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cyp-34A6 CYtochrome P450 family [ Caenorhabditis elegans ]

Gene ID: 181848, updated on 18-Sep-2024

Summary

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Official Symbol
cyp-34A6
Official Full Name
CYtochrome P450 family
Primary source
WormBase:WBGene00015041
Locus tag
CELE_B0213.11
See related
AllianceGenome:WB:WBGene00015041
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to enable heme binding activity; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen; and steroid hydroxylase activity. Predicted to be involved in organic acid metabolic process and xenobiotic metabolic process. Predicted to be active in cytoplasm and intracellular membrane-bounded organelle. Human ortholog(s) of this gene implicated in hereditary spastic paraplegia 56. Orthologous to human CYP2U1 (cytochrome P450 family 2 subfamily U member 1). [provided by Alliance of Genome Resources, Apr 2022]
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Genomic context

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See cyp-34A6 in Genome Data Viewer
Location:
chromosome: V
Exon count:
7
Sequence:
Chromosome: V; NC_003283.11 (3958160..3961335, complement)

Chromosome V - NC_003283.11Genomic Context describing neighboring genes Neighboring gene Seven TM Receptor Neighboring gene CYtochrome P450 family Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene CYtochrome P450 family Neighboring gene ncRNA Neighboring gene CYtochrome P450 family Neighboring gene ncRNA

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003283.11

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. A map of the interactome network of the metazoan C. elegans. Li S, et al. Science, 2004 Jan 23. PMID 14704431, Free PMC Article
  2. OrthoList: a compendium of C. elegans genes with human orthologs. Shaye DD, et al. PLoS One, 2011. PMID 21647448, Free PMC Article
  3. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916
  4. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
enables heme binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables heme binding IEA
Inferred from Electronic Annotation
more info
  
enables iron ion binding IEA
Inferred from Electronic Annotation
more info
  
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
  
enables monooxygenase activity IEA
Inferred from Electronic Annotation
more info
  
enables oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen IEA
Inferred from Electronic Annotation
more info
  
enables oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen IBA
Inferred from Biological aspect of Ancestor
more info
  
enables steroid hydroxylase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
involved_in organic acid metabolic process IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in xenobiotic metabolic process IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
  
is_active_in intracellular membrane-bounded organelle IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
CYtochrome P450 family
NP_001256031.1
  • Confirmed by transcript evidence
NP_001317794.1
  • Confirmed by transcript evidence
NP_001380106.1
  • Product from WormBase gene class cyp;
    Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003283.11 Reference assembly

    Range
    3958160..3961335 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001269102.3 → NP_001256031.1  CYtochrome P450 family [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_001256031.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    O44656
    Conserved Domains (1) summary
    pfam00067
    Location:26 → 494
    p450; Cytochrome P450

  2. NM_001392497.1 → NP_001380106.1  CYtochrome P450 family [Caenorhabditis elegans]

    Status: REVIEWED

    UniProtKB/TrEMBL
    H1ZUV4
    Conserved Domains (1) summary
    cl41757
    Location:1 → 320
    cytochrome_P450; cytochrome P450 (CYP) superfamily

  3. NM_001330821.3 → NP_001317794.1  CYtochrome P450 family [Caenorhabditis elegans]

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A164D3C9
Nucleotide Protein
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