U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Nacad NAC alpha domain containing [ Mus musculus (house mouse) ]

Gene ID: 192950, updated on 12-May-2024

Summary

Official Symbol
Nacadprovided by MGI
Official Full Name
NAC alpha domain containingprovided by MGI
Primary source
MGI:MGI:3603030
See related
Ensembl:ENSMUSG00000041073 AllianceGenome:MGI:3603030
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
mKIAA0363; D230024G13Rik
Summary
Predicted to enable unfolded protein binding activity. Predicted to be involved in protein targeting to membrane. Predicted to act upstream of or within protein transport. Predicted to be located in nucleus. Predicted to be part of nascent polypeptide-associated complex. Predicted to be active in cytoplasm. Is expressed in gut; nervous system; and sensory organ. Orthologous to human NACAD (NAC alpha domain containing). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Broad expression in whole brain E14.5 (RPKM 24.4), CNS E14 (RPKM 20.3) and 15 other tissues See more
Orthologs
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

See Nacad in Genome Data Viewer
Location:
11 A1; 11 4.6 cM
Exon count:
8
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 11 NC_000077.7 (6547814..6556059, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 11 NC_000077.6 (6597814..6606059, complement)

Chromosome 11 - NC_000077.7Genomic Context describing neighboring genes Neighboring gene predicted gene, 24000 Neighboring gene cerebral cavernous malformation 2 Neighboring gene STARR-positive B cell enhancer mm9_chr11:6481502-6481803 Neighboring gene transforming growth factor beta regulated gene 4 Neighboring gene predicted gene, 24313 Neighboring gene small nucleolar RNA, H/ACA box 5C

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (2) 
  • Targeted (1) 

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Clone Names

  • KIAA0363

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables unfolded protein binding IBA
Inferred from Biological aspect of Ancestor
more info
 
Process Evidence Code Pubs
involved_in protein targeting to membrane IBA
Inferred from Biological aspect of Ancestor
more info
 
acts_upstream_of_or_within protein transport IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
 
part_of nascent polypeptide-associated complex IEA
Inferred from Electronic Annotation
more info
 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
NAC-alpha domain-containing protein 1
NP_001075121.1
XP_036012341.1

NCBI Reference Sequences (RefSeq)

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001081652.1NP_001075121.1  NAC-alpha domain-containing protein 1

    See identical proteins and their annotated locations for NP_001075121.1

    Status: VALIDATED

    Source sequence(s)
    BC072589
    Consensus CDS
    CCDS36108.1
    UniProtKB/Swiss-Prot
    Q5SWP3, Q6I6F5
    Related
    ENSMUSP00000049490.4, ENSMUST00000045713.4
    Conserved Domains (3) summary
    COG1308
    Location:13581504
    EGD2; Transcription factor homologous to NACalpha-BTF3 [Transcription]
    cd14416
    Location:14631504
    UBA_NACAD; UBA-like domain found in nascent polypeptide-associated complex subunit alpha domain-containing protein 1 (NACAD)
    pfam01849
    Location:13591412
    NAC; NAC domain

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000077.7 Reference GRCm39 C57BL/6J

    Range
    6547814..6556059 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_036156448.1XP_036012341.1  NAC-alpha domain-containing protein 1 isoform X1

RNA

  1. XR_380961.2 RNA Sequence

  2. XR_003949359.1 RNA Sequence