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Rbpj recombination signal binding protein for immunoglobulin kappa J region [ Mus musculus (house mouse) ]

Gene ID: 19664, updated on 27-Feb-2024

Summary

Official Symbol
Rbpjprovided by MGI
Official Full Name
recombination signal binding protein for immunoglobulin kappa J regionprovided by MGI
Primary source
MGI:MGI:96522
See related
Ensembl:ENSMUSG00000039191 AllianceGenome:MGI:96522
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
CBF1; RBP-J; RBPjk; Igkjrb; Rbpsuh; Igkrsbp; RBP-Jkappa; RBP-J kappa
Summary
Enables several functions, including DNA-binding transcription activator activity, RNA polymerase II-specific; RNA polymerase II cis-regulatory region sequence-specific DNA binding activity; and protein N-terminus binding activity. Involved in several processes, including circulatory system development; positive regulation of signal transduction; and regulation of transcription by RNA polymerase II. Acts upstream of or within several processes, including animal organ development; blood vessel morphogenesis; and regulation of transcription, DNA-templated. Located in nucleus. Part of transcription regulator complex. Is expressed in several structures, including early conceptus; genitourinary system; neural ectoderm; paraxial mesenchyme; and retina. Used to study aortic valve disease. Human ortholog(s) of this gene implicated in Adams-Oliver syndrome and dilated cardiomyopathy. Orthologous to human RBPJ (recombination signal binding protein for immunoglobulin kappa J region). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in limb E14.5 (RPKM 12.9), CNS E11.5 (RPKM 12.5) and 28 other tissues See more
Orthologs
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

See Rbpj in Genome Data Viewer
Location:
5 C1; 5 29.37 cM
Exon count:
17
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 5 NC_000071.7 (53713121..53814787)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 5 NC_000071.6 (53555779..53657445)

Chromosome 5 - NC_000071.7Genomic Context describing neighboring genes Neighboring gene STARR-seq mESC enhancer starr_13084 Neighboring gene predicted gene 10441 Neighboring gene STARR-seq mESC enhancer starr_13086 Neighboring gene STARR-seq mESC enhancer starr_13089 Neighboring gene predicted gene, 40304 Neighboring gene STARR-seq mESC enhancer starr_13090 Neighboring gene CapStarr-seq enhancer MGSCv37_chr5:53980216-53980325 Neighboring gene STARR-seq mESC enhancer starr_13092 Neighboring gene STARR-seq mESC enhancer starr_13095 Neighboring gene cholecystokinin A receptor Neighboring gene TBC1 domain family, member 19

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Targeted (8)  1 citation
  • Endonuclease-mediated (9) 

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables DNA binding IDA
Inferred from Direct Assay
more info
PubMed 
enables DNA binding ISO
Inferred from Sequence Orthology
more info
PubMed 
enables DNA-binding transcription activator activity, RNA polymerase II-specific IDA
Inferred from Direct Assay
more info
PubMed 
enables DNA-binding transcription activator activity, RNA polymerase II-specific ISO
Inferred from Sequence Orthology
more info
PubMed 
enables DNA-binding transcription factor activity IEA
Inferred from Electronic Annotation
more info
 
enables DNA-binding transcription factor activity, RNA polymerase II-specific IBA
Inferred from Biological aspect of Ancestor
more info
 
enables DNA-binding transcription factor binding ISO
Inferred from Sequence Orthology
more info
 
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IBA
Inferred from Biological aspect of Ancestor
more info
 
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IDA
Inferred from Direct Assay
more info
PubMed 
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding ISO
Inferred from Sequence Orthology
more info
 
enables RNA polymerase II-specific DNA-binding transcription factor binding ISO
Inferred from Sequence Orthology
more info
 
enables chromatin binding IDA
Inferred from Direct Assay
more info
PubMed 
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
enables protein-containing complex binding ISO
Inferred from Sequence Orthology
more info
 
enables sequence-specific DNA binding IDA
Inferred from Direct Assay
more info
PubMed 
enables sequence-specific DNA binding ISO
Inferred from Sequence Orthology
more info
 
