U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

dgtr-1 Acyltransferase [ Caenorhabditis elegans ]

Gene ID: 189077, updated on 4-Jan-2025

Summary

Go to the top of the page Help
Official Symbol
dgtr-1
Official Full Name
Acyltransferase
Primary source
WormBase:WBGene00020910
Locus tag
CELE_W01A11.2
See related
AllianceGenome:WB:WBGene00020910
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to enable diacylglycerol O-acyltransferase activity. Predicted to be involved in triglyceride biosynthetic process. Located in sarcoplasmic reticulum. Is expressed in nervous system. Human ortholog(s) of this gene implicated in metabolic dysfunction-associated steatotic liver disease. Orthologous to several human genes including MOGAT1 (monoacylglycerol O-acyltransferase 1). [provided by Alliance of Genome Resources, Jan 2025]
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
See dgtr-1 in Genome Data Viewer
Location:
chromosome: V
Exon count:
5
Sequence:
Chromosome: V; NC_003283.11 (6497108..6498484)

Chromosome V - NC_003283.11Genomic Context describing neighboring genes Neighboring gene Galectin Neighboring gene Choline/carnitine acyltransferase domain-containing protein Neighboring gene ncRNA Neighboring gene Epoxide hydrolase;Microsomal epoxide hydrolase Neighboring gene molybdopterin molybdotransferase Neighboring gene DUF2382 domain-containing protein

Genomic regions, transcripts, and products

Go to the top of the page Help
Genomic Sequence:
NC_003283.11

Go to nucleotide: Graphics FASTA GenBank

Bibliography

Go to the top of the pageHelp

Related articles in PubMed

  1. Hierarchical assembly of the eggshell and permeability barrier in C. elegans. Olson SK, et al. J Cell Biol, 2012 Aug 20. PMID 22908315, Free PMC Article
  2. Identification and analysis of internal promoters in Caenorhabditis elegans operons. Huang P, et al. Genome Res, 2007 Oct. PMID 17712020, Free PMC Article
  3. High-throughput in vivo analysis of gene expression in Caenorhabditis elegans. Hunt-Newbury R, et al. PLoS Biol, 2007 Sep. PMID 17850180, Free PMC Article
  4. Determining the sub-cellular localization of proteins within Caenorhabditis elegans body wall muscle. Meissner B, et al. PLoS One, 2011. PMID 21611156, Free PMC Article
  5. Comparative genomics and functional study of lipid metabolic genes in Caenorhabditis elegans. Zhang Y, et al. BMC Genomics, 2013 Mar 12. PMID 23496871, Free PMC Article

See all (9) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

Go to the top of the page Help
Products Interactant Other Gene Complex Source Pubs Description

General gene information

Go to the top of the page Help

Markers

Homology

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
enables O-acyltransferase activity IEA
Inferred from Electronic Annotation
more info
  
enables acyltransferase activity IEA
Inferred from Electronic Annotation
more info
  
enables diacylglycerol O-acyltransferase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
involved_in triglyceride biosynthetic process IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
located_in endoplasmic reticulum IEA
Inferred from Electronic Annotation
more info
  
is_active_in endoplasmic reticulum membrane IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in endoplasmic reticulum membrane IEA
Inferred from Electronic Annotation
more info
  
located_in membrane IEA
Inferred from Electronic Annotation
more info
  
located_in sarcoplasmic reticulum HDA PubMed 

General protein information

Go to the top of the page Help
Preferred Names
Acyltransferase
NP_504649.1
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003283.11 Reference assembly

    Range
    6497108..6498484
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_072248.6 → NP_504649.1  Acyltransferase [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_504649.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q23067
    Conserved Domains (1) summary
    pfam03982
    Location:63 → 359
    DAGAT; Diacylglycerol acyltransferase
Nucleotide Protein
Heading Accession and Version

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

Molecular Biology Databases
Research Materials
Tools
Miscellaneous