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Med9 mediator complex subunit 9 [ Mus musculus (house mouse) ]

Gene ID: 192191, updated on 8-Dec-2022

Summary

Official Symbol
Med9provided by MGI
Official Full Name
mediator complex subunit 9provided by MGI
Primary source
MGI:MGI:2183151
See related
Ensembl:ENSMUSG00000061650 AllianceGenome:MGI:2183151
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Med25
Summary
Predicted to enable transcription coregulator activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Part of mediator complex. Orthologous to human MED9 (mediator complex subunit 9). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in testis adult (RPKM 21.0), adrenal adult (RPKM 15.3) and 28 other tissues See more
Orthologs
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Genomic context

See Med9 in Genome Data Viewer
Location:
11; 11 B1.3
Exon count:
2
Annotation release Status Assembly Chr Location
109 current GRCm39 (GCF_000001635.27) 11 NC_000077.7 (59839040..59854132)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 11 NC_000077.6 (59948214..59963306)

Chromosome 11 - NC_000077.7Genomic Context describing neighboring genes Neighboring gene predicted gene, 51900 Neighboring gene mediator complex subunit 9, opposite strand Neighboring gene RAS, dexamethasone-induced 1 Neighboring gene phosphatidylethanolamine N-methyltransferase Neighboring gene predicted gene, 53709 Neighboring gene predicted gene, 38498

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (1) 

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • FLJ10193, MGC30366

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
enables transcription coregulator activity IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
part_of core mediator complex ISO
Inferred from Sequence Orthology
more info
 
part_of mediator complex IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
part_of mediator complex IDA
Inferred from Direct Assay
more info
PubMed 
located_in nucleoplasm TAS
Traceable Author Statement
more info
 
located_in nucleus ISO
Inferred from Sequence Orthology
more info
 

General protein information

Preferred Names
mediator of RNA polymerase II transcription subunit 9
Names
mediator of RNA polymerase II transcription, subunit 9 homolog

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_138675.3NP_619616.2  mediator of RNA polymerase II transcription subunit 9

    See identical proteins and their annotated locations for NP_619616.2

    Status: VALIDATED

    Source sequence(s)
    AL603710, BY295874
    Consensus CDS
    CCDS24780.1
    UniProtKB/Swiss-Prot
    Q8R5H4, Q8VCS6
    Related
    ENSMUSP00000080641.7, ENSMUST00000081980.7
    Conserved Domains (1) summary
    pfam07544
    Location:60132
    Med9; RNA polymerase II transcription mediator complex subunit 9

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000077.7 Reference GRCm39 C57BL/6J

    Range
    59839040..59854132
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)