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Phka1 phosphorylase kinase alpha 1 [ Mus musculus (house mouse) ]

Gene ID: 18679, updated on 12-Aug-2019

Summary

Official Symbol
Phka1provided by MGI
Official Full Name
phosphorylase kinase alpha 1provided by MGI
Primary source
MGI:MGI:97576
See related
Ensembl:ENSMUSG00000034055
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Phka; 5330411D17; 9830108K24Rik
Expression
Ubiquitous expression in mammary gland adult (RPKM 5.2), cerebellum adult (RPKM 3.0) and 28 other tissues See more
Orthologs

Genomic context

See Phka1 in Genome Data Viewer
Location:
X D; X 45.47 cM
Exon count:
34
Annotation release Status Assembly Chr Location
108 current GRCm38.p6 (GCF_000001635.26) X NC_000086.7 (102513975..102644301, complement)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) X NC_000086.6 (99709314..99839585, complement)

Chromosome X - NC_000086.7Genomic Context describing neighboring genes Neighboring gene predicted gene 14858 Neighboring gene histone deacetylase 8 Neighboring gene predicted gene, 32262 Neighboring gene high mobility group box 1 pseudogene Neighboring gene transcriptional adaptor 3 pseudogene

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Spontaneous (1)  1 citation
  • Endonuclease-mediated (1) 

Pathways from PubChem

General gene information

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
calmodulin binding IEA
Inferred from Electronic Annotation
more info
 
catalytic activity IEA
Inferred from Electronic Annotation
more info
 
contributes_to phosphorylase kinase activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
contributes_to phosphorylase kinase activity ISO
Inferred from Sequence Orthology
more info
 
Process Evidence Code Pubs
carbohydrate metabolic process IEA
Inferred from Electronic Annotation
more info
 
glycogen metabolic process IEA
Inferred from Electronic Annotation
more info
 
protein autophosphorylation ISO
Inferred from Sequence Orthology
more info
 
Component Evidence Code Pubs
membrane IEA
Inferred from Electronic Annotation
more info
 
phosphorylase kinase complex IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
phosphorylase kinase complex ISO
Inferred from Sequence Orthology
more info
 
plasma membrane IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
phosphorylase b kinase regulatory subunit alpha, skeletal muscle isoform
Names
phosphorylase kinase alpha M subunit
NP_032858.2
NP_766609.2
XP_006527957.1
XP_006527958.1
XP_017173916.1

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_008832.2NP_032858.2  phosphorylase b kinase regulatory subunit alpha, skeletal muscle isoform isoform 1

    See identical proteins and their annotated locations for NP_032858.2

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) encodes the longer isoform (1).
    Source sequence(s)
    AL732405, AL805925
    Consensus CDS
    CCDS30323.1
    UniProtKB/Swiss-Prot
    P18826
    Related
    ENSMUSP00000061991.7, ENSMUST00000052012.13
    Conserved Domains (1) summary
    pfam00723
    Location:8439
    Glyco_hydro_15; Glycosyl hydrolases family 15
  2. NM_173021.3NP_766609.2  phosphorylase b kinase regulatory subunit alpha, skeletal muscle isoform isoform 2

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) lacks an exon in the coding region, compared to variant 1. The encoded isoform (2) is shorter, compared to isoform 1.
    Source sequence(s)
    AK036440, AK137497, AK163548, BB662994, BY414985
    Consensus CDS
    CCDS30324.1
    UniProtKB/TrEMBL
    A2AI91, Q3TQJ0, Q3UV91, Q8CBA7
    Related
    ENSMUSP00000042778.5, ENSMUST00000043596.11
    Conserved Domains (1) summary
    pfam00723
    Location:8439
    Glyco_hydro_15; Glycosyl hydrolases family 15

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 108 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm38.p6 C57BL/6J

Genomic

  1. NC_000086.7 Reference GRCm38.p6 C57BL/6J

    Range
    102513975..102644301 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006527894.4XP_006527957.1  phosphorylase b kinase regulatory subunit alpha, skeletal muscle isoform isoform X1

    Related
    ENSMUSP00000112529.1, ENSMUST00000122022.7
    Conserved Domains (1) summary
    pfam00723
    Location:8439
    Glyco_hydro_15; Glycosyl hydrolases family 15
  2. XM_006527895.4XP_006527958.1  phosphorylase b kinase regulatory subunit alpha, skeletal muscle isoform isoform X2

    Conserved Domains (1) summary
    pfam00723
    Location:8439
    Glyco_hydro_15; Glycosyl hydrolases family 15
  3. XM_017318427.2XP_017173916.1  phosphorylase b kinase regulatory subunit alpha, skeletal muscle isoform isoform X3

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