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pdk-1 3-phosphoinositide-dependent protein kinase 1 [ Caenorhabditis elegans ]

Gene ID: 180475, updated on 19-Aug-2018

Summary

Gene symbol
pdk-1
Gene description
3-phosphoinositide-dependent protein kinase 1
Primary source
WormBase:WBGene00003965
Locus tag
CELE_H42K12.1
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis

Genomic context

See pdk-1 in Genome Data Viewer
Location:
chromosome: X
Exon count:
11
Sequence:
Chromosome: X; NC_003284.9 (1321363..1327493)

Chromosome X - NC_003284.9Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene hypothetical protein Neighboring gene hypothetical protein Neighboring gene TransThyretin-Related family domain

Pathways from BioSystems

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
ATP binding IEA
Inferred from Electronic Annotation
more info
 
kinase activity IEA
Inferred from Electronic Annotation
more info
 
nucleotide binding IEA
Inferred from Electronic Annotation
more info
 
protein kinase activity IEA
Inferred from Electronic Annotation
more info
 
protein kinase activity IMP
Inferred from Mutant Phenotype
more info
PubMed 
protein serine/threonine kinase activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
protein serine/threonine kinase activity IEA
Inferred from Electronic Annotation
more info
 
transferase activity IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
dauer larval development IGI
Inferred from Genetic Interaction
more info
PubMed 
dauer larval development IMP
Inferred from Mutant Phenotype
more info
PubMed 
intracellular signal transduction IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
learning or memory IMP
Inferred from Mutant Phenotype
more info
PubMed 
multicellular organism development IEA
Inferred from Electronic Annotation
more info
 
peptidyl-serine phosphorylation IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
phosphorylation IEA
Inferred from Electronic Annotation
more info
 
protein phosphorylation IEA
Inferred from Electronic Annotation
more info
 
protein phosphorylation IMP
Inferred from Mutant Phenotype
more info
PubMed 
regulation of chemotaxis IMP
Inferred from Mutant Phenotype
more info
PubMed 
regulation of synaptic growth at neuromuscular junction IGI
Inferred from Genetic Interaction
more info
PubMed 
Component Evidence Code Pubs
axon IDA
Inferred from Direct Assay
more info
PubMed 
cytoplasm IEA
Inferred from Electronic Annotation
more info
 
neuronal cell body IDA
Inferred from Direct Assay
more info
PubMed 
nucleus IDA
Inferred from Direct Assay
more info
PubMed 

General protein information

Preferred Names
3-phosphoinositide-dependent protein kinase 1
NP_001024742.1
  • Confirmed by transcript evidence
NP_001024743.1
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003284.9 Reference assembly

    Range
    1321363..1327493
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001029572.2NP_001024743.1  3-phosphoinositide-dependent protein kinase 1 [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_001024743.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q9Y1J3
    Conserved Domains (3) summary
    smart00220
    Location:69364
    S_TKc; Serine/Threonine protein kinases, catalytic domain
    cd01262
    Location:464570
    PH_PDK1; 3-Phosphoinositide dependent protein kinase 1 (PDK1) pleckstrin homology (PH) domain
    cd05581
    Location:67364
    STKc_PDK1; Catalytic domain of the Serine/Threonine Kinase, Phosphoinositide-dependent kinase 1
  2. NM_001029571.2NP_001024742.1  3-phosphoinositide-dependent protein kinase 1 [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_001024742.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q9Y1J3
    Conserved Domains (3) summary
    smart00220
    Location:69362
    S_TKc; Serine/Threonine protein kinases, catalytic domain
    cd01262
    Location:460566
    PH_PDK1; 3-Phosphoinositide dependent protein kinase 1 (PDK1) pleckstrin homology (PH) domain
    cd05581
    Location:67362
    STKc_PDK1; Catalytic domain of the Serine/Threonine Kinase, Phosphoinositide-dependent kinase 1
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