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Olfr57 olfactory receptor 57 [ Mus musculus (house mouse) ]

Gene ID: 18357, updated on 25-Sep-2020

Summary

Official Symbol
Olfr57provided by MGI
Official Full Name
olfactory receptor 57provided by MGI
Primary source
MGI:MGI:1333808
See related
Ensembl:ENSMUSG00000060205
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
IF1; IF12; MOR139; MOR139-3
Summary
Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. [provided by RefSeq, Jul 2008]

Genomic context

See Olfr57 in Genome Data Viewer
Location:
10; 10 C1
Exon count:
1
Annotation release Status Assembly Chr Location
109 current GRCm39 (GCF_000001635.27) 10 NC_000076.7 (78870557..78871636)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 10 NC_000076.6 (79034723..79035802)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 10 NC_000076.5 (78497468..78498547)

Chromosome 10 - NC_000076.7Genomic Context describing neighboring genes Neighboring gene olfactory receptor 1352 Neighboring gene olfactory receptor 1351 Neighboring gene predicted gene, 40712 Neighboring gene RIKEN cDNA 2610008E11 gene Neighboring gene vomeronasal 2, receptor 80

Genomic regions, transcripts, and products

Pathways from PubChem

General gene information

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
olfactory receptor activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
olfactory receptor activity ISA
Inferred from Sequence Alignment
more info
PubMed 
Process Evidence Code Pubs
G protein-coupled receptor signaling pathway ISA
Inferred from Sequence Alignment
more info
PubMed 
sensory perception of smell ISA
Inferred from Sequence Alignment
more info
PubMed 
Component Evidence Code Pubs
integral component of membrane ISA
Inferred from Sequence Alignment
more info
PubMed 

General protein information

Preferred Names
olfactory receptor 57
Names
GA_x6K02T2QGN0-2777431-2776472
olfactory receptor MOR139-3
olfactory receptor OR6-8

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_147041.2NP_667252.1  olfactory receptor 57

    See identical proteins and their annotated locations for NP_667252.1

    Status: VALIDATED

    Source sequence(s)
    AC158798
    Consensus CDS
    CCDS23975.1
    UniProtKB/TrEMBL
    Q8VGU7
    Related
    ENSMUSP00000080872.2, ENSMUST00000082244.2
    Conserved Domains (2) summary
    pfam00001
    Location:42291
    7tm_1; 7 transmembrane receptor (rhodopsin family)
    cl21561
    Location:32306
    7tm_4; Olfactory receptor

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000076.7 Reference GRCm39 C57BL/6J

    Range
    78870557..78871636
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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