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ANTXRL ANTXR like [ Homo sapiens (human) ]

Gene ID: 195977, updated on 8-Dec-2022

Summary

Official Symbol
ANTXRLprovided by HGNC
Official Full Name
ANTXR likeprovided by HGNC
Primary source
HGNC:HGNC:27277
See related
Ensembl:ENSG00000274209 AllianceGenome:HGNC:27277
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Summary
Predicted to enable transmembrane signaling receptor activity. Predicted to be involved in toxin transport. Predicted to be integral component of membrane. Predicted to be active in cell surface and plasma membrane. [provided by Alliance of Genome Resources, Apr 2022]
Expression
Restricted expression toward testis (RPKM 3.2) See more
Orthologs
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Genomic context

See ANTXRL in Genome Data Viewer
Location:
10q11.22
Exon count:
27
Annotation release Status Assembly Chr Location
110 current GRCh38.p14 (GCF_000001405.40) 10 NC_000010.11 (46286092..46330129)
110 current T2T-CHM13v2.0 (GCF_009914755.1) 10 NC_060934.1 (47173135..47216165)
105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 10 NC_000010.10 (47658233..47701365)

Chromosome 10 - NC_000010.11Genomic Context describing neighboring genes Neighboring gene ANTXR like pseudogene 1 Neighboring gene adenosylhomocysteinase pseudogene 1 Neighboring gene uncharacterized LOC105378577 Neighboring gene ArfGAP with GTPase domain, ankyrin repeat and PH domain 14, pseudogene Neighboring gene protein FAM25

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

General gene information

Markers

Homology

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
 
enables transmembrane signaling receptor activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Process Evidence Code Pubs
involved_in toxin transport IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 

General protein information

Preferred Names
anthrax toxin receptor-like
Names
anthrax toxin receptor like

NCBI Reference Sequences (RefSeq)

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001278688.3NP_001265617.1  anthrax toxin receptor-like isoform 1 precursor

    See identical proteins and their annotated locations for NP_001265617.1

    Status: VALIDATED

    Source sequence(s)
    AC244230, AL450388
    Consensus CDS
    CCDS60524.1
    UniProtKB/Swiss-Prot
    A6NF34, H3BPS2
    UniProtKB/TrEMBL
    A0A2U7XUX1
    Related
    ENSP00000480615.1, ENST00000620264.5
    Conserved Domains (3) summary
    pfam05587
    Location:249348
    Anth_Ig; Anthrax receptor extracellular domain
    pfam15800
    Location:490612
    CiPC; Clock interacting protein circadian
    cl00057
    Location:71254
    vWFA; Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b para-rossmann type of ...
  2. NM_001354208.2NP_001341137.1  anthrax toxin receptor-like isoform 2

    Status: VALIDATED

    Source sequence(s)
    AC244230, AL450388

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 110 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000010.11 Reference GRCh38.p14 Primary Assembly

    Range
    46286092..46330129
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_047424705.1XP_047280661.1  anthrax toxin receptor-like isoform X5

  2. XM_011539430.3XP_011537732.1  anthrax toxin receptor-like isoform X1

    Conserved Domains (2) summary
    pfam05587
    Location:256348
    Anth_Ig; Anthrax receptor extracellular domain
    cl00057
    Location:71254
    vWFA; Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b para-rossmann type of ...
  3. XM_006717684.4XP_006717747.1  anthrax toxin receptor-like isoform X2

    Conserved Domains (2) summary
    pfam05587
    Location:256349
    Anth_Ig; Anthrax receptor extracellular domain
    cl00057
    Location:71254
    vWFA; Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b para-rossmann type of ...
  4. XM_011539442.1XP_011537744.1  anthrax toxin receptor-like isoform X9

    Conserved Domains (2) summary
    pfam05587
    Location:256350
    Anth_Ig; Anthrax receptor extracellular domain
    cl00057
    Location:71254
    vWFA; Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b para-rossmann type of ...
  5. XM_011539441.1XP_011537743.1  anthrax toxin receptor-like isoform X8

    Conserved Domains (2) summary
    pfam05587
    Location:256349
    Anth_Ig; Anthrax receptor extracellular domain
    cl00057
    Location:71254
    vWFA; Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b para-rossmann type of ...
  6. XM_047424706.1XP_047280662.1  anthrax toxin receptor-like isoform X5

  7. XM_047424704.1XP_047280660.1  anthrax toxin receptor-like isoform X5

  8. XM_011539437.3XP_011537739.1  anthrax toxin receptor-like isoform X7

    See identical proteins and their annotated locations for XP_011537739.1

    Conserved Domains (2) summary
    pfam05587
    Location:105197
    Anth_Ig; Anthrax receptor extracellular domain
    cl00057
    Location:1103
    vWFA; Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b para-rossmann type of ...
  9. XM_047424707.1XP_047280663.1  anthrax toxin receptor-like isoform X6

  10. XM_011539433.3XP_011537735.1  anthrax toxin receptor-like isoform X6

    See identical proteins and their annotated locations for XP_011537735.1

    Conserved Domains (2) summary
    pfam05587
    Location:145237
    Anth_Ig; Anthrax receptor extracellular domain
    cl00057
    Location:1143
    vWFA; Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b para-rossmann type of ...
  11. XM_011539438.3XP_011537740.1  anthrax toxin receptor-like isoform X7

    See identical proteins and their annotated locations for XP_011537740.1

    Conserved Domains (2) summary
    pfam05587
    Location:105197
    Anth_Ig; Anthrax receptor extracellular domain
    cl00057
    Location:1103
    vWFA; Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b para-rossmann type of ...
  12. XM_017015818.2XP_016871307.1  anthrax toxin receptor-like isoform X4

  13. XM_011539434.3XP_011537736.1  anthrax toxin receptor-like isoform X6

    See identical proteins and their annotated locations for XP_011537736.1

    Conserved Domains (2) summary
    pfam05587
    Location:145237
    Anth_Ig; Anthrax receptor extracellular domain
    cl00057
    Location:1143
    vWFA; Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b para-rossmann type of ...
  14. XM_047424708.1XP_047280664.1  anthrax toxin receptor-like isoform X7

  15. XM_017015819.2XP_016871308.1  anthrax toxin receptor-like isoform X7

    Conserved Domains (2) summary
    pfam05587
    Location:105197
    Anth_Ig; Anthrax receptor extracellular domain
    cl00057
    Location:1103
    vWFA; Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b para-rossmann type of ...
  16. XM_011539431.3XP_011537733.1  anthrax toxin receptor-like isoform X3

    Conserved Domains (2) summary
    pfam05587
    Location:187279
    Anth_Ig; Anthrax receptor extracellular domain
    cl00057
    Location:37185
    vWFA; Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b para-rossmann type of ...
  17. XM_011539443.2XP_011537745.1  anthrax toxin receptor-like isoform X10

RNA

  1. XR_945612.2 RNA Sequence

  2. XR_945614.2 RNA Sequence

  3. XR_945615.1 RNA Sequence

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060934.1 Alternate T2T-CHM13v2.0

    Range
    47173135..47216165
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

  1. NR_003601.1: Suppressed sequence

    Description
    NR_003601.1: This RefSeq was permanently suppressed because currently there is insufficient support for the transcript.