Process Evidence Code Pubs
acts_upstream_of_or_within B cell differentiation IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in Notch signaling pathway IBA
Inferred from Biological aspect of Ancestor
more info
 
acts_upstream_of_or_within Notch signaling pathway IGI
Inferred from Genetic Interaction
more info
PubMed 
acts_upstream_of_or_within Notch signaling pathway IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in Notch signaling pathway IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in Notch signaling pathway ISO
Inferred from Sequence Orthology
more info
 
involved_in Notch signaling pathway TAS
Traceable Author Statement
more info
PubMed 
acts_upstream_of_or_within angiogenesis IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in aortic valve development IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in arterial endothelial cell fate commitment IMP
Inferred from Mutant Phenotype
more info
PubMed 
acts_upstream_of_or_within artery morphogenesis IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in atrioventricular canal development IMP
Inferred from Mutant Phenotype
more info
PubMed 
acts_upstream_of_or_within auditory receptor cell fate commitment IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in blood vessel endothelial cell fate specification IGI
Inferred from Genetic Interaction
more info
PubMed 
involved_in blood vessel lumenization IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in blood vessel remodeling IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in cardiac left ventricle morphogenesis IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in cardiac muscle cell myoblast differentiation IMP
Inferred from Mutant Phenotype
more info
PubMed 
acts_upstream_of cell differentiation IMP
Inferred from Mutant Phenotype
more info
PubMed 
acts_upstream_of_or_within cell fate commitment IMP
Inferred from Mutant Phenotype
more info
PubMed 
acts_upstream_of cell population proliferation IGI
Inferred from Genetic Interaction
more info
PubMed 
acts_upstream_of cell population proliferation IMP
Inferred from Mutant Phenotype
more info
PubMed 
acts_upstream_of_or_within club cell differentiation IMP
Inferred from Mutant Phenotype
more info
PubMed 
acts_upstream_of_or_within defense response to bacterium IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in determination of heart left/right asymmetry TAS
Traceable Author Statement
more info
PubMed 
involved_in dorsal aorta morphogenesis IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in endocardium development IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in endocardium morphogenesis IMP
Inferred from Mutant Phenotype
more info
PubMed 
acts_upstream_of_or_within epidermal cell fate specification IMP
Inferred from Mutant Phenotype
more info
PubMed 
acts_upstream_of epithelial cell proliferation IGI
Inferred from Genetic Interaction
more info
PubMed 
acts_upstream_of_or_within epithelial to mesenchymal transition IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in epithelial to mesenchymal transition involved in endocardial cushion formation IMP
Inferred from Mutant Phenotype
more info
PubMed 
acts_upstream_of_or_within hair follicle maturation IMP
Inferred from Mutant Phenotype
more info
PubMed 
acts_upstream_of_or_within heart development IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in heart development ISO
Inferred from Sequence Orthology
more info
 
involved_in heart induction TAS
Traceable Author Statement
more info
PubMed 
involved_in heart looping TAS
Traceable Author Statement
more info
PubMed 
acts_upstream_of_or_within hemopoiesis IMP
Inferred from Mutant Phenotype
more info
PubMed 
acts_upstream_of_or_within humoral immune response IMP
Inferred from Mutant Phenotype
more info
PubMed 
acts_upstream_of_or_within inflammatory response to antigenic stimulus IMP
Inferred from Mutant Phenotype
more info
PubMed 
acts_upstream_of_or_within interleukin-4 production IMP
Inferred from Mutant Phenotype
more info
PubMed 
acts_upstream_of_or_within keratinocyte differentiation IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in labyrinthine layer blood vessel development IMP
Inferred from Mutant Phenotype
more info
PubMed 
acts_upstream_of_or_within myeloid dendritic cell differentiation IMP
Inferred from Mutant Phenotype
more info
PubMed 
acts_upstream_of_or_within negative regulation of DNA-templated transcription IDA
Inferred from Direct Assay
more info
PubMed 
involved_in negative regulation of DNA-templated transcription ISO
Inferred from Sequence Orthology
more info
 
acts_upstream_of_or_within negative regulation of cell differentiation IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in negative regulation of cold-induced thermogenesis IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in negative regulation of ossification IMP
Inferred from Mutant Phenotype
more info
PubMed 
acts_upstream_of_or_within negative regulation of stem cell proliferation IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in negative regulation of transcription by RNA polymerase II IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in negative regulation of transcription by RNA polymerase II ISO
Inferred from Sequence Orthology
more info
 
