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aat-9 Amino acid transporter [ Caenorhabditis elegans ]

Gene ID: 190250, updated on 23-Nov-2023

Summary

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Gene symbol
aat-9
Gene description
Amino acid transporter
Primary source
WormBase:WBGene00000010
Locus tag
CELE_Y53H1C.1
See related
AllianceGenome:WB:WBGene00000010
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to enable L-amino acid transmembrane transporter activity. Predicted to be involved in amino acid transmembrane transport. Located in cell surface. Is expressed in body wall musculature and neurons. Orthologous to several human genes including SLC7A10 (solute carrier family 7 member 10); SLC7A11 (solute carrier family 7 member 11); and SLC7A5 (solute carrier family 7 member 5). [provided by Alliance of Genome Resources, Apr 2022]
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Genomic context

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Location:
chromosome: I
Exon count:
12
Sequence:
Chromosome: I; NC_003279.8 (11388682..11396662, complement)

Chromosome I - NC_003279.8Genomic Context describing neighboring genes Neighboring gene U1-type domain-containing protein Neighboring gene Peptide-N(4)-(N-acetyl-beta-glucosaminyl)asparagine amidase Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene BRO1 domain-containing protein Neighboring gene ncRNA Neighboring gene protein of unknown function WSN domain-containing protein

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003279.8

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Aromatic amino acid transporter AAT-9 of Caenorhabditis elegans localizes to neurons and muscle cells. Veljkovic E, et al. J Biol Chem, 2004 Nov 19. PMID 15364921
  2. Functional characterization of Caenorhabditis elegans heteromeric amino acid transporters. Veljkovic E, et al. J Biol Chem, 2004 Feb 27. PMID 14668347
  3. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916
  4. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. AAT-9 is expressed in excitable cells of the nematode head and pharynx in which it may provide a pathway for aromatic amino acid transport
    Title: Aromatic amino acid transporter AAT-9 of Caenorhabditis elegans localizes to neurons and muscle cells.
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General gene information

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Markers

Homology

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
enables L-amino acid transmembrane transporter activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables transmembrane transporter activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in L-alpha-amino acid transmembrane transport IEA
Inferred from Electronic Annotation
more info
  
involved_in amino acid transmembrane transport IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in transmembrane transport IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in cell surface IDA
Inferred from Direct Assay
more info
 PubMed 
located_in membrane IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
Amino acid transporter
NP_001021788.1
  • Confirmed by transcript evidence
NP_001021789.1
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003279.8 Reference assembly

    Range
    11388682..11396662 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001026618.5 → NP_001021789.1  Amino acid transporter [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_001021789.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q56VY0
    Conserved Domains (1) summary
    TIGR00911
    Location:19 → 477
    2A0308; L-type amino acid transporter

  2. NM_001026617.5 → NP_001021788.1  Amino acid transporter [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_001021788.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q9NA91
    Conserved Domains (1) summary
    TIGR00911
    Location:19 → 477
    2A0308; L-type amino acid transporter
Nucleotide Protein
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