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unc-10 Rab-3-interacting molecule unc-10 [ Caenorhabditis elegans ]

Gene ID: 180990, updated on 5-Sep-2019

Summary

Gene symbol
unc-10
Gene description
Rab-3-interacting molecule unc-10
Primary source
WormBase:WBGene00006750
Locus tag
CELE_T10A3.1
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis

Genomic context

See unc-10 in Genome Data Viewer
Location:
chromosome: X
Exon count:
26
Sequence:
Chromosome: X; NC_003284.9 (7272334..7280322, complement)

Chromosome X - NC_003284.9Genomic Context describing neighboring genes Neighboring gene hypothetical protein Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene eLRR (extracellular Leucine-Rich Repeat) ONly

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

General gene information

Markers

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
Rab GTPase binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Rab GTPase binding IEA
Inferred from Electronic Annotation
more info
 
Rab GTPase binding IPI
Inferred from Physical Interaction
more info
PubMed 
ion channel binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
metal ion binding IEA
Inferred from Electronic Annotation
more info
 
protein C-terminus binding IPI
Inferred from Physical Interaction
more info
PubMed 
Process Evidence Code Pubs
calcium ion-regulated exocytosis of neurotransmitter IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
defecation IMP
Inferred from Mutant Phenotype
more info
PubMed 
exocytosis IEA
Inferred from Electronic Annotation
more info
 
locomotion IMP
Inferred from Mutant Phenotype
more info
PubMed 
locomotory behavior IMP
Inferred from Mutant Phenotype
more info
PubMed 
mating behavior IMP
Inferred from Mutant Phenotype
more info
PubMed 
positive regulation of multicellular organism growth IMP
Inferred from Mutant Phenotype
more info
PubMed 
positive regulation of synaptic transmission IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
positive regulation of synaptic transmission IDA
Inferred from Direct Assay
more info
PubMed 
positive regulation of synaptic transmission, cholinergic IMP
Inferred from Mutant Phenotype
more info
PubMed 
protein localization IMP
Inferred from Mutant Phenotype
more info
PubMed 
regulation of membrane potential IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
regulation of pharyngeal pumping IMP
Inferred from Mutant Phenotype
more info
PubMed 
regulation of synaptic plasticity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
regulation of synaptic vesicle exocytosis IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
synaptic transmission, cholinergic IMP
Inferred from Mutant Phenotype
more info
PubMed 
synaptic vesicle priming IDA
Inferred from Direct Assay
more info
PubMed 
Component Evidence Code Pubs
axon IDA
Inferred from Direct Assay
more info
PubMed 
cell junction IEA
Inferred from Electronic Annotation
more info
 
cytoskeleton of presynaptic active zone IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
membrane IEA
Inferred from Electronic Annotation
more info
 
presynaptic active zone IDA
Inferred from Direct Assay
more info
PubMed 
presynaptic active zone cytoplasmic component IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
presynaptic membrane IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
synapse IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
synapse IDA
Inferred from Direct Assay
more info
PubMed 
synapse IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
Rab-3-interacting molecule unc-10
NP_001024901.1
  • Confirmed by transcript evidence
NP_741831.1
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003284.9 Reference assembly

    Range
    7272334..7280322 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_171720.4NP_741831.1  Rab-3-interacting molecule unc-10 [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_741831.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q22366
    Conserved Domains (5) summary
    cd04028
    Location:14021548
    C2B_RIM1alpha; C2 domain second repeat contained in Rab3-interacting molecule (RIM) proteins
    cd04031
    Location:840963
    C2A_RIM1alpha; C2 domain first repeat contained in Rab3-interacting molecule (RIM) proteins
    COG0265
    Location:674755
    DegQ; Periplasmic serine protease, S1-C subfamily, contain C-terminal PDZ domain [Posttranslational modification, protein turnover, chaperones]
    cd00992
    Location:643731
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    cl22851
    Location:11130
    PHD_SF; PHD finger superfamily
  2. NM_001029730.4NP_001024901.1  Rab-3-interacting molecule unc-10 [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_001024901.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q22366
    Conserved Domains (4) summary
    cd04031
    Location:840963
    C2A_RIM1alpha; C2 domain first repeat contained in Rab3-interacting molecule (RIM) proteins
    COG0265
    Location:674755
    DegQ; Periplasmic serine protease, S1-C subfamily, contain C-terminal PDZ domain [Posttranslational modification, protein turnover, chaperones]
    cd00992
    Location:643731
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    cl22851
    Location:11130
    PHD_SF; PHD finger superfamily
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