional
- pfam02847
Location:1249 → 1361
- MA3; MA3 domain
- pfam02854
Location:768 → 993
- MIF4G; MIF4G domain
-
NM_001194947.2 → NP_001181876.2 eukaryotic translation initiation factor 4 gamma 1 isoform 6
Status: REVIEWED
- Description
- Transcript Variant: This variant (7) differs in the 5' UTR, includes an additional in-frame exon in the 5' coding region, and uses an alternate in-frame splice site in the central coding region, compared to variant 1. The resulting isoform (6) is longer than isoform 1. Both variants 6 and 7 encode the same isoform.
- Source sequence(s)
-
AC078797
- Consensus CDS
-
CCDS54687.1
- UniProtKB/TrEMBL
-
B2RU10
- Related
- ENSP00000338020.4, ENST00000352767.7
- Conserved Domains (4) summary
-
- cd11559
Location:1445 → 1577
- W2_eIF4G1_like; C-terminal W2 domain of eukaryotic translation initiation factor 4 gamma 1 and similar proteins
- PHA03247
Location:21 → 583
- PHA03247; large tegument protein UL36; Provisional
- pfam02847
Location:1249 → 1361
- MA3; MA3 domain
- pfam02854
Location:768 → 993
- MIF4G; MIF4G domain
-
NM_001291157.2 → NP_001278086.2 eukaryotic translation initiation factor 4 gamma 1 isoform 7
Status: REVIEWED
- Description
- Transcript Variant: This variant (8) differs in the 5' UTR, includes an additional internal segment in the 5' region, which results in a downstream start codon, and uses an alternate in-frame splice site in the central coding region, compared to variant 1. The resulting isoform (7) is shorter at the N-terminus, and lacks an internal residue, compared to isoform 1.
- Source sequence(s)
-
AC078797
- Consensus CDS
-
CCDS77866.1
- UniProtKB/TrEMBL
-
E7EUU4
- Related
- ENSP00000391935.1, ENST00000414031.5
- Conserved Domains (4) summary
-
- cd11559
Location:1398 → 1530
- W2_eIF4G1_like; C-terminal W2 domain of eukaryotic translation initiation factor 4 gamma 1 and similar proteins
- PHA03247
Location:13 → 536
- PHA03247; large tegument protein UL36; Provisional
- pfam02847
Location:1202 → 1314
- MA3; MA3 domain
- pfam02854
Location:721 → 949
- MIF4G; MIF4G domain
-
NM_004953.5 → NP_004944.3 eukaryotic translation initiation factor 4 gamma 1 isoform 4
Status: REVIEWED
- Description
- Transcript Variant: This variant (5) differs in the 5' UTR, lacks a portion of the 5' coding region, and uses a downstream start codon, compared to variant 1. The resulting isoform (4) is shorter at the N-terminus, compared to isoform 1.
- Source sequence(s)
-
AC078797, BQ011010
- Consensus CDS
-
CCDS46970.2
- UniProtKB/TrEMBL
-
E7EX73
- Related
- ENSP00000411826.2, ENST00000434061.6
- Conserved Domains (4) summary
-
- cd11559
Location:1243 → 1375
- W2_eIF4G1_like; C-terminal W2 domain of eukaryotic translation initiation factor 4 gamma 1 and similar proteins
- pfam02847
Location:1047 → 1159
- MA3; MA3 domain
- pfam02854
Location:566 → 791
- MIF4G; MIF4G domain
- pfam08648
Location:952 → 1053
- DUF1777; Protein of unknown function (DUF1777)
-
NM_182917.4 → NP_886553.3 eukaryotic translation initiation factor 4 gamma 1 isoform 1
Status: REVIEWED
- Description
- Transcript Variant: This variant (1) represents the longest transcript and encodes isoform 1.
- Source sequence(s)
-
AF002815, AK308319, AY082886, BQ011010, DC347118
- Consensus CDS
-
CCDS54688.1
- UniProtKB/TrEMBL
-
B2RU10
- Related
- ENSP00000343450.4, ENST00000342981.8
- Conserved Domains (4) summary
-
- cd11559
Location:1439 → 1571
- W2_eIF4G1_like; C-terminal W2 domain of eukaryotic translation initiation factor 4 gamma 1 and similar proteins
- pfam02847
Location:1243 → 1355
- MA3; MA3 domain
- pfam02854
Location:762 → 987
- MIF4G; MIF4G domain
- pfam08648
Location:1148 → 1249
- DUF1777; Protein of unknown function (DUF1777)
-
NM_198241.3 → NP_937884.2 eukaryotic translation initiation factor 4 gamma 1 isoform 5
Status: REVIEWED
- Description
- Transcript Variant: This variant (2) differs in the 5' UTR and uses an alternate in-frame splice site in the central coding region, compared to variant 1, resulting in an isoform (5) that is 1 aa shorter than isoform 1.
