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OR56B4 olfactory receptor family 56 subfamily B member 4 [ Homo sapiens (human) ]

Gene ID: 196335, updated on 2-Nov-2024

Summary

Official Symbol
OR56B4provided by HGNC
Official Full Name
olfactory receptor family 56 subfamily B member 4provided by HGNC
Primary source
HGNC:HGNC:15248
See related
Ensembl:ENSG00000180919 AllianceGenome:HGNC:15248
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
OR11-67
Summary
Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. [provided by RefSeq, Jul 2008]
Orthologs
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Genomic context

See OR56B4 in Genome Data Viewer
Location:
11p15.4
Exon count:
1
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 11 NC_000011.10 (6107684..6108835)
RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 11 NC_060935.1 (6166118..6167269)
RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 11 NC_000011.9 (6128914..6130065)

Chromosome 11 - NC_000011.10Genomic Context describing neighboring genes Neighboring gene olfactory receptor family 52 subfamily L member 2 pseudogene Neighboring gene OCT4-NANOG-H3K27ac hESC enhancer GRCh37_chr11:6091219-6091790 Neighboring gene olfactory receptor family 52 subfamily X member 1 pseudogene Neighboring gene OCT4-NANOG hESC enhancer GRCh37_chr11:6097755-6098296 Neighboring gene uncharacterized LOC124902622 Neighboring gene olfactory receptor family 56 subfamily B member 3 pseudogene Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr11:6164539-6165130 Neighboring gene olfactory receptor family 52 subfamily B member 1 pseudogene

Genomic regions, transcripts, and products

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables G protein-coupled receptor activity IEA
Inferred from Electronic Annotation
more info
 
enables olfactory receptor activity IBA
Inferred from Biological aspect of Ancestor
more info
 
Component Evidence Code Pubs
is_active_in plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
 

General protein information

Preferred Names
olfactory receptor 56B4
Names
olfactory receptor OR11-67

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001005181.2NP_001005181.1  olfactory receptor 56B4

    Status: PROVISIONAL

    Source sequence(s)
    BC136880
    Consensus CDS
    CCDS31406.1
    UniProtKB/Swiss-Prot
    Q6IFD7, Q8NH76
    UniProtKB/TrEMBL
    A0A126GVL4
    Related
    ENSP00000321196.2, ENST00000316529.3
    Conserved Domains (2) summary
    cd14964
    Location:6688
    7tm_GPCRs; TM helix 2 [structural motif]
    cl28897
    Location:51307
    7tm_GPCRs; seven-transmembrane G protein-coupled receptor superfamily

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000011.10 Reference GRCh38.p14 Primary Assembly

    Range
    6107684..6108835
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060935.1 Alternate T2T-CHM13v2.0

    Range
    6166118..6167269
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)