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Abhd16a abhydrolase domain containing 16A [ Mus musculus (house mouse) ]

Gene ID: 193742, updated on 10-Mar-2023

Summary

Official Symbol
Abhd16aprovided by MGI
Official Full Name
abhydrolase domain containing 16Aprovided by MGI
Primary source
MGI:MGI:99476
See related
Ensembl:ENSMUSG00000007036 AllianceGenome:MGI:99476
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Bat5; NG26; Bat-5; mBAT5; D17H6S82E
Summary
Enables acylglycerol lipase activity and phospholipase activity. Involved in monoacylglycerol catabolic process; phosphatidylserine catabolic process; and prostaglandin catabolic process. Predicted to be integral component of membrane. Predicted to be active in membrane. Orthologous to human ABHD16A (abhydrolase domain containing 16A, phospholipase). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in cerebellum adult (RPKM 54.1), adrenal adult (RPKM 49.8) and 28 other tissues See more
Orthologs
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Genomic context

See Abhd16a in Genome Data Viewer
Location:
17 B1; 17 18.59 cM
Exon count:
21
Annotation release Status Assembly Chr Location
109 current GRCm39 (GCF_000001635.27) 17 NC_000083.7 (35308210..35321963)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 17 NC_000083.6 (35089234..35102987)

Chromosome 17 - NC_000083.7Genomic Context describing neighboring genes Neighboring gene lymphocyte antigen 6 complex, locus G6D Neighboring gene lymphocyte antigen 6 complex, locus G6E Neighboring gene lymphocyte antigen 6 complex, locus G6F Neighboring gene lymphocyte antigen 6 complex, locus G5C Neighboring gene lymphocyte antigen 6 complex, locus G5B Neighboring gene casein kinase 2, beta polypeptide

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Targeted (1) 
  • Endonuclease-mediated (1) 

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • MGC19234

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables acylglycerol lipase activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables acylglycerol lipase activity IDA
Inferred from Direct Assay
more info
PubMed 
enables acylglycerol lipase activity ISO
Inferred from Sequence Orthology
more info
 
enables hydrolase activity IEA
Inferred from Electronic Annotation
more info
 
enables phospholipase activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables phospholipase activity IDA
Inferred from Direct Assay
more info
PubMed 
Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
phosphatidylserine lipase ABHD16A
Names
HLA-B associated transcript 5
abhydrolase domain-containing protein 16A
alpha/beta hydrolase domain-containing protein 16A
monoacylglycerol lipase ABHD16A
protein ABHD16A
protein BAT5
NP_848707.1
XP_030105460.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001410340.1NP_001397269.1  phosphatidylserine lipase ABHD16A isoform 2

    Status: VALIDATED

    Source sequence(s)
    AC087117
  2. NM_001410341.1NP_001397270.1  phosphatidylserine lipase ABHD16A isoform 3

    Status: VALIDATED

    Source sequence(s)
    AC087117
  3. NM_001410342.1NP_001397271.1  phosphatidylserine lipase ABHD16A isoform 4

    Status: VALIDATED

    Source sequence(s)
    AC087117
  4. NM_001410343.1NP_001397272.1  phosphatidylserine lipase ABHD16A isoform 5

    Status: VALIDATED

    Source sequence(s)
    AC087117
  5. NM_001410345.1NP_001397274.1  phosphatidylserine lipase ABHD16A isoform 6

    Status: VALIDATED

    Source sequence(s)
    AC087117
  6. NM_001410346.1NP_001397275.1  phosphatidylserine lipase ABHD16A isoform 7

    Status: VALIDATED

    Source sequence(s)
    AC087117
  7. NM_001410347.1NP_001397276.1  phosphatidylserine lipase ABHD16A isoform 8

    Status: VALIDATED

    Source sequence(s)
    AC087117
  8. NM_001417679.1NP_001404608.1  phosphatidylserine lipase ABHD16A isoform 9

    Status: VALIDATED

    Source sequence(s)
    AC087117
  9. NM_178592.4NP_848707.1  phosphatidylserine lipase ABHD16A isoform 1

    See identical proteins and their annotated locations for NP_848707.1

    Status: VALIDATED

    Source sequence(s)
    AC087117
    Consensus CDS
    CCDS28681.1
    UniProtKB/Swiss-Prot
    Q9Z1Q2
    Related
    ENSMUSP00000007251.8, ENSMUST00000007251.14
    Conserved Domains (1) summary
    pfam00561
    Location:280408
    Abhydrolase_1; alpha/beta hydrolase fold

RNA

  1. NR_177060.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AC087117
  2. NR_177061.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AC087117
  3. NR_184561.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AC087117

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000083.7 Reference GRCm39 C57BL/6J

    Range
    35308210..35321963
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_030249600.1XP_030105460.1  phosphatidylserine lipase ABHD16A isoform X1

    Conserved Domains (1) summary
    pfam00561
    Location:174302
    Abhydrolase_1; alpha/beta hydrolase fold

RNA

  1. XR_385303.5 RNA Sequence

  2. XR_004939480.1 RNA Sequence

  3. XR_001782059.3 RNA Sequence

    Related
    ENSMUST00000173846.8