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Airim AFG2 interacting ribosome maturation factor [ Mus musculus (house mouse) ]

Gene ID: 194268, updated on 5-Mar-2024

Summary

Official Symbol
Airimprovided by MGI
Official Full Name
AFG2 interacting ribosome maturation factorprovided by MGI
Primary source
MGI:MGI:3041172
See related
Ensembl:ENSMUSG00000044730 AllianceGenome:MGI:3041172
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
C1orf109; 9930104L06Rik
Summary
Predicted to be located in cytosol; nucleolus; and nucleoplasm. Predicted to be active in cytoplasm and nucleus. Orthologous to human C1orf109 (chromosome 1 open reading frame 109). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in CNS E11.5 (RPKM 5.8), limb E14.5 (RPKM 5.5) and 28 other tissues See more
Orthologs
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Genomic context

See Airim in Genome Data Viewer
Location:
4 D2.2; 4 57.94 cM
Exon count:
5
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 4 NC_000070.7 (124830777..124838454)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 4 NC_000070.6 (124936984..124944661)

Chromosome 4 - NC_000070.7Genomic Context describing neighboring genes Neighboring gene RIKEN cDNA 1700125G02 gene Neighboring gene Eph receptor A10 Neighboring gene cell division cycle associated 8 Neighboring gene STARR-positive B cell enhancer ABC_E424 Neighboring gene STARR-positive B cell enhancer ABC_E4665 Neighboring gene predicted gene 12930 Neighboring gene predicted gene, 32371 Neighboring gene R-spondin 1

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

General gene information

Markers

Clone Names

  • MGC107426

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
 
Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
 
involved_in ribosomal large subunit biogenesis ISO
Inferred from Sequence Orthology
more info
 
acts_upstream_of_or_within ribosome biogenesis IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in cytoplasm ISO
Inferred from Sequence Orthology
more info
 
located_in cytosol ISO
Inferred from Sequence Orthology
more info
 
located_in nucleolus ISO
Inferred from Sequence Orthology
more info
 
located_in nucleoplasm ISO
Inferred from Sequence Orthology
more info
 
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in nucleus ISO
Inferred from Sequence Orthology
more info
 

General protein information

Preferred Names
AFG2-interacting ribosome maturation factor
Names
ribosome biogenesis protein C1orf109 homolog
uncharacterized protein C1orf109 homolog

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001355603.1NP_001342532.1  AFG2-interacting ribosome maturation factor

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) differs in the 5' UTR compared to variant 1. Variants 1-3 encode the same protein.
    Source sequence(s)
    AK037053, AK158126, AL606933, BY781867
    Consensus CDS
    CCDS89826.1
    UniProtKB/Swiss-Prot
    Q148T1, Q3TU44, Q499E6, Q8BI05
    Conserved Domains (1) summary
    pfam15011
    Location:13167
    CK2S; Casein Kinase 2 substrate
  2. NM_001355605.1NP_001342534.1  AFG2-interacting ribosome maturation factor

    Status: VALIDATED

    Description
    Transcript Variant: This variant (3) differs in the 5' UTR compared to variant 1. Variants 1-3 encode the same protein.
    Source sequence(s)
    AK037053, AK158126, AL606933, BY781867
    Consensus CDS
    CCDS89826.1
    UniProtKB/Swiss-Prot
    Q148T1, Q3TU44, Q499E6, Q8BI05
    Conserved Domains (1) summary
    pfam15011
    Location:13167
    CK2S; Casein Kinase 2 substrate
  3. NM_177573.3NP_808241.2  AFG2-interacting ribosome maturation factor

    See identical proteins and their annotated locations for NP_808241.2

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the longest transcript. Variants 1-3 encode the same protein.
    Source sequence(s)
    AK158126, AL606933
    Consensus CDS
    CCDS89826.1
    UniProtKB/Swiss-Prot
    Q148T1, Q3TU44, Q499E6, Q8BI05
    Related
    ENSMUSP00000154851.2, ENSMUST00000094769.13
    Conserved Domains (1) summary
    pfam15011
    Location:13167
    CK2S; Casein Kinase 2 substrate

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000070.7 Reference GRCm39 C57BL/6J

    Range
    124830777..124838454
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006502884.4XP_006502947.1  AFG2-interacting ribosome maturation factor isoform X1

    See identical proteins and their annotated locations for XP_006502947.1

    Conserved Domains (1) summary
    pfam15011
    Location:13167
    CK2S; Casein Kinase 2 substrate
  2. XM_006502885.3XP_006502948.1  AFG2-interacting ribosome maturation factor isoform X1

    See identical proteins and their annotated locations for XP_006502948.1

    Conserved Domains (1) summary
    pfam15011
    Location:13167
    CK2S; Casein Kinase 2 substrate