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Y54F10AR.1 Phosphatidylinositol transfer protein [ Caenorhabditis elegans ]

Gene ID: 190268, updated on 2-Nov-2024

Summary

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Official Symbol
Y54F10AR.1
Official Full Name
Phosphatidylinositol transfer protein
Primary source
WormBase:WBGene00021854
Locus tag
CELE_Y54F10AR.1
See related
AllianceGenome:WB:WBGene00021854
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to enable phospholipid binding activity and phospholipid transporter activity. Predicted to be involved in intermembrane lipid transfer and phospholipid transport. Predicted to be active in cytoplasm. Orthologous to several human genes including PITPNA (phosphatidylinositol transfer protein alpha). [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See Y54F10AR.1 in Genome Data Viewer
Location:
chromosome: III
Exon count:
5
Sequence:
Chromosome: III; NC_003281.10 (2572158..2575685, complement)

Chromosome III - NC_003281.10Genomic Context describing neighboring genes Neighboring gene BTB domain-containing protein Neighboring gene Nuclear receptor domain-containing protein Neighboring gene Mitochondrial genome maintenance exonuclease 1 Neighboring gene FTH domain-containing protein Neighboring gene AP complex subunit beta Neighboring gene G Protein, Alpha subunit

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003281.10

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Depletion of endogenously biotinylated carboxylases enhances the sensitivity of TurboID-mediated proximity labeling in Caenorhabditis elegans. Artan M, et al. J Biol Chem, 2022 Sep. PMID 35933017, Free PMC Article
  2. Interactome analysis of Caenorhabditis elegans synapses by TurboID-based proximity labeling. Artan M, et al. J Biol Chem, 2021 Sep. PMID 34416233, Free PMC Article
  3. EPIC: software toolkit for elution profile-based inference of protein complexes. Hu LZ, et al. Nat Methods, 2019 Aug. PMID 31308550, Free PMC Article
  4. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
enables phosphatidylcholine binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables phosphatidylcholine transporter activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables phosphatidylinositol binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables phosphatidylinositol transfer activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables phospholipid transporter activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in intermembrane lipid transfer IEA
Inferred from Electronic Annotation
more info
  
involved_in phospholipid transport IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
Phosphatidylinositol transfer protein
NP_497582.3
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003281.10 Reference assembly

    Range
    2572158..2575685 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_065181.6 → NP_497582.3  Phosphatidylinositol transfer protein [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_497582.3

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q965T2
    Conserved Domains (1) summary
    cl14643
    Location:2 → 261
    SRPBCC; START/RHO_alpha_C/PITP/Bet_v1/CoxG/CalC (SRPBCC) ligand-binding domain superfamily
Nucleotide Protein
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