acts_upstream_of_or_within neuron differentiation IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in outflow tract morphogenesis IMP
Inferred from Mutant Phenotype
more info
PubMed 
acts_upstream_of_or_within pituitary gland development IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in positive regulation of BMP signaling pathway IMP
Inferred from Mutant Phenotype
more info
PubMed 
acts_upstream_of_or_within positive regulation of DNA-templated transcription ISO
Inferred from Sequence Orthology
more info
PubMed 
involved_in positive regulation of ERBB signaling pathway IMP
Inferred from Mutant Phenotype
more info
PubMed 
acts_upstream_of_or_within positive regulation of canonical Wnt signaling pathway IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in positive regulation of cardiac muscle cell proliferation IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in positive regulation of cell proliferation involved in heart morphogenesis IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in positive regulation of ephrin receptor signaling pathway IMP
Inferred from Mutant Phenotype
more info
PubMed 
acts_upstream_of_or_within positive regulation of epithelial cell proliferation IGI
Inferred from Genetic Interaction
more info
PubMed 
acts_upstream_of_or_within positive regulation of gene expression IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in positive regulation of transcription by RNA polymerase II IDA
Inferred from Direct Assay
more info
PubMed 
involved_in positive regulation of transcription by RNA polymerase II IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in positive regulation of transcription by RNA polymerase II ISO
Inferred from Sequence Orthology
more info
 
acts_upstream_of_or_within positive regulation of transcription of Notch receptor target IGI
Inferred from Genetic Interaction
more info
PubMed 
involved_in positive regulation of transcription of Notch receptor target ISO
Inferred from Sequence Orthology
more info
 
involved_in pulmonary valve development IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in regulation of DNA-templated transcription IEA
Inferred from Electronic Annotation
more info
 
involved_in regulation of cell adhesion involved in heart morphogenesis IMP
Inferred from Mutant Phenotype
more info
PubMed 
acts_upstream_of_or_within regulation of epithelial cell proliferation IGI
Inferred from Genetic Interaction
more info
PubMed 
acts_upstream_of_or_within regulation of gene expression IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in regulation of generation of precursor metabolites and energy ISO
Inferred from Sequence Orthology
more info
 
acts_upstream_of_or_within regulation of reproductive process IGI
Inferred from Genetic Interaction
more info
PubMed 
acts_upstream_of_or_within regulation of timing of cell differentiation IMP
Inferred from Mutant Phenotype
more info
PubMed 
acts_upstream_of_or_within regulation of transcription by RNA polymerase II IGI
Inferred from Genetic Interaction
more info
PubMed 
involved_in regulation of transcription by RNA polymerase II IMP
Inferred from Mutant Phenotype
more info
PubMed 
acts_upstream_of_or_within sebaceous gland development IMP
Inferred from Mutant Phenotype
more info
PubMed 
acts_upstream_of_or_within secondary heart field specification IGI
Inferred from Genetic Interaction
more info
PubMed 
acts_upstream_of_or_within secondary heart field specification IMP
Inferred from Mutant Phenotype
more info
PubMed 
acts_upstream_of_or_within somatic stem cell population maintenance IMP
Inferred from Mutant Phenotype
more info
PubMed 
acts_upstream_of_or_within somitogenesis IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in somitogenesis TAS
Traceable Author Statement
more info
PubMed 
acts_upstream_of stem cell proliferation IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in ventricular septum morphogenesis IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in ventricular trabecula myocardium morphogenesis IMP
Inferred from Mutant Phenotype
more info
PubMed 
Component Evidence Code Pubs
part_of MAML1-RBP-Jkappa- ICN1 complex IBA
Inferred from Biological aspect of Ancestor
more info
 
part_of MAML1-RBP-Jkappa- ICN1 complex ISO
Inferred from Sequence Orthology
more info
 
located_in cytoplasm ISO
Inferred from Sequence Orthology
more info
 
located_in nucleolus ISO
Inferred from Sequence Orthology
more info
 
located_in nucleoplasm ISO
Inferred from Sequence Orthology
more info
 
located_in nucleoplasm TAS
Traceable Author Statement
more info
 
located_in nucleus IC
Inferred by Curator
more info
PubMed 
located_in nucleus IDA
Inferred from Direct Assay
more info
PubMed 
located_in nucleus ISO
Inferred from Sequence Orthology
more info
PubMed 
part_of protein-DNA complex ISO
Inferred from Sequence Orthology
more info
 
part_of protein-containing complex ISO
Inferred from Sequence Orthology
more info
 
part_of transcription regulator complex IDA
Inferred from Direct Assay
more info
PubMed 
part_of transcription repressor complex ISO
Inferred from Sequence Orthology
more info
 

