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Ptcra pre T cell antigen receptor alpha [ Mus musculus (house mouse) ]

Gene ID: 19208, updated on 8-Feb-2024

Summary

Official Symbol
Ptcraprovided by MGI
Official Full Name
pre T cell antigen receptor alphaprovided by MGI
Primary source
MGI:MGI:104857
See related
Ensembl:ENSMUSG00000036858 AllianceGenome:MGI:104857
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
pTa; gp33; pT[a]; pTalpha; pT-alpha; pT-alpha-TCR
Summary
Acts upstream of or within negative regulation of thymocyte apoptotic process. Predicted to be located in plasma membrane. Is expressed in thymus and thymus primordium. Orthologous to human PTCRA (pre T cell antigen receptor alpha). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Restricted expression toward thymus adult (RPKM 45.7) See more
Orthologs
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Genomic context

See Ptcra in Genome Data Viewer
Location:
17 C; 17 22.9 cM
Exon count:
4
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 17 NC_000083.7 (47066589..47074659, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 17 NC_000083.6 (46755663..46763712, complement)

Chromosome 17 - NC_000083.7Genomic Context describing neighboring genes Neighboring gene glycine N-methyltransferase Neighboring gene canopy FGF signaling regulator 3 Neighboring gene STARR-positive B cell enhancer ABC_E2490 Neighboring gene STARR-positive B cell enhancer ABC_E3204 Neighboring gene CapStarr-seq enhancer MGSCv37_chr17:46900557-46900758 Neighboring gene RIKEN cDNA 2310039H08 gene Neighboring gene ribosomal protein L7-like 1 Neighboring gene STARR-positive B cell enhancer ABC_E7539

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Targeted (5)  1 citation
  • Endonuclease-mediated (2) 

Pathways from PubChem

General gene information

Markers

Gene Ontology Provided by MGI

Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
 
located_in plasma membrane TAS
Traceable Author Statement
more info
 

General protein information

Preferred Names
pre T-cell antigen receptor alpha

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_011195.3NP_035325.2  pre T-cell antigen receptor alpha precursor

    Status: VALIDATED

    Source sequence(s)
    CT030702
    Consensus CDS
    CCDS28840.1
    UniProtKB/Swiss-Prot
    P0C6B2
    UniProtKB/TrEMBL
    A0A0R4J0F4
    Related
    ENSMUSP00000035683.9, ENSMUST00000041012.9

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000083.7 Reference GRCm39 C57BL/6J

    Range
    47066589..47074659 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)