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Y50D7A.3 Protein kinase domain-containing protein;phosphorylase kinase [ Caenorhabditis elegans ]

Gene ID: 190101, updated on 4-Jan-2025

Summary

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Official Symbol
Y50D7A.3
Official Full Name
Protein kinase domain-containing protein;phosphorylase kinase
Primary source
WormBase:WBGene00021753
Locus tag
CELE_Y50D7A.3
See related
AllianceGenome:WB:WBGene00021753
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to enable phosphorylase kinase activity. Predicted to be involved in glycogen metabolic process and signal transduction. Predicted to be part of phosphorylase kinase complex. Predicted to be active in cytoplasm. Human ortholog(s) of this gene implicated in glycogen storage disease; glycogen storage disease IXc; and liver cirrhosis. Orthologous to several human genes including PHKG2 (phosphorylase kinase catalytic subunit gamma 2). [provided by Alliance of Genome Resources, Jan 2025]
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Genomic context

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See Y50D7A.3 in Genome Data Viewer
Location:
chromosome: III
Exon count:
7
Sequence:
Chromosome: III; NC_003281.10 (254535..264892)

Chromosome III - NC_003281.10Genomic Context describing neighboring genes Neighboring gene N-alpha-acetyltransferase 16, NatA auxiliary subunit Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene DNA 5'-3' helicase Neighboring gene ncRNA Neighboring gene Transcriptional regulatory protein

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003281.10

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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General gene information

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Homology

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
  
enables calmodulin binding IEA
Inferred from Electronic Annotation
more info
  
enables kinase activity IEA
Inferred from Electronic Annotation
more info
  
enables phosphorylase kinase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables phosphorylase kinase activity IEA
Inferred from Electronic Annotation
more info
  
enables protein kinase activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in glycogen biosynthetic process IEA
Inferred from Electronic Annotation
more info
  
involved_in glycogen metabolic process IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in glycogen metabolic process IEA
Inferred from Electronic Annotation
more info
  
involved_in protein phosphorylation IEA
Inferred from Electronic Annotation
more info
  
involved_in signal transduction IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
  
part_of phosphorylase kinase complex IBA
Inferred from Biological aspect of Ancestor
more info
  
part_of phosphorylase kinase complex IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
Protein kinase domain-containing protein;phosphorylase kinase
NP_001360127.1
  • Confirmed by transcript evidence
NP_001368037.1
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003281.10 Reference assembly

    Range
    254535..264892
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001381687.3 → NP_001368037.1  phosphorylase kinase [Caenorhabditis elegans]

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q9N3L4
    Conserved Domains (1) summary
    cd14093
    Location:27 → 298
    STKc_PhKG; Catalytic domain of the Serine/Threonine Kinase, Phosphorylase kinase Gamma subunit

  2. NM_001373828.3 → NP_001360127.1  Protein kinase domain-containing protein [Caenorhabditis elegans]

    Status: REVIEWED

    UniProtKB/TrEMBL
    H2L0P0
    Conserved Domains (1) summary
    cl21453
    Location:27 → 97
    PKc_like; Protein Kinases, catalytic domain
Nucleotide Protein
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