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WDR90 WD repeat domain 90 [ Homo sapiens (human) ]

Gene ID: 197335, updated on 17-May-2020

Summary

Official Symbol
WDR90provided by HGNC
Official Full Name
WD repeat domain 90provided by HGNC
Primary source
HGNC:HGNC:26960
See related
Ensembl:ENSG00000161996 MIM:618290
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
POC16; C16orf15; C16orf16; C16orf17; C16orf18; C16orf19
Expression
Broad expression in testis (RPKM 12.0), bone marrow (RPKM 4.3) and 23 other tissues See more
Orthologs

Genomic context

See WDR90 in Genome Data Viewer
Location:
16p13.3
Exon count:
42
Annotation release Status Assembly Chr Location
109.20200228 current GRCh38.p13 (GCF_000001405.39) 16 NC_000016.10 (649363..667833)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 16 NC_000016.9 (699363..717833)

Chromosome 16 - NC_000016.10Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC100287175 Neighboring gene MAPK regulated corepressor interacting protein 2 Neighboring gene uncharacterized LOC105371038 Neighboring gene uncharacterized LOC107984861 Neighboring gene ras homolog family member T2 Neighboring gene rhomboid like 1

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

Phenotypes

NHGRI GWAS Catalog

Description
Genome-wide association analysis of red blood cell traits in African Americans: the COGENT Network.
NHGRI GWA Catalog

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • FLJ36483, FLJ44660, KIAA1924

Gene Ontology Provided by GOA

Function Evidence Code Pubs
microtubule binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Process Evidence Code Pubs
cilium assembly IMP
Inferred from Mutant Phenotype
more info
PubMed 
Component Evidence Code Pubs
centriole IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
centriole IDA
Inferred from Direct Assay
more info
PubMed 
cytoplasm IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
WD repeat-containing protein 90

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_145294.5NP_660337.3  WD repeat-containing protein 90

    See identical proteins and their annotated locations for NP_660337.3

    Status: VALIDATED

    Source sequence(s)
    AB067511, AK091062, AK092719, AK126622, Z92544
    Consensus CDS
    CCDS42092.1
    UniProtKB/Swiss-Prot
    Q96KV7
    Related
    ENSP00000293879.4, ENST00000293879.9
    Conserved Domains (4) summary
    COG2319
    Location:11551549
    WD40; WD40 repeat [General function prediction only]
    pfam05018
    Location:5181
    DUF667; Protein of unknown function (DUF667)
    sd00039
    Location:13921433
    7WD40; WD40 repeat [structural motif]
    cl02567
    Location:697991
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000016.10 Reference GRCh38.p13 Primary Assembly

    Range
    649363..667833
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_017023023.1XP_016878512.1  WD repeat-containing protein 90 isoform X1

  2. XM_017023024.1XP_016878513.1  WD repeat-containing protein 90 isoform X2

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

  1. NM_153239.2: Suppressed sequence

    Description
    NM_153239.2: This RefSeq was permanently suppressed because it is a nonsense-mediated mRNA decay (NMD) candidate.
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