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Bex1 brain expressed X-linked 1 [ Mus musculus (house mouse) ]

Gene ID: 19716, updated on 8-Nov-2022

Summary

Official Symbol
Bex1provided by MGI
Official Full Name
brain expressed X-linked 1provided by MGI
Primary source
MGI:MGI:1328321
See related
Ensembl:ENSMUSG00000050071 AllianceGenome:MGI:1328321
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Bex2; Bex4; Rex3
Summary
Predicted to enable signaling receptor binding activity. Acts upstream of or within axon regeneration. Located in cytoplasm and nucleus. Is expressed in several structures, including early conceptus; ganglia; gonad; gut; and lung. Orthologous to human BEX2 (brain expressed X-linked 2). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in placenta adult (RPKM 230.0), liver E14 (RPKM 115.8) and 10 other tissues See more
Orthologs
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Genomic context

See Bex1 in Genome Data Viewer
Location:
X F1; X 57.4 cM
Exon count:
3
Annotation release Status Assembly Chr Location
109 current GRCm39 (GCF_000001635.27) X NC_000086.8 (135114721..135116262, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) X NC_000086.7 (136213972..136215513, complement)

Chromosome X - NC_000086.8Genomic Context describing neighboring genes Neighboring gene predicted gene, 41901 Neighboring gene nuclear encoded tRNA lysine 19 (anticodon CTT) Neighboring gene transcription elongation factor A (SII)-like 5 Neighboring gene predicted gene, 51612 Neighboring gene transcription elongation factor A (SII)-like 7 Neighboring gene predicted gene, 39535

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • MGC107097

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables RNA polymerase II-specific DNA-binding transcription factor binding ISO
Inferred from Sequence Orthology
more info
 
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
enables signaling receptor binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Component Evidence Code Pubs
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in cytoplasm IDA
Inferred from Direct Assay
more info
PubMed 
located_in cytoplasm ISO
Inferred from Sequence Orthology
more info
 
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in nucleus IDA
Inferred from Direct Assay
more info
PubMed 
located_in nucleus ISO
Inferred from Sequence Orthology
more info
PubMed 
part_of transcription regulator complex ISO
Inferred from Sequence Orthology
more info
 

General protein information

Preferred Names
protein BEX2
Names
REX-3
brain expressed gene 1
brain-expressed X-linked protein 1 homolog
brain-expressed X-linked protein 2 homolog
protein BEX1
reduced expression 3
reduced expression protein 3

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_009052.2NP_033078.2  protein BEX2

    See identical proteins and their annotated locations for NP_033078.2

    Status: VALIDATED

    Source sequence(s)
    AF097438, BY115963, CB194115
    Consensus CDS
    CCDS30417.1
    UniProtKB/Swiss-Prot
    Q9R1J2, Q9R224
    Related
    ENSMUSP00000060005.9, ENSMUST00000058125.9
    Conserved Domains (1) summary
    pfam04538
    Location:13124
    BEX; Brain expressed X-linked like family

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000086.8 Reference GRCm39 C57BL/6J

    Range
    135114721..135116262 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)