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Ptgfrn prostaglandin F2 receptor negative regulator [ Mus musculus (house mouse) ]

Gene ID: 19221, updated on 12-May-2024

Summary

Official Symbol
Ptgfrnprovided by MGI
Official Full Name
prostaglandin F2 receptor negative regulatorprovided by MGI
Primary source
MGI:MGI:1277114
See related
Ensembl:ENSMUSG00000027864 AllianceGenome:MGI:1277114
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
FPRP; EWI-F; CD9P-1; Trim45; 4833445A08Rik
Summary
Involved in myoblast fusion involved in skeletal muscle regeneration. Acts upstream of or within lipid droplet organization. Predicted to be located in Golgi apparatus; endoplasmic reticulum; and membrane. Predicted to be integral component of membrane. Is expressed in several structures, including alimentary system; central nervous system; glans of male genital tubercle; skeleton; and vibrissa. Orthologous to human PTGFRN (prostaglandin F2 receptor inhibitor). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Broad expression in lung adult (RPKM 30.6), bladder adult (RPKM 17.8) and 21 other tissues See more
Orthologs
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Genomic context

See Ptgfrn in Genome Data Viewer
Location:
3 F2.2; 3 43.93 cM
Exon count:
11
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 3 NC_000069.7 (100947546..101018061, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 3 NC_000069.6 (101040230..101110745, complement)

Chromosome 3 - NC_000069.7Genomic Context describing neighboring genes Neighboring gene STARR-positive B cell enhancer ABC_E2678 Neighboring gene transcription termination factor, RNA polymerase II Neighboring gene CD101 antigen Neighboring gene STARR-seq mESC enhancer starr_08505 Neighboring gene STARR-seq mESC enhancer starr_08514 Neighboring gene STARR-seq mESC enhancer starr_08516 Neighboring gene STARR-seq mESC enhancer starr_08517 Neighboring gene STARR-seq mESC enhancer starr_08518 Neighboring gene nuclear import 7 pseudogene Neighboring gene tumor protein, translationally-controlled, pseudogene 1

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (3) 
  • Gene trapped (1) 

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Component Evidence Code Pubs
located_in Golgi apparatus IEA
Inferred from Electronic Annotation
more info
 
located_in endoplasmic reticulum IEA
Inferred from Electronic Annotation
more info
 
is_active_in membrane IBA
Inferred from Biological aspect of Ancestor
more info
 

General protein information

Preferred Names
prostaglandin F2 receptor negative regulator
Names
CD9 partner 1
glu-Trp-Ile EWI motif-containing protein F
prostaglandin F2-alpha receptor regulatory protein
prostaglandin F2-alpha receptor-associated protein

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_011197.3NP_035327.2  prostaglandin F2 receptor negative regulator precursor

    See identical proteins and their annotated locations for NP_035327.2

    Status: VALIDATED

    Source sequence(s)
    AL645930, AL669872
    Consensus CDS
    CCDS17680.1
    UniProtKB/Swiss-Prot
    Q5SRA8, Q9WV91
    UniProtKB/TrEMBL
    Q69ZJ6
    Related
    ENSMUSP00000099755.4, ENSMUST00000102694.4
    Conserved Domains (3) summary
    smart00406
    Location:39121
    IGv; Immunoglobulin V-Type
    smart00410
    Location:29140
    IG_like; Immunoglobulin like
    cl11960
    Location:283375
    Ig; Immunoglobulin domain

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000069.7 Reference GRCm39 C57BL/6J

    Range
    100947546..101018061 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_017319503.2XP_017174992.1  prostaglandin F2 receptor negative regulator isoform X1

    UniProtKB/TrEMBL
    Q69ZJ6
    Conserved Domains (2) summary
    smart00406
    Location:36118
    IGv; Immunoglobulin V-Type
    smart00409
    Location:281372
    IG; Immunoglobulin
  2. XM_006501147.4XP_006501210.1  prostaglandin F2 receptor negative regulator isoform X2

    See identical proteins and their annotated locations for XP_006501210.1

    UniProtKB/TrEMBL
    Q69ZJ6
    Conserved Domains (2) summary
    smart00406
    Location:27109
    IGv; Immunoglobulin V-Type
    smart00409
    Location:272363
    IG; Immunoglobulin