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pha-4 Defective pharyngeal development protein 4 [ Caenorhabditis elegans ]

Gene ID: 180357, updated on 19-Oct-2019

Summary

Gene symbol
pha-4
Gene description
Defective pharyngeal development protein 4
Primary source
WormBase:WBGene00004013
Locus tag
CELE_F38A6.1
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis

Genomic context

See pha-4 in Genome Data Viewer
Location:
chromosome: V
Exon count:
8
Sequence:
Chromosome: V; NC_003283.11 (20753052..20760309)

Chromosome V - NC_003283.11Genomic Context describing neighboring genes Neighboring gene J domain-containing protein Neighboring gene Serpentine Receptor, class XA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene Echinoderm microtubule-associated protein-like elp-1

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Pathways from BioSystems

  • Longevity regulating pathway - multiple species, organism-specific biosystem (from KEGG)
    Longevity regulating pathway - multiple species, organism-specific biosystemAging is a complex process of accumulation of molecular, cellular, and organ damage, leading to loss of function and increased vulnerability to disease and death. Despite the complexity of aging, rec...
  • Longevity regulating pathway - multiple species, conserved biosystem (from KEGG)
    Longevity regulating pathway - multiple species, conserved biosystemAging is a complex process of accumulation of molecular, cellular, and organ damage, leading to loss of function and increased vulnerability to disease and death. Despite the complexity of aging, rec...
  • Longevity regulating pathway - worm, organism-specific biosystem (from KEGG)
    Longevity regulating pathway - worm, organism-specific biosystemThe nematode Caenorhabditis elegans has proven to be a very useful tool for studying the genetics of longevity due to its simple biology. Over 70 genes have been found to influence lifespan in this w...
  • Longevity regulating pathway - worm, conserved biosystem (from KEGG)
    Longevity regulating pathway - worm, conserved biosystemThe nematode Caenorhabditis elegans has proven to be a very useful tool for studying the genetics of longevity due to its simple biology. Over 70 genes have been found to influence lifespan in this w...

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
DNA binding IEA
Inferred from Electronic Annotation
more info
 
DNA-binding transcription factor activity IEA
Inferred from Electronic Annotation
more info
 
DNA-binding transcription factor activity, RNA polymerase II-specific IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
DNA-binding transcription factor activity, RNA polymerase II-specific IMP
Inferred from Mutant Phenotype
more info
PubMed 
sequence-specific DNA binding IDA
Inferred from Direct Assay
more info
PubMed 
sequence-specific DNA binding IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
anatomical structure morphogenesis IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
cell differentiation IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
cell differentiation IMP
Inferred from Mutant Phenotype
more info
PubMed 
cell fate specification involved in pattern specification IMP
Inferred from Mutant Phenotype
more info
PubMed 
determination of adult lifespan IGI
Inferred from Genetic Interaction
more info
PubMed 
embryonic morphogenesis IMP
Inferred from Mutant Phenotype
more info
PubMed 
multicellular organism development IEA
Inferred from Electronic Annotation
more info
 
pharynx development IGI
Inferred from Genetic Interaction
more info
PubMed 
pharynx development IMP
Inferred from Mutant Phenotype
more info
PubMed 
positive regulation of macroautophagy IMP
Inferred from Mutant Phenotype
more info
PubMed 
positive regulation of transcription by RNA polymerase II IMP
Inferred from Mutant Phenotype
more info
PubMed 
positive regulation of translation IMP
Inferred from Mutant Phenotype
more info
PubMed 
regulation of transcription by RNA polymerase II IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
regulation of transcription, DNA-templated IEA
Inferred from Electronic Annotation
more info
 
response to caloric restriction IDA
Inferred from Direct Assay
more info
PubMed 
response to sodium arsenite IMP
Inferred from Mutant Phenotype
more info
PubMed 
Component Evidence Code Pubs
nucleus IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
nucleus IDA
Inferred from Direct Assay
more info
PubMed 
nucleus IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
Defective pharyngeal development protein 4
NP_001041114.1
  • Confirmed by transcript evidence
NP_001041115.1
  • Confirmed by transcript evidence
NP_001041116.1
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003283.11 Reference assembly

    Range
    20753052..20760309
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001047649.3NP_001041114.1  Defective pharyngeal development protein 4 [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_001041114.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q17381
    Conserved Domains (1) summary
    smart00339
    Location:236324
    FH; FORKHEAD
  2. NM_001047650.3NP_001041115.1  Defective pharyngeal development protein 4 [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_001041115.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q17381
    Conserved Domains (1) summary
    smart00339
    Location:172260
    FH; FORKHEAD
  3. NM_001047651.4NP_001041116.1  Defective pharyngeal development protein 4 [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_001041116.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q17381
    Conserved Domains (1) summary
    smart00339
    Location:141229
    FH; FORKHEAD
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