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sem-5 Sex muscle abnormal protein 5 [ Caenorhabditis elegans ]

Gene ID: 181055, updated on 10-Oct-2019

Summary

Gene symbol
sem-5
Gene description
Sex muscle abnormal protein 5
Primary source
WormBase:WBGene00004774
Locus tag
CELE_C14F5.5
Gene type
protein coding
RNA name
Sex muscle abnormal protein 5
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis

Genomic context

See sem-5 in Genome Data Viewer
Location:
chromosome: X
Exon count:
6
Sequence:
Chromosome: X; NC_003284.9 (7959452..7961723, complement)

Chromosome X - NC_003284.9Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene NIP3 homolog Neighboring gene Sidoreflexin Neighboring gene ncRNA Neighboring gene ncRNA

Bibliography

Pathways from BioSystems

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
SH3/SH2 adaptor activity ISS
Inferred from Sequence or Structural Similarity
more info
PubMed 
epidermal growth factor receptor binding IPI
Inferred from Physical Interaction
more info
PubMed 
protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Process Evidence Code Pubs
cell migration IMP
Inferred from Mutant Phenotype
more info
PubMed 
male genitalia development IMP
Inferred from Mutant Phenotype
more info
PubMed 
muscle organ development IMP
Inferred from Mutant Phenotype
more info
PubMed 
nematode larval development IMP
Inferred from Mutant Phenotype
more info
PubMed 
positive regulation of signal transduction IEA
Inferred from Electronic Annotation
more info
 
regulation of cell projection organization IMP
Inferred from Mutant Phenotype
more info
PubMed 
regulation of vulval development IMP
Inferred from Mutant Phenotype
more info
PubMed 
Component Evidence Code Pubs
membrane IEA
Inferred from Electronic Annotation
more info
 
plasma membrane IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
Sex muscle abnormal protein 5
NP_509342.1
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003284.9 Reference assembly

    Range
    7959452..7961723 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_076941.6NP_509342.1  Sex muscle abnormal protein 5 [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_509342.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    P29355
    Conserved Domains (3) summary
    cd09941
    Location:56151
    SH2_Grb2_like; Src homology 2 domain found in Growth factor receptor-bound protein 2 (Grb2) and similar proteins
    cd11804
    Location:253
    SH3_GRB2_like_N; N-terminal Src homology 3 domain of Growth factor receptor-bound protein 2 (GRB2) and related proteins
    cd11805
    Location:158210
    SH3_GRB2_like_C; C-terminal Src homology 3 domain of Growth factor receptor-bound protein 2 (GRB2) and related proteins
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