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vhl-1 von Hippel-Lindau tumor suppressor homolog [ Caenorhabditis elegans ]

Gene ID: 181321, updated on 28-May-2020

Summary

Gene symbol
vhl-1
Gene description
von Hippel-Lindau tumor suppressor homolog
Primary source
WormBase:WBGene00006922
Locus tag
CELE_F08G12.4
Gene type
protein coding
RNA name
von Hippel-Lindau tumor suppressor homolog
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis

Genomic context

See vhl-1 in Genome Data Viewer
Location:
chromosome: X
Exon count:
3
Sequence:
Chromosome: X; NC_003284.9 (11307356..11308518)

Chromosome X - NC_003284.9Genomic Context describing neighboring genes Neighboring gene WD_REPEATS_REGION domain-containing protein Neighboring gene hypothetical protein Neighboring gene hypothetical protein Neighboring gene RING-type domain-containing protein Neighboring gene hypothetical protein

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Gene Ontology Provided by WormBase

Process Evidence Code Pubs
protein ubiquitination IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
protein ubiquitination IEA
Inferred from Electronic Annotation
more info
 
response to hypoxia IMP
Inferred from Mutant Phenotype
more info
PubMed 
Component Evidence Code Pubs
Cul2-RING ubiquitin ligase complex IPI
Inferred from Physical Interaction
more info
PubMed 
VCB complex IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
nucleus IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 

General protein information

Preferred Names
von Hippel-Lindau tumor suppressor homolog
NP_509889.1
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003284.9 Reference assembly

    Range
    11307356..11308518
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_077488.6NP_509889.1  von Hippel-Lindau tumor suppressor homolog [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_509889.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q19213
    Conserved Domains (1) summary
    cd05468
    Location:19157
    pVHL; von Hippel-Landau (pVHL) tumor suppressor protein
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