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Zfp3 zinc finger protein 3 [ Mus musculus (house mouse) ]

Gene ID: 193043, updated on 8-Dec-2022

Summary

Official Symbol
Zfp3provided by MGI
Official Full Name
zinc finger protein 3provided by MGI
Primary source
MGI:MGI:99177
See related
Ensembl:ENSMUSG00000043602 AllianceGenome:MGI:99177
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Fnp-1; Zfp-3; B230309J24
Summary
Predicted to enable DNA-binding transcription repressor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. Predicted to be active in nucleoplasm. Is expressed in genitourinary system. Orthologous to human ZFP3 (ZFP3 zinc finger protein). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in CNS E18 (RPKM 3.0), cerebellum adult (RPKM 2.9) and 28 other tissues See more
Orthologs
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Genomic context

See Zfp3 in Genome Data Viewer
Location:
11 B3; 11 43.21 cM
Exon count:
2
Annotation release Status Assembly Chr Location
109 current GRCm39 (GCF_000001635.27) 11 NC_000077.7 (70655273..70663754)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 11 NC_000077.6 (70764447..70772928)

Chromosome 11 - NC_000077.7Genomic Context describing neighboring genes Neighboring gene predicted gene 12320 Neighboring gene 39S ribosomal protein L42, mitochondrial pseudogene Neighboring gene SLP adaptor and CSK interacting membrane protein Neighboring gene rabaptin, RAB GTPase binding effector protein 1 Neighboring gene ribosomal protein L23A, pseudogene 2

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (1) 

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables DNA binding IEA
Inferred from Electronic Annotation
more info
 
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
involved_in negative regulation of transcription by RNA polymerase II IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in regulation of cytokine production IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in regulation of immune system process IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Component Evidence Code Pubs
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_177565.3NP_808233.1  zinc finger protein 3

    See identical proteins and their annotated locations for NP_808233.1

    Status: VALIDATED

    Source sequence(s)
    AI854635, AK045753
    Consensus CDS
    CCDS24966.1
    UniProtKB/Swiss-Prot
    Q8BLB0
    Related
    ENSMUSP00000054020.6, ENSMUST00000060444.6
    Conserved Domains (4) summary
    COG5048
    Location:134494
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:166186
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam00096
    Location:136158
    zf-C2H2; Zinc finger, C2H2 type
    pfam13465
    Location:374399
    zf-H2C2_2; Zinc-finger double domain

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000077.7 Reference GRCm39 C57BL/6J

    Range
    70655273..70663754
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)