General protein information

Preferred Names
recombining binding protein suppressor of hairless
Names
J-kappa recombination signal binding protein
Jkappa recombination signal binding protein

NCBI Reference Sequences (RefSeq)

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001080927.2NP_001074396.1  recombining binding protein suppressor of hairless isoform 2

    See identical proteins and their annotated locations for NP_001074396.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) differs in the 5' UTR, lacks a portion of the 5' coding region, and initiates translation at an alternate start codon, compared to variant 1. The encoded isoform (2) is shorter and has a distinct N-terminus, compared to isoform 1.
    Source sequence(s)
    AC084054, AK028363, AK080359, AK132145, BY716845
    Consensus CDS
    CCDS51504.1
    UniProtKB/TrEMBL
    Q3UM17
    Related
    ENSMUSP00000109496.2, ENSMUST00000113865.5
    Conserved Domains (3) summary
    cd01176
    Location:337433
    IPT_RBP-Jkappa; IPT domain of the recombination signal Jkappa binding protein (RBP-Jkappa). RBP-J kappa, was initially considered to be involved in V(D)J recombination because of its DNA binding specificity and structural similarity to site-specific recombinases known ...
    pfam09270
    Location:166315
    BTD; Beta-trefoil DNA-binding domain
    pfam09271
    Location:35164
    LAG1-DNAbind; LAG1, DNA binding
  2. NM_001080928.1NP_001074397.1  recombining binding protein suppressor of hairless isoform 3

    Status: VALIDATED

    Description
    Transcript Variant: This variant (3) differs in the 5' UTR, lacks a portion of the 5' coding region, and initiates translation at an alternate start codon, compared to variant 1. The encoded isoform (2) is shorter and has a distinct N-terminus, compared to isoform 1.
    Source sequence(s)
    AC084054, AK028363, AK132145, BB839243, CD540070
    Consensus CDS
    CCDS51503.1
    UniProtKB/TrEMBL
    E9Q7W0
    Related
    ENSMUSP00000084618.3, ENSMUST00000087360.9
    Conserved Domains (3) summary
    cd01176
    Location:335431
    IPT_RBP-Jkappa; IPT domain of the recombination signal Jkappa binding protein (RBP-Jkappa). RBP-J kappa, was initially considered to be involved in V(D)J recombination because of its DNA binding specificity and structural similarity to site-specific recombinases known ...
    pfam09270
    Location:164313
    BTD; Beta-trefoil DNA-binding domain
    pfam09271
    Location:33162
    LAG1-DNAbind; LAG1, DNA binding
  3. NM_001277116.1NP_001264045.1  recombining binding protein suppressor of hairless isoform 4

    See identical proteins and their annotated locations for NP_001264045.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (4) differs in the 5' UTR, contains an alternate exon in the 5' coding region, and initiates translation at an alternate start codon, compared to variant 1. The encoded isoform (4) is shorter and has a distinct N-terminus, compared to isoform 1.
    Source sequence(s)
    AK028363, AK132145, AK152746
    Consensus CDS
    CCDS80283.1
    UniProtKB/TrEMBL
    A0A0J9YTV5
    Related
    ENSMUSP00000143866.2, ENSMUST00000201912.4
    Conserved Domains (3) summary
    cd01176
    Location:357453
    IPT_RBP-Jkappa; IPT domain of the recombination signal Jkappa binding protein (RBP-Jkappa). RBP-J kappa, was initially considered to be involved in V(D)J recombination because of its DNA binding specificity and structural similarity to site-specific recombinases known ...
    pfam09270
    Location:186335
    BTD; Beta-trefoil DNA-binding domain
    pfam09271
    Location:55184
    LAG1-DNAbind; LAG1, DNA binding
  4. NM_001359152.1NP_001346081.1  recombining binding protein suppressor of hairless isoform 5

