U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

C01G10.7 HpcH/HpaI aldolase/citrate lyase domain-containing protein [ Caenorhabditis elegans ]

Gene ID: 180018, updated on 4-Jan-2025

Summary

Go to the top of the page Help
Official Symbol
C01G10.7
Official Full Name
HpcH/HpaI aldolase/citrate lyase domain-containing protein
Primary source
WormBase:WBGene00007234
Locus tag
CELE_C01G10.7
See related
AllianceGenome:WB:WBGene00007234
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to enable magnesium ion binding activity. Predicted to be involved in oxaloacetate metabolic process. Is expressed in several structures, including head; head mesodermal cell; intestine; pharynx; and rectal gland cell. Orthologous to human CLYBL (citramalyl-CoA lyase). [provided by Alliance of Genome Resources, Jan 2025]
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
See C01G10.7 in Genome Data Viewer
Location:
chromosome: V
Exon count:
3
Sequence:
Chromosome: V; NC_003283.11 (15085747..15086918)

Chromosome V - NC_003283.11Genomic Context describing neighboring genes Neighboring gene MitMem_reg domain-containing protein;UNC-76 Neighboring gene putative tRNA N6-adenosine threonylcarbamoyltransferase, mitochondrial Neighboring gene Methylthioribose-1-phosphate isomerase Neighboring gene Activator of Hsp90 ATPase AHSA1-like N-terminal domain-containing protein Neighboring gene FIP (Fungus-Induced Protein) Related Neighboring gene FIP (Fungus-Induced Protein) Related Neighboring gene FIP (Fungus-Induced Protein) Related Neighboring gene FIP (Fungus-Induced Protein) Related

Genomic regions, transcripts, and products

Go to the top of the page Help
Genomic Sequence:
NC_003283.11

Go to nucleotide: Graphics FASTA GenBank

Bibliography

Go to the top of the pageHelp

Related articles in PubMed

  1. EPIC: software toolkit for elution profile-based inference of protein complexes. Hu LZ, et al. Nat Methods, 2019 Aug. PMID 31308550, Free PMC Article
  2. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

GeneRIFs: Gene References Into Functions

Interactions

Go to the top of the page Help
Products Interactant Other Gene Complex Source Pubs Description

General gene information

Go to the top of the page Help

Markers

Homology

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
enables catalytic activity IEA
Inferred from Electronic Annotation
more info
  
enables lyase activity IEA
Inferred from Electronic Annotation
more info
  
enables magnesium ion binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in oxaloacetate metabolic process IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

Go to the top of the page Help
Preferred Names
HpcH/HpaI aldolase/citrate lyase domain-containing protein
NP_506716.1
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003283.11 Reference assembly

    Range
    15085747..15086918
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_074315.9 → NP_506716.1  HpcH/HpaI aldolase/citrate lyase domain-containing protein [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_506716.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q93167
    Conserved Domains (2) summary
    pfam03328
    Location:26 → 259
    HpcH_HpaI; HpcH/HpaI aldolase/citrate lyase family
    cl21481
    Location:230 → 303
    malate_synt; Malate synthase catalyzes the Claisen condensation of glyoxylate and acetyl-CoA to malyl-CoA , which hydrolyzes to malate and CoA. This reaction is part of the glyoxylate cycle, which allows certain organisms, like plants and fungi, to derive their ...
Nucleotide Protein
Heading Accession and Version

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

Molecular Biology Databases
Research Materials
Tools