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inx-3 Innexin-3 [ Caenorhabditis elegans ]

Gene ID: 180866, updated on 28-Oct-2024

Summary

Official Symbol
inx-3
Official Full Name
Innexin-3
Primary source
WormBase:WBGene00002125
Locus tag
CELE_F22F4.2
See related
AllianceGenome:WB:WBGene00002125
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Enables actin filament binding activity and gap junction channel activity. Involved in embryonic morphogenesis and positive regulation of nematode pharyngeal pumping. Located in cytoplasm and gap junction. Is expressed in several structures, including interfacial epithelial cell; muscle cell; neurons; pharynx; and rectum. [provided by Alliance of Genome Resources, Oct 2024]
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Genomic context

See inx-3 in Genome Data Viewer
Location:
chromosome: X
Exon count:
3
Sequence:
Chromosome: X; NC_003284.9 (5996156..5998243)

Chromosome X - NC_003284.9Genomic Context describing neighboring genes Neighboring gene Kinesin-like protein Neighboring gene DUF4265 domain-containing protein Neighboring gene ncRNA Neighboring gene CC domain-containing protein Neighboring gene Uncharacterized protein Neighboring gene ncRNA Neighboring gene SUppressor of Pkc-3 (pkc-3) Sterility

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
enables actin filament binding IDA
Inferred from Direct Assay
more info
PubMed 
enables gap junction channel activity IBA
Inferred from Biological aspect of Ancestor
more info
 
enables gap junction channel activity IMP
Inferred from Mutant Phenotype
more info
PubMed 
enables gap junction channel activity ISS
Inferred from Sequence or Structural Similarity
more info
 
enables gap junction hemi-channel activity ISS
Inferred from Sequence or Structural Similarity
more info
 
Process Evidence Code Pubs
involved_in embryonic morphogenesis IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in monoatomic ion transmembrane transport IEA
Inferred from Electronic Annotation
more info
 
involved_in positive regulation of nematode pharyngeal pumping IMP
Inferred from Mutant Phenotype
more info
PubMed 
Component Evidence Code Pubs
located_in cytoplasm IDA
Inferred from Direct Assay
more info
PubMed 
is_active_in gap junction IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in gap junction IDA
Inferred from Direct Assay
more info
PubMed 
located_in gap junction IEA
Inferred from Electronic Annotation
more info
 
is_active_in plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
Innexin-3
NP_509002.2
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003284.9 Reference assembly

    Range
    5996156..5998243
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_076601.7NP_509002.2  Innexin-3 [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_509002.2

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q17393, Q19746
    Conserved Domains (1) summary
    pfam00876
    Location:21370
    Innexin; Innexin