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Rgs5 regulator of G-protein signaling 5 [ Mus musculus (house mouse) ]

Gene ID: 19737, updated on 25-May-2017
Official Symbol
Rgs5provided by MGI
Official Full Name
regulator of G-protein signaling 5provided by MGI
Primary source
MGI:MGI:1098434
See related
Ensembl:ENSMUSG00000026678 Vega:OTTMUSG00000020901
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
1110070A02Rik
Orthologs
Location:
1 H2.3; 1 76.84 cM
Exon count:
6
Annotation release Status Assembly Chr Location
106 current GRCm38.p4 (GCF_000001635.24) 1 NC_000067.6 (169655501..169695813)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 1 NC_000067.5 (171585632..171623657)

Chromosome 1 - NC_000067.6Genomic Context describing neighboring genes Neighboring gene predicted gene, 34624 Neighboring gene predicted gene, 18900 Neighboring gene predicted gene, 39698 Neighboring gene regulator of G-protein signaling 4

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

  • Calcium Regulation in the Cardiac Cell, organism-specific biosystem (from WikiPathways)
    Calcium Regulation in the Cardiac Cell, organism-specific biosystemCalcium is a common signaling mechanism, as once it enters the cytoplasm it exerts allosteric regulatory affects on many enzymes and proteins. Calcium can act in signal transduction after influx resu...
  • Myometrial Relaxation and Contraction Pathways, organism-specific biosystem (from WikiPathways)
    Myometrial Relaxation and Contraction Pathways, organism-specific biosystemThis pathway illustrates signaling networks implicated in uterine muscle contraction at labor and quiescence throughout gestation (pregnancy). The muscle of the uterus, responsible for contractile ac...

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
GTPase activator activity TAS
Traceable Author Statement
more info
PubMed 
Process Evidence Code Pubs
G-protein coupled receptor signaling pathway TAS
Traceable Author Statement
more info
PubMed 
negative regulation of G-protein coupled receptor protein signaling pathway ISO
Inferred from Sequence Orthology
more info
 
negative regulation of signal transduction IEA
Inferred from Electronic Annotation
more info
 
signal transduction ISO
Inferred from Sequence Orthology
more info
 
Component Evidence Code Pubs
cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
 
cytosol ISO
Inferred from Sequence Orthology
more info
 
membrane IEA
Inferred from Electronic Annotation
more info
 
plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
 
Preferred Names
regulator of G-protein signaling 5

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001313705.1NP_001300634.1  regulator of G-protein signaling 5 isoform 2

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) differs in the 3' coding region and 3' UTR compared to variant 1. The encoded isoform (2) has a shorter, distinct C-terminus compared to isoform 1.
    Source sequence(s)
    AC115766, AC117808
    Consensus CDS
    CCDS83629.1
    UniProtKB/TrEMBL
    A0A0A6YWD0
    Related
    ENSMUSP00000141496.1, OTTMUSP00000068653, ENSMUST00000152809.2, OTTMUST00000049407
  2. NM_009063.4NP_033089.2  regulator of G-protein signaling 5 isoform 1

    See identical proteins and their annotated locations for NP_033089.2

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1).
    Source sequence(s)
    AC115766, AK054098
    Consensus CDS
    CCDS15464.1
    UniProtKB/Swiss-Prot
    O08850
    Related
    ENSMUSP00000027997.3, OTTMUSP00000022882, ENSMUST00000027997.8, OTTMUST00000049406
    Conserved Domains (1) summary
    cd08717
    Location:65178
    RGS_RGS5; Regulator of G protein signaling (RGS) domain found in the RGS5 protein

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm38.p4 C57BL/6J

Genomic

  1. NC_000067.6 Reference GRCm38.p4 C57BL/6J

    Range
    169655501..169695813
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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