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Prl6a1 prolactin family 6, subfamily a, member 1 [ Mus musculus (house mouse) ]

Gene ID: 19111, updated on 12-Aug-2019

Summary

Official Symbol
Prl6a1provided by MGI
Official Full Name
prolactin family 6, subfamily a, member 1provided by MGI
Primary source
MGI:MGI:1206579
See related
Ensembl:ENSMUSG00000069259
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Ghd10; PLP-B; Prlpb
Expression
Restricted expression toward placenta adult (RPKM 66.5) See more

Genomic context

See Prl6a1 in Genome Data Viewer
Location:
13 A3.1; 13 12.39 cM
Exon count:
5
Annotation release Status Assembly Chr Location
108 current GRCm38.p6 (GCF_000001635.26) 13 NC_000079.6 (27312560..27319254)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 13 NC_000079.5 (27404496..27411121)

Chromosome 13 - NC_000079.6Genomic Context describing neighboring genes Neighboring gene prolactin family 3, subfamily b, member 1 Neighboring gene prolactin family 3, subfamily a, member 1 Neighboring gene craniofacial development protein 1 pseudogene Neighboring gene prolactin family 8, subfamily a, member 2 Neighboring gene prolactin family 2, subfamily b, member 1

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Pathways from BioSystems

General gene information

Markers

Gene Ontology Provided by MGI

Function Evidence Code Pubs
hormone activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
prolactin receptor binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Process Evidence Code Pubs
female pregnancy IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
mammary gland development IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
positive regulation of JAK-STAT cascade IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
positive regulation of cell proliferation IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
positive regulation of lactation IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
response to nutrient levels IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Component Evidence Code Pubs
extracellular region IEA
Inferred from Electronic Annotation
more info
 
extracellular space IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 

General protein information

Preferred Names
prolactin-6A1
Names
PRL-like protein B
growth hormone d10
placental prolactin-like protein B
prolactin-like protein B

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_011166.2NP_035296.1  prolactin-6A1 precursor

    See identical proteins and their annotated locations for NP_035296.1

    Status: VALIDATED

    Source sequence(s)
    AF015563
    Consensus CDS
    CCDS26395.1
    UniProtKB/Swiss-Prot
    O35257
    UniProtKB/TrEMBL
    A0A0M6L0L9
    Related
    ENSMUSP00000089269.2, ENSMUST00000091680.8
    Conserved Domains (1) summary
    cd10288
    Location:30230
    prolactin_like; Prolactin (PRL or PRL1), chorionic somatomammotropin, and related pituitary gland hormones

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 108 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm38.p6 C57BL/6J

Genomic

  1. NC_000079.6 Reference GRCm38.p6 C57BL/6J

    Range
    27312560..27319254
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_017315424.2XP_017170913.1  prolactin-6A1 isoform X1

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