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klo-2 Glycoside hydrolase family 1 protein [ Caenorhabditis elegans ]

Gene ID: 184000, updated on 2-Nov-2024

Summary

Official Symbol
klo-2
Official Full Name
Glycoside hydrolase family 1 protein
Primary source
WormBase:WBGene00017103
Locus tag
CELE_E02H9.5
See related
AllianceGenome:WB:WBGene00017103
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to enable beta-glucosidase activity. Predicted to be involved in carbohydrate metabolic process. Is expressed in hypodermis and intestine. Used to study kidney disease. Human ortholog(s) of this gene implicated in congenital lactase deficiency; coronary artery disease; intracranial embolism; and spondylosis. Orthologous to several human genes including GBA3 (glucosylceramidase beta 3 (gene/pseudogene)) and LCTL (lactase like). [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

See klo-2 in Genome Data Viewer
Location:
chromosome: III
Exon count:
7
Sequence:
Chromosome: III; NC_003281.10 (2446209..2448696)

Chromosome III - NC_003281.10Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene Secreted protein Neighboring gene Nuclear hormone receptor family member nhr-121 Neighboring gene pseudo

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General protein information

Preferred Names
Glycoside hydrolase family 1 protein
NP_001367723.1
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003281.10 Reference assembly

    Range
    2446209..2448696
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001381778.1NP_001367723.1  Glycoside hydrolase family 1 protein [Caenorhabditis elegans]

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q9TZA0
    Conserved Domains (1) summary
    cl23725
    Location:7467
    Glyco_hydro; Glycosyl hydrolases