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spc-1 SPeCtrin [ Caenorhabditis elegans ]

Gene ID: 180603, updated on 5-Sep-2019

Summary

Gene symbol
spc-1
Gene description
SPeCtrin
Primary source
WormBase:WBGene00004951
Locus tag
CELE_K10B3.10
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis

Genomic context

See spc-1 in Genome Data Viewer
Location:
chromosome: X
Exon count:
14
Sequence:
Chromosome: X; NC_003284.9 (3117439..3127073, complement)

Chromosome X - NC_003284.9Genomic Context describing neighboring genes Neighboring gene Glyceraldehyde-3-phosphate dehydrogenase 3 Neighboring gene Glyceraldehyde-3-phosphate dehydrogenase 2 Neighboring gene ATPase inhibitor mai-1, mitochondrial Neighboring gene hypothetical protein Neighboring gene hypothetical protein

Pathways from BioSystems

General gene information

Markers

Homology

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
calcium ion binding IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
embryonic body morphogenesis IMP
Inferred from Mutant Phenotype
more info
PubMed 
nematode larval development IMP
Inferred from Mutant Phenotype
more info
PubMed 
positive regulation of multicellular organism growth IMP
Inferred from Mutant Phenotype
more info
PubMed 
regulation of locomotion IMP
Inferred from Mutant Phenotype
more info
PubMed 

General protein information

Preferred Names
SPeCtrin
NP_001256999.1
  • Product from WormBase gene class spc;
    Confirmed by transcript evidence
NP_001257000.1
  • Product from WormBase gene class spc;
    Partially confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003284.9 Reference assembly

    Range
    3117439..3127073 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001270070.2NP_001256999.1  SPeCtrin [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_001256999.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    G4S034
    Conserved Domains (6) summary
    smart00150
    Location:14071504
    SPEC; Spectrin repeats
    cd11808
    Location:9871039
    SH3_Alpha_Spectrin; Src homology 3 domain of Alpha Spectrin
    COG5126
    Location:22642421
    FRQ1; Ca2+-binding protein, EF-hand superfamily [Signal transduction mechanisms]
    cd00051
    Location:22812349
    EFh; EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to ...
    cd00176
    Location:62272
    SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
    pfam08726
    Location:23562426
    EFhand_Ca_insen; Ca2+ insensitive EF hand
  2. NM_001270071.2NP_001257000.1  SPeCtrin [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_001257000.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q21408
    Conserved Domains (7) summary
    smart00150
    Location:14121509
    SPEC; Spectrin repeats
    cd11808
    Location:9871039
    SH3_Alpha_Spectrin; Src homology 3 domain of Alpha Spectrin
    COG5126
    Location:22692426
    FRQ1; Ca2+-binding protein, EF-hand superfamily [Signal transduction mechanisms]
    cd00051
    Location:22862354
    EFh; EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to ...
    cd00176
    Location:62272
    SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
    pfam00435
    Location:907973
    Spectrin; Spectrin repeat
    pfam08726
    Location:23612431
    EFhand_Ca_insen; Ca2+ insensitive EF hand
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