- Source sequence(s)
-
AC078797
- Consensus CDS
-
CCDS3259.1
- UniProtKB/Swiss-Prot
- D3DNT2, D3DNT4, D3DNT5, E9PFM1, G5E9S1, O43177, O95066, Q04637, Q5HYG0, Q6ZN21, Q8N102
- UniProtKB/TrEMBL
-
B2RU10
- Related
- ENSP00000316879.5, ENST00000346169.7
- Conserved Domains (5) summary
-
- cd11559
Location:1438 → 1570
- W2_eIF4G1_like; C-terminal W2 domain of eukaryotic translation initiation factor 4 gamma 1 and similar proteins
- PHA03247
Location:20 → 452
- PHA03247; large tegument protein UL36; Provisional
- PRK12323
Location:405 → 573
- PRK12323; DNA polymerase III subunit gamma/tau
- pfam02847
Location:1242 → 1354
- MA3; MA3 domain
- pfam02854
Location:761 → 986
- MIF4G; MIF4G domain
-
NM_198242.3 → NP_937885.1 eukaryotic translation initiation factor 4 gamma 1 isoform 3
Status: REVIEWED
- Description
- Transcript Variant: This variant (4) differs in the 5' UTR, lacks a portion of the 5' coding region, uses a downstream start codon, and uses an alternate in-frame splice site in the central coding region, compared to variant 1. The resulting isoform (3) is shorter at the N-terminus and lacks an internal residue, compared to isoform 1.
- Source sequence(s)
-
AC078797
- Consensus CDS
-
CCDS3261.1
- UniProtKB/TrEMBL
-
E7EX73
- Related
- ENSP00000317600.8, ENST00000350481.9
- Conserved Domains (4) summary
-
- cd11559
Location:1274 → 1406
- W2_eIF4G1_like; C-terminal W2 domain of eukaryotic translation initiation factor 4 gamma 1 and similar proteins
- pfam02847
Location:1078 → 1190
- MA3; MA3 domain
- pfam02854
Location:597 → 822
- MIF4G; MIF4G domain
- pfam08648
Location:983 → 1084
- DUF1777; Protein of unknown function (DUF1777)
-
NM_198244.3 → NP_937887.2 eukaryotic translation initiation factor 4 gamma 1 isoform 2
Status: REVIEWED
- Description
- Transcript Variant: This variant (3) differs in the 5' UTR, lacks a portion of the 5' coding region, uses a downstream start codon, and uses an alternate in-frame splice site in the central coding region, compared to variant 1. The resulting isoform (2) is shorter at the N-terminus and lacks an internal residue, compared to isoform 1.
- Source sequence(s)
-
AC078797
- Consensus CDS
-
CCDS3260.1
- UniProtKB/TrEMBL
-
E9PGM1
- Related
- ENSP00000376320.2, ENST00000392537.6
- Conserved Domains (4) summary
-
- cd11559
Location:1351 → 1483
- W2_eIF4G1_like; C-terminal W2 domain of eukaryotic translation initiation factor 4 gamma 1 and similar proteins
- PHA03247
Location:28 → 489
- PHA03247; large tegument protein UL36; Provisional
- pfam02847
Location:1155 → 1267
- MA3; MA3 domain
- pfam02854
Location:674 → 902
- MIF4G; MIF4G domain
The following sections contain reference sequences that belong to a
specific genome build. Explain
This section includes genomic Reference
Sequences (RefSeqs) from all assemblies on which this gene is annotated, such as
RefSeqs for chromosomes and scaffolds (contigs) from both reference and alternate
assemblies. Model RNAs and proteins are also reported here.
Reference GRCh38.p14 Primary Assembly
Genomic
-
NC_000003.12 Reference GRCh38.p14 Primary Assembly
- Range
-
184314606..184335358
- Download
- GenBank, FASTA, Sequence Viewer (Graphics)
Alternate T2T-CHM13v2.0
Genomic
-
NC_060927.1 Alternate T2T-CHM13v2.0
- Range
-
187123882..187144618
- Download
- GenBank, FASTA, Sequence Viewer (Graphics)