Rmrp RNA component of mitochondrial RNAase P [Mus musculus (house mouse)] - Gene

Summary

Official Symbol: Rmrpprovided by MGI
Official Full Name: RNA component of mitochondrial RNAase Pprovided by MGI
Primary source: MGI:MGI:97937
See related: Ensembl:ENSMUSG00000088088 AllianceGenome:MGI:97937
Gene type: ncRNA
RefSeq status: PROVISIONAL
Organism: Mus musculus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as: Rmrpr; 1110032O22Rik
Summary: Acts upstream of or within in utero embryonic development. Is expressed in early conceptus and secondary oocyte. Human ortholog(s) of this gene implicated in anauxetic dysplasia 1 and cartilage-hair hypoplasia. Orthologous to human RMRP (RNA component of mitochondrial RNA processing endoribonuclease). [provided by Alliance of Genome Resources, Apr 2025]
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Genomic context

Location:: 4 A5; 4 23.04 cM

Exon count:: 1

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCm39 (GCF_000001635.27)	4	NC_000070.7 (43492785..43493059, complement)
108.20200622	previous assembly	GRCm38.p6 (GCF_000001635.26)	4	NC_000070.6 (43492785..43493059, complement)

Chromosome 4 - NC_000070.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Knockdown of long non-coding RNA RMRP protects cerebral ischemia-reperfusion injury via the microRNA-613/ATG3 axis and the JAK2/STAT3 pathway.
Title: Knockdown of long non-coding RNA RMRP protects cerebral ischemia-reperfusion injury via the microRNA-613/ATG3 axis and the JAK2/STAT3 pathway.
RMRP RNA expression is regulated during different stages of chondrogenic differentiation and indicate that RMRP RNA may play a pivotal role in chondrocyte hypertrophy.
Title: Expression of RMRP RNA is regulated in chondrocyte hypertrophy and determines chondrogenic differentiation.

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Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics (MGI)

Endonuclease-mediated (2)
Targeted (2) 1 citation

General gene information

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Markers

Rmrp (e-PCR), detects polymorphism
- UniSTS:496728

Other Names

RNA component of mitochondrial RNAase P, 1
RNase MRP

Gene Ontology Provided by MGI

Function	Evidence Code	Pubs
enables molecular_function	ND No biological Data available more info

Process	Evidence Code	Pubs
acts_upstream_of_or_within in utero embryonic development	IMP Inferred from Mutant Phenotype more info	PubMed

Component	Evidence Code	Pubs
is_active_in cellular_component	ND No biological Data available more info

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.