U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Rrp1 ribosomal RNA processing 1 [ Mus musculus (house mouse) ]

Gene ID: 18114, updated on 30-Apr-2024

Summary

Official Symbol
Rrp1provided by MGI
Official Full Name
ribosomal RNA processing 1provided by MGI
Primary source
MGI:MGI:1203500
See related
Ensembl:ENSMUSG00000061032 AllianceGenome:MGI:1203500
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Nnp1; NNP-1
Summary
Predicted to be involved in rRNA processing. Predicted to be located in chromosome and nucleolus. Predicted to be part of preribosome, large subunit precursor. Predicted to be active in nucleus. Is expressed in several structures, including genitourinary system; gut; nervous system; sensory organ; and thymus. Orthologous to human RRP1 (ribosomal RNA processing 1). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in testis adult (RPKM 117.2), frontal lobe adult (RPKM 80.6) and 28 other tissues See more
Orthologs
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

See Rrp1 in Genome Data Viewer
Location:
10 C1; 10 39.72 cM
Exon count:
13
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 10 NC_000076.7 (78236196..78248877, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 10 NC_000076.6 (78400362..78413043, complement)

Chromosome 10 - NC_000076.7Genomic Context describing neighboring genes Neighboring gene predicted gene, 40709 Neighboring gene STARR-positive B cell enhancer ABC_E10623 Neighboring gene LSM7 homolog, U6 small nuclear RNA associated pseudogene Neighboring gene CapStarr-seq enhancer MGSCv37_chr10:77862123-77862306 Neighboring gene microRNA 6907 Neighboring gene cystatin B Neighboring gene microRNA 6410

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (3) 

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Gene Ontology Provided by MGI

Process Evidence Code Pubs
acts_upstream_of_or_within rRNA processing IEA
Inferred from Electronic Annotation
more info
 
involved_in rRNA processing IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
located_in chromosome ISO
Inferred from Sequence Orthology
more info
 
located_in nucleolus ISO
Inferred from Sequence Orthology
more info
 
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
 
part_of preribosome, small subunit precursor IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
ribosomal RNA processing protein 1 homolog A
Names
RRP1-like protein
novel nuclear protein 1
nucleolar protein Nop52
protein NNP-1
ribosomal RNA processing 1 homolog

NCBI Reference Sequences (RefSeq)

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_010925.3NP_035055.2  ribosomal RNA processing protein 1 homolog A

    See identical proteins and their annotated locations for NP_035055.2

    Status: VALIDATED

    Source sequence(s)
    AC160411
    Consensus CDS
    CCDS35961.1
    UniProtKB/Swiss-Prot
    O35712, P56183, Q9ERE1, Q9JI07, Q9JK67, Q9JKU2
    Related
    ENSMUSP00000058785.10, ENSMUST00000062678.11
    Conserved Domains (1) summary
    pfam05997
    Location:11218
    Nop52; Nucleolar protein,Nop52

RNA

  1. NR_190469.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AC160411
  2. NR_190470.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AC160411

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000076.7 Reference GRCm39 C57BL/6J

    Range
    78236196..78248877 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006513338.4XP_006513401.1  ribosomal RNA processing protein 1 homolog A isoform X1

    See identical proteins and their annotated locations for XP_006513401.1

    UniProtKB/TrEMBL
    Q05CN2
    Conserved Domains (2) summary
    pfam05997
    Location:1156
    Nop52; Nucleolar protein,Nop52
    cl30717
    Location:299424
    InfB; Translation initiation factor IF-2, a GTPase [Translation, ribosomal structure and biogenesis]