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Rbmxl1 RNA binding motif protein, X-linked like-1 [ Mus musculus (house mouse) ]

Gene ID: 19656, updated on 12-Aug-2018

Summary

Official Symbol
Rbmxl1provided by MGI
Official Full Name
RNA binding motif protein, X-linked like-1provided by MGI
Primary source
MGI:MGI:1343045
See related
Ensembl:ENSMUSG00000037070 Vega:OTTMUSG00000061282
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Rbmx; Hnrpg; Rbmxrt
Expression
Broad expression in CNS E11.5 (RPKM 47.6), CNS E14 (RPKM 36.5) and 25 other tissues See more

Genomic context

See Rbmxl1 in Genome Data Viewer
Location:
8; 8 C1
Exon count:
3
Annotation release Status Assembly Chr Location
106 current GRCm38.p4 (GCF_000001635.24) 8 NC_000074.6 (78505269..78508928, complement)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 8 NC_000074.5 (81029168..81032827, complement)

Chromosome 8 - NC_000074.6Genomic Context describing neighboring genes Neighboring gene POU domain, class 4, transcription factor 2 Neighboring gene predicted gene 2225 Neighboring gene solute carrier family 10 (sodium/bile acid cotransporter family), member 7 Neighboring gene ribosomal protein L28 pseudogene Neighboring gene predicted gene, 39203

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Pathways from BioSystems

  • Spliceosome, organism-specific biosystem (from KEGG)
    Spliceosome, organism-specific biosystemAfter transcription, eukaryotic mRNA precursors contain protein-coding exons and noncoding introns. In the following splicing, introns are excised and exons are joined by a macromolecular complex, th...
  • Spliceosome, conserved biosystem (from KEGG)
    Spliceosome, conserved biosystemAfter transcription, eukaryotic mRNA precursors contain protein-coding exons and noncoding introns. In the following splicing, introns are excised and exons are joined by a macromolecular complex, th...
  • mRNA processing, organism-specific biosystem (from WikiPathways)
    mRNA processing, organism-specific biosystemAdapted from Reactome, see: [http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_1675.1 REACT 1675.1] This process describes the conversion of precursor messenger RNA into mature messenge...

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Clone Names

  • MGC102184

Gene Ontology Provided by MGI

Function Evidence Code Pubs
RNA binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
RNA binding ISO
Inferred from Sequence Orthology
more info
 
RNA polymerase II proximal promoter sequence-specific DNA binding IDA
Inferred from Direct Assay
more info
PubMed 
chromatin binding IDA
Inferred from Direct Assay
more info
PubMed 
nucleic acid binding IEA
Inferred from Electronic Annotation
more info
 
protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Process Evidence Code Pubs
RNA splicing IEA
Inferred from Electronic Annotation
more info
 
mRNA processing IEA
Inferred from Electronic Annotation
more info
 
mRNA splice site selection ISO
Inferred from Sequence Orthology
more info
 
negative regulation of mRNA splicing, via spliceosome ISO
Inferred from Sequence Orthology
more info
 
positive regulation of mRNA splicing, via spliceosome IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
positive regulation of mRNA splicing, via spliceosome ISO
Inferred from Sequence Orthology
more info
 
positive regulation of transcription by RNA polymerase II IDA
Inferred from Direct Assay
more info
PubMed 
positive regulation of transcription by RNA polymerase II IMP
Inferred from Mutant Phenotype
more info
PubMed 
protein homooligomerization ISO
Inferred from Sequence Orthology
more info
 
regulation of alternative mRNA splicing, via spliceosome ISO
Inferred from Sequence Orthology
more info
 
Component Evidence Code Pubs
nucleus IDA
Inferred from Direct Assay
more info
PubMed 
ribonucleoprotein complex IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
spliceosomal complex IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
supraspliceosomal complex ISO
Inferred from Sequence Orthology
more info
 

General protein information

Preferred Names
RNA binding motif protein, X-linked-like-1
Names
RNA binding motif protein, X chromosome retrogene
RNA-binding motif protein, X chromosome
heterogeneous nuclear ribonucleoprotein G (hnRNP G)
heterogeneous nuclear ribonucleoprotein G-like 1
hnRNP G

