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Tmprss11a transmembrane protease, serine 11a [ Mus musculus (house mouse) ]

Gene ID: 194597, updated on 27-Jan-2018
Official Symbol
Tmprss11aprovided by MGI
Official Full Name
transmembrane protease, serine 11aprovided by MGI
Primary source
MGI:MGI:2684853
See related
Ensembl:ENSMUSG00000072845 Vega:OTTMUSG00000035104
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Gm7
Expression
Low expression observed in reference dataset See more
See Tmprss11a in Genome Data Viewer
Location:
5; 5 E1
Exon count:
10
Annotation release Status Assembly Chr Location
106 current GRCm38.p4 (GCF_000001635.24) 5 NC_000071.6 (86410410..86469175, complement)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 5 NC_000071.5 (86839435..86898015, complement)

Chromosome 5 - NC_000071.6Genomic Context describing neighboring genes Neighboring gene transmembrane protease, serine 11c Neighboring gene transmembrane protease, serine 11d Neighboring gene predicted gene, 35367 Neighboring gene transmembrane protease, serine 11g Neighboring gene transmembrane protease, serine 11f

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Targeted (1) 

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
hydrolase activity IEA
Inferred from Electronic Annotation
more info
 
peptidase activity IEA
Inferred from Electronic Annotation
more info
 
serine-type endopeptidase activity IEA
Inferred from Electronic Annotation
more info
 
serine-type peptidase activity IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
cell cycle IEA
Inferred from Electronic Annotation
more info
 
proteolysis IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
extracellular region IEA
Inferred from Electronic Annotation
more info
 
integral component of membrane IEA
Inferred from Electronic Annotation
more info
 
integral component of plasma membrane IEA
Inferred from Electronic Annotation
more info
 
membrane IEA
Inferred from Electronic Annotation
more info
 
Preferred Names
transmembrane protease serine 11A
Names
DESC-3
airway trypsin-like protease 1
serine protease DESC3

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001033233.2NP_001028405.1  transmembrane protease serine 11A

    See identical proteins and their annotated locations for NP_001028405.1

    Status: PROVISIONAL

    Source sequence(s)
    AK142820
    Consensus CDS
    CCDS51531.1
    UniProtKB/Swiss-Prot
    Q3UQ41
    Related
    ENSMUSP00000098634.2, OTTMUSP00000048793, ENSMUST00000101073.2, OTTMUST00000089304
    Conserved Domains (3) summary
    smart00020
    Location:157383
    Tryp_SPc; Trypsin-like serine protease
    cd00190
    Location:158386
    Tryp_SPc; Trypsin-like serine protease; Many of these are synthesized as inactive precursor zymogens that are cleaved during limited proteolysis to generate their active forms. Alignment contains also inactive enzymes that have substitutions of the catalytic triad ...
    pfam01390
    Location:39128
    SEA; SEA domain

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm38.p4 C57BL/6J

Genomic

  1. NC_000071.6 Reference GRCm38.p4 C57BL/6J

    Range
    86410410..86469175 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006534840.2XP_006534903.1  transmembrane protease serine 11A isoform X1

    Conserved Domains (3) summary
    smart00020
    Location:160386
    Tryp_SPc; Trypsin-like serine protease
    cd00190
    Location:161389
    Tryp_SPc; Trypsin-like serine protease; Many of these are synthesized as inactive precursor zymogens that are cleaved during limited proteolysis to generate their active forms. Alignment contains also inactive enzymes that have substitutions of the catalytic triad ...
    pfam01390
    Location:42131
    SEA; SEA domain
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