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Trpv5 transient receptor potential cation channel, subfamily V, member 5 [ Mus musculus (house mouse) ]

Gene ID: 194352, updated on 8-Dec-2018

Summary

Official Symbol
Trpv5provided by MGI
Official Full Name
transient receptor potential cation channel, subfamily V, member 5provided by MGI
Primary source
MGI:MGI:2429764
See related
Ensembl:ENSMUSG00000036899
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
CAT2; ECAC1; D630033B11
Expression
Biased expression in kidney adult (RPKM 1.9), placenta adult (RPKM 0.2) and 2 other tissues See more
Orthologs

Genomic context

See Trpv5 in Genome Data Viewer
Location:
6; 6 B2.1
Exon count:
16
Annotation release Status Assembly Chr Location
106 current GRCm38.p4 (GCF_000001635.24) 6 NC_000072.6 (41651661..41681453, complement)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 6 NC_000072.5 (41602769..41630722, complement)

Chromosome 6 - NC_000072.6Genomic Context describing neighboring genes Neighboring gene Eph receptor B6 Neighboring gene predicted gene, 38795 Neighboring gene transient receptor potential cation channel, subfamily V, member 6 Neighboring gene predicted gene, 34642 Neighboring gene LLLL and CFNLAS motif containing 1 Neighboring gene Kell blood group

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)

Pathways from BioSystems

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • MGC129346, MGC129347

Gene Ontology Provided by MGI

Function Evidence Code Pubs
calcium channel activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
calcium channel activity IDA
Inferred from Direct Assay
more info
PubMed 
calcium channel activity ISO
Inferred from Sequence Orthology
more info
 
calmodulin binding IEA
Inferred from Electronic Annotation
more info
 
ion channel activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
metal ion binding IEA
Inferred from Electronic Annotation
more info
 
protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Process Evidence Code Pubs
calcium ion homeostasis IMP
Inferred from Mutant Phenotype
more info
PubMed 
calcium ion import across plasma membrane ISO
Inferred from Sequence Orthology
more info
 
calcium ion transmembrane transport ISO
Inferred from Sequence Orthology
more info
 
calcium ion transport IDA
Inferred from Direct Assay
more info
PubMed 
calcium ion transport into cytosol ISO
Inferred from Sequence Orthology
more info
 
cellular calcium ion homeostasis NAS
Non-traceable Author Statement
more info
PubMed 
ion transport IEA
Inferred from Electronic Annotation
more info
 
protein tetramerization IDA
Inferred from Direct Assay
more info
PubMed 
regulation of urine volume IMP
Inferred from Mutant Phenotype
more info
PubMed 
transmembrane transport IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
apical plasma membrane IDA
Inferred from Direct Assay
more info
PubMed 
apical plasma membrane ISO
Inferred from Sequence Orthology
more info
 
cell ISO
Inferred from Sequence Orthology
more info
 
integral component of membrane IEA
Inferred from Electronic Annotation
more info
 
integral component of plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
integral component of plasma membrane ISO
Inferred from Sequence Orthology
more info
 
intrinsic component of plasma membrane ISO
Inferred from Sequence Orthology
more info
 
membrane IEA
Inferred from Electronic Annotation
more info
 
plasma membrane IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
transient receptor potential cation channel subfamily V member 5
Names
OTRPC3
calcium transport protein 2
epithelial calcium channel 1
osm-9-like TRP channel 3

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001007572.2NP_001007573.1  transient receptor potential cation channel subfamily V member 5

    See identical proteins and their annotated locations for NP_001007573.1

    Status: PROVISIONAL

    Source sequence(s)
    BC110555
    Consensus CDS
    CCDS20053.1
    UniProtKB/Swiss-Prot
    P69744
    Related
    ENSMUSP00000031901.5, ENSMUST00000031901.10
    Conserved Domains (3) summary
    cd00204
    Location:73214
    ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
    TIGR00870
    Location:5701
    trp; transient-receptor-potential calcium channel protein
    sd00045
    Location:111154
    ANK; ANK repeat [structural motif]

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm38.p4 C57BL/6J

Genomic

  1. NC_000072.6 Reference GRCm38.p4 C57BL/6J

    Range
    41651661..41681453 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_017321464.1XP_017176953.1  transient receptor potential cation channel subfamily V member 5 isoform X2

  2. XM_017321463.1XP_017176952.1  transient receptor potential cation channel subfamily V member 5 isoform X1

    UniProtKB/Swiss-Prot
    P69744
    Conserved Domains (3) summary
    cd00204
    Location:73214
    ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
    TIGR00870
    Location:5701
    trp; transient-receptor-potential calcium channel protein
    sd00045
    Location:111154
    ANK; ANK repeat [structural motif]
  3. XM_006505770.3XP_006505833.1  transient receptor potential cation channel subfamily V member 5 isoform X3

    Conserved Domains (4) summary
    cd00204
    Location:22163
    ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
    pfam00520
    Location:349532
    Ion_trans; Ion transport protein
    pfam12796
    Location:26136
    Ank_2; Ankyrin repeats (3 copies)
    sd00045
    Location:60103
    ANK; ANK repeat [structural motif]
  4. XM_006505771.2XP_006505834.1  transient receptor potential cation channel subfamily V member 5 isoform X4

    Conserved Domains (5) summary
    cd00204
    Location:36182
    ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
    pfam00520
    Location:281464
    Ion_trans; Ion transport protein
    pfam12796
    Location:168
    Ank_2; Ankyrin repeats (3 copies)
    pfam13637
    Location:4095
    Ank_4; Ankyrin repeats (many copies)
    sd00045
    Location:3768
    ANK; ANK repeat [structural motif]
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