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001252089.1NP_001239018.1  RNA binding motif protein, X-linked-like-1

    See identical proteins and their annotated locations for NP_001239018.1

    Status: VALIDATED

    Source sequence(s)
    AK041927, BC089350, BY262810
    Consensus CDS
    CCDS22430.1
    UniProtKB/Swiss-Prot
    Q91VM5
    Related
    ENSMUSP00000147384.1, OTTMUSP00000077594, ENSMUST00000211719.1, OTTMUST00000149565
    Conserved Domains (2) summary
    cd12382
    Location:786
    RRM_RBMX_like; RNA recognition motif in heterogeneous nuclear ribonucleoprotein G (hnRNP G), Y chromosome RNA recognition motif 1 (hRBMY), testis-specific heterogeneous nuclear ribonucleoprotein G-T (hnRNP G-T) and similar proteins
    cl25887
    Location:10202
    RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]
  2. NM_001358974.1NP_001345903.1  RNA binding motif protein, X-linked-like-1

    Status: VALIDATED

    Source sequence(s)
    AC101757
    Conserved Domains (2) summary
    cd12382
    Location:786
    RRM_RBMX_like; RNA recognition motif in heterogeneous nuclear ribonucleoprotein G (hnRNP G), Y chromosome RNA recognition motif 1 (hRBMY), testis-specific heterogeneous nuclear ribonucleoprotein G-T (hnRNP G-T) and similar proteins
    cl25887
    Location:10202
    RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]
  3. NM_001358975.1NP_001345904.1  RNA binding motif protein, X-linked-like-1

    Status: VALIDATED

    Source sequence(s)
    AC101757
    Conserved Domains (2) summary
    cd12382
    Location:786
    RRM_RBMX_like; RNA recognition motif in heterogeneous nuclear ribonucleoprotein G (hnRNP G), Y chromosome RNA recognition motif 1 (hRBMY), testis-specific heterogeneous nuclear ribonucleoprotein G-T (hnRNP G-T) and similar proteins
    cl25887
    Location:10202
    RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]
  4. NM_009033.2NP_033059.2  RNA binding motif protein, X-linked-like-1

    See identical proteins and their annotated locations for NP_033059.2

    Status: VALIDATED

    Source sequence(s)
    BC089350, BY262810
    Consensus CDS
    CCDS22430.1
    UniProtKB/Swiss-Prot
    Q91VM5
    Related
    ENSMUSP00000048153.7, OTTMUSP00000077593, ENSMUST00000049245.9, OTTMUST00000149564
    Conserved Domains (2) summary
    cd12382
    Location:786
    RRM_RBMX_like; RNA recognition motif in heterogeneous nuclear ribonucleoprotein G (hnRNP G), Y chromosome RNA recognition motif 1 (hRBMY), testis-specific heterogeneous nuclear ribonucleoprotein G-T (hnRNP G-T) and similar proteins
    cl25887
    Location:10202
    RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm38.p4 C57BL/6J

Genomic

  1. NC_000074.6 Reference GRCm38.p4 C57BL/6J

    Range
    78505269..78508928 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006530776.2XP_006530839.1  RNA binding motif protein, X-linked-like-1 isoform X1

    UniProtKB/Swiss-Prot
    Q91VM5
    Conserved Domains (2) summary
    cd12382
    Location:786
    RRM_RBMX_like; RNA recognition motif in heterogeneous nuclear ribonucleoprotein G (hnRNP G), Y chromosome RNA recognition motif 1 (hRBMY), testis-specific heterogeneous nuclear ribonucleoprotein G-T (hnRNP G-T) and similar proteins
    cl25887
    Location:10202
    RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]
  2. XM_006530775.2XP_006530838.1  RNA binding motif protein, X-linked-like-1 isoform X1

    UniProtKB/Swiss-Prot
    Q91VM5
    Conserved Domains (2) summary
    cd12382
    Location:786
    RRM_RBMX_like; RNA recognition motif in heterogeneous nuclear ribonucleoprotein G (hnRNP G), Y chromosome RNA recognition motif 1 (hRBMY), testis-specific heterogeneous nuclear ribonucleoprotein G-T (hnRNP G-T) and similar proteins
    cl25887
    Location:10202
    RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]
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