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neto-1 CUB domain-containing protein [ Caenorhabditis elegans ]

Gene ID: 186950, updated on 2-Dec-2025
Official Symbol
neto-1
Official Full Name
CUB domain-containing protein
Primary source
WormBase:WBGene00019360
Locus tag
CELE_K03E5.1
See related
AllianceGenome:WB:WBGene00019360
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to be located in membrane. Orthologous to human NETO1 (neuropilin and tolloid like 1) and NETO2 (neuropilin and tolloid like 2). [provided by Alliance of Genome Resources, Jul 2025]
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Location:
chromosome: I
Exon count:
10
Sequence:
Chromosome: I; NC_003279.8 (3427148..3433207)

Chromosome I - NC_003279.8Genomic Context describing neighboring genes Neighboring gene Cyclin-dependent kinase 2;cyclin-dependent kinase Neighboring gene ncRNA Neighboring gene CaLponIn-liKe proteins Neighboring gene Separin homolog sep-1 Neighboring gene non-specific serine/threonine protein kinase Neighboring gene Protein kinase domain-containing protein Neighboring gene DNA mismatch repair protein

Genomic Sequence:
NC_003279.8

Go to nucleotide: Graphics FASTA GenBank

Related articles in PubMed

  1. Screening for cold tolerance genes in C. elegans, whose expressions are affected by anticancer drugs camptothecin and leptomycin B. Okahata M, et al. Sci Rep, 2024 Mar 5. PMID 38443452, Free PMC Article
  2. OrthoList: a compendium of C. elegans genes with human orthologs. Shaye DD, et al. PLoS One, 2011. PMID 21647448, Free PMC Article
  3. OrthoList 2: A New Comparative Genomic Analysis of Human and Caenorhabditis elegans Genes. Kim W, et al. Genetics, 2018 Oct. PMID 30120140, Free PMC Article
  4. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

GeneRIFs: Gene References Into Functions

Markers

Homology

Preferred Names
CUB domain-containing protein
NP_491159.3
  • Confirmed by transcript evidence

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003279.8 Reference assembly

    Range
    3427148..3433207
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_058758.5 → NP_491159.3  CUB domain-containing protein

    See identical proteins and their annotated locations for NP_491159.3

    Status: REVIEWED

    UniProtKB/TrEMBL
    G4SMJ0, O61849
    Conserved Domains (2) summary
    cd00041
    Location:39 → 147
    CUB; CUB domain; extracellular domain; present in proteins mostly known to be involved in development; not found in prokaryotes, plants and yeast.
    cd00112
    Location:291 → 320
    LDLa; Low Density Lipoprotein Receptor Class A domain, a cysteine-rich repeat that plays a central role in mammalian cholesterol metabolism; the receptor protein binds LDL and transports it into cells by endocytosis; 7 successive cysteine-rich repeats of about ...
Nucleotide Protein
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