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Ptgfr prostaglandin F receptor [ Mus musculus (house mouse) ]

Gene ID: 19220, updated on 5-Mar-2024

Summary

Official Symbol
Ptgfrprovided by MGI
Official Full Name
prostaglandin F receptorprovided by MGI
Primary source
MGI:MGI:97796
See related
Ensembl:ENSMUSG00000028036 AllianceGenome:MGI:97796
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
fp; PGF
Summary
Predicted to enable prostaglandin F receptor activity. Involved in positive regulation of gene expression and response to estradiol. Acts upstream of or within negative regulation of apoptotic process and response to lipopolysaccharide. Predicted to be located in cytoplasm. Predicted to be active in plasma membrane. Is expressed in cloaca; genital tubercle; jaw; and viscerocranium. Orthologous to human PTGFR (prostaglandin F receptor). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in ovary adult (RPKM 14.0), heart adult (RPKM 2.7) and 5 other tissues See more
Orthologs
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Genomic context

See Ptgfr in Genome Data Viewer
Location:
3 H3; 3 76.96 cM
Exon count:
3
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 3 NC_000069.7 (151504247..151543165, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 3 NC_000069.6 (151798610..151837528, complement)

Chromosome 3 - NC_000069.7Genomic Context describing neighboring genes Neighboring gene interferon-induced protein 44 Neighboring gene interferon-induced protein 44 like Neighboring gene STARR-seq mESC enhancer starr_09276 Neighboring gene predicted gene, 31596 Neighboring gene predicted gene, 25056

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)

Pathways from PubChem

General gene information

Markers

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables G protein-coupled receptor activity IEA
Inferred from Electronic Annotation
more info
 
enables prostaglandin F receptor activity IBA
Inferred from Biological aspect of Ancestor
more info
 
enables prostaglandin F receptor activity ISO
Inferred from Sequence Orthology
more info
 
enables prostaglandin receptor activity IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
located_in cytoplasm ISO
Inferred from Sequence Orthology
more info
 
located_in membrane IEA
Inferred from Electronic Annotation
more info
 
is_active_in plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in plasma membrane ISO
Inferred from Sequence Orthology
more info
 

General protein information

Preferred Names
prostaglandin F2-alpha receptor
Names
PGF receptor
PGF2-alpha receptor
prostaglandin F2alpha receptor
prostanoid FP receptor

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_008966.3NP_032992.1  prostaglandin F2-alpha receptor

    See identical proteins and their annotated locations for NP_032992.1

    Status: VALIDATED

    Source sequence(s)
    AK080620, AK086563, AK141760, BB613784
    Consensus CDS
    CCDS17913.1
    UniProtKB/Swiss-Prot
    P43117
    UniProtKB/TrEMBL
    Q60I90, Q9D627
    Related
    ENSMUSP00000029670.6, ENSMUST00000029670.7
    Conserved Domains (1) summary
    pfam00001
    Location:44304
    7tm_1; 7 transmembrane receptor (rhodopsin family)

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000069.7 Reference GRCm39 C57BL/6J

    Range
    151504247..151543165 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)