    Status: VALIDATED

    Description
    Transcript Variant: This variant (5) differs in the 5' UTR, lacks a portion of the 5' coding region, initiates translation at an alternate start codon, and lacks an alternate exon in the 3' end compared to variant 1, that causes a frameshift. The encoded isoform (5) has shorter and distinct N- and C-termini compared to isoform 1.
    Source sequence(s)
    AC084054
    Conserved Domains (2) summary
    pfam09270
    Location:166315
    BTD; Beta-trefoil DNA-binding domain
    pfam09271
    Location:35164
    LAG1-DNAbind; LAG1, DNA binding
  5. NM_009035.5NP_033061.3  recombining binding protein suppressor of hairless isoform 1

    See identical proteins and their annotated locations for NP_033061.3

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) encodes the longer isoform (1).
    Source sequence(s)
    AK028363, AK132145, AK152746, BY155397
    Consensus CDS
    CCDS19292.1
    UniProtKB/Swiss-Prot
    P31266, Q80UN8, Q8C4Z3
    Related
    ENSMUSP00000040694.7, ENSMUST00000037618.13
    Conserved Domains (3) summary
    cd01176
    Location:376472
    IPT_RBP-Jkappa; IPT domain of the recombination signal Jkappa binding protein (RBP-Jkappa). RBP-J kappa, was initially considered to be involved in V(D)J recombination because of its DNA binding specificity and structural similarity to site-specific recombinases known ...
    pfam09270
    Location:205354
    BTD; Beta-trefoil DNA-binding domain
    pfam09271
    Location:74203
    LAG1-DNAbind; LAG1, DNA binding

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000071.7 Reference GRCm39 C57BL/6J

    Range
    53713121..53814787
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006503799.4XP_006503862.1  recombining binding protein suppressor of hairless isoform X2

    See identical proteins and their annotated locations for XP_006503862.1

    UniProtKB/TrEMBL
    Q3U6F1
    Related
    ENSMUSP00000143846.2, ENSMUST00000201883.4
    Conserved Domains (3) summary
    cd01176
    Location:315411
    IPT_RBP-Jkappa; IPT domain of the recombination signal Jkappa binding protein (RBP-Jkappa). RBP-J kappa, was initially considered to be involved in V(D)J recombination because of its DNA binding specificity and structural similarity to site-specific recombinases known ...
    pfam09270
    Location:171293
    BTD; Beta-trefoil DNA-binding domain
    pfam09271
    Location:13138
    LAG1-DNAbind; LAG1, DNA binding
  2. XM_036164920.1XP_036020813.1  recombining binding protein suppressor of hairless isoform X2

    UniProtKB/TrEMBL
    Q3U6F1
    Conserved Domains (3) summary
    cd01176
    Location:315411
    IPT_RBP-Jkappa; IPT domain of the recombination signal Jkappa binding protein (RBP-Jkappa). RBP-J kappa, was initially considered to be involved in V(D)J recombination because of its DNA binding specificity and structural similarity to site-specific recombinases known ...
    pfam09270
    Location:171293
    BTD; Beta-trefoil DNA-binding domain
    pfam09271
    Location:13138
    LAG1-DNAbind; LAG1, DNA binding
  3. XM_036164921.1XP_036020814.1  recombining binding protein suppressor of hairless isoform X2

    UniProtKB/TrEMBL
    Q3U6F1
    Conserved Domains (3) summary
    cd01176
    Location:315411
    IPT_RBP-Jkappa; IPT domain of the recombination signal Jkappa binding protein (RBP-Jkappa). RBP-J kappa, was initially considered to be involved in V(D)J recombination because of its DNA binding specificity and structural similarity to site-specific recombinases known ...
    pfam09270
    Location:171293
    BTD; Beta-trefoil DNA-binding domain
    pfam09271
    Location:13138
    LAG1-DNAbind; LAG1, DNA binding
  4. XM_006503796.5XP_006503859.1  recombining binding protein suppressor of hairless isoform X1

    Conserved Domains (3) summary
    cd01176
    Location:379475
    IPT_RBP-Jkappa; IPT domain of the recombination signal Jkappa binding protein (RBP-Jkappa). RBP-J kappa, was initially considered to be involved in V(D)J recombination because of its DNA binding specificity and structural similarity to site-specific recombinases known ...
    pfam09270
    Location:208357
    BTD; Beta-trefoil DNA-binding domain
    pfam09271
    Location:77202
    LAG1-DNAbind; LAG1, DNA binding