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uig-1 UNC-112-Interacting Guanine nucleotide exchange factor [ Caenorhabditis elegans ]

Gene ID: 179808, updated on 12-May-2019

Summary

Gene symbol
uig-1
Gene description
UNC-112-Interacting Guanine nucleotide exchange factor
Primary source
WormBase:WBGene00009337
Locus tag
CELE_F32F2.1
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis

Genomic context

See uig-1 in Genome Data Viewer
Location:
chromosome: V
Exon count:
18
Sequence:
Chromosome: V; NC_003283.11 (13273590..13295826, complement)

Chromosome V - NC_003283.11Genomic Context describing neighboring genes Neighboring gene hypothetical protein Neighboring gene bZIP transcription factor family Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene hypothetical protein Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene hypothetical protein Neighboring gene C. Elegans Homeobox

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
Rho guanyl-nucleotide exchange factor activity IEA
Inferred from Electronic Annotation
more info
 
guanyl-nucleotide exchange factor activity IEA
Inferred from Electronic Annotation
more info
 
protein domain specific binding IPI
Inferred from Physical Interaction
more info
PubMed 
Process Evidence Code Pubs
regulation of Rho protein signal transduction IEA
Inferred from Electronic Annotation
more info
 
regulation of engulfment of apoptotic cell IMP
Inferred from Mutant Phenotype
more info
PubMed 
Component Evidence Code Pubs
striated muscle dense body IDA
Inferred from Direct Assay
more info
PubMed 

General protein information

Preferred Names
UNC-112-Interacting Guanine nucleotide exchange factor
NP_001256488.1
  • Product from WormBase gene class uig;
    Partially confirmed by transcript evidence
NP_001256489.1
  • Partially confirmed by transcript evidence;
    Product from WormBase gene class uig
NP_001256490.1
  • Partially confirmed by transcript evidence;
    Product from WormBase gene class uig
NP_001256491.1
  • Product from WormBase gene class uig;
    Confirmed by transcript evidence
NP_001256492.1
  • Product from WormBase gene class uig;
    Partially confirmed by transcript evidence
NP_001256493.1
  • Product from WormBase gene class uig;
    Partially confirmed by transcript evidence
NP_001256494.1
  • Product from WormBase gene class uig;
    Partially confirmed by transcript evidence
NP_001256495.1
  • Product from WormBase gene class uig;
    Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003283.11 Reference assembly

    Range
    13273590..13295826 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001269561.1NP_001256490.1  UNC-112-Interacting Guanine nucleotide exchange factor [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_001256490.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    G5EER5
    Conserved Domains (2) summary
    cd13243
    Location:419570
    PH_PLEKHG1_G2_G3; Pleckstrin homology domain-containing family G members 1, 2, and 3 pleckstrin homology (PH) domain
    pfam00621
    Location:260438
    RhoGEF; RhoGEF domain
  2. NM_001269560.1NP_001256489.1  UNC-112-Interacting Guanine nucleotide exchange factor [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_001256489.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    G5EF62
    Conserved Domains (2) summary
    cd13243
    Location:439590
    PH_PLEKHG1_G2_G3; Pleckstrin homology domain-containing family G members 1, 2, and 3 pleckstrin homology (PH) domain
    pfam00621
    Location:280458
    RhoGEF; RhoGEF domain
  3. NM_001269559.1NP_001256488.1  UNC-112-Interacting Guanine nucleotide exchange factor [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_001256488.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    B6GUP8
    Conserved Domains (2) summary
    cd13243
    Location:425576
    PH_PLEKHG1_G2_G3; Pleckstrin homology domain-containing family G members 1, 2, and 3 pleckstrin homology (PH) domain
    pfam00621
    Location:266444
    RhoGEF; RhoGEF domain
  4. NM_001269562.1NP_001256491.1  UNC-112-Interacting Guanine nucleotide exchange factor [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_001256491.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q9XXM9
    Conserved Domains (2) summary
    cd13243
    Location:386537
    PH_PLEKHG1_G2_G3; Pleckstrin homology domain-containing family G members 1, 2, and 3 pleckstrin homology (PH) domain
    pfam00621
    Location:227405
    RhoGEF; RhoGEF domain
  5. NM_001269563.1NP_001256492.1  UNC-112-Interacting Guanine nucleotide exchange factor [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_001256492.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    D4YWB8
    Conserved Domains (2) summary
    cd13243
    Location:242393
    PH_PLEKHG1_G2_G3; Pleckstrin homology domain-containing family G members 1, 2, and 3 pleckstrin homology (PH) domain
    pfam00621
    Location:83261
    RhoGEF; RhoGEF domain
  6. NM_001269564.1NP_001256493.1  UNC-112-Interacting Guanine nucleotide exchange factor [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_001256493.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    H1UBJ0
    Conserved Domains (1) summary
    cl17171
    Location:173
    PH-like; Pleckstrin homology-like domain
  7. NM_001269565.1NP_001256494.1  UNC-112-Interacting Guanine nucleotide exchange factor [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_001256494.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    D4YWB9
  8. NM_001269566.1NP_001256495.1  UNC-112-Interacting Guanine nucleotide exchange factor [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_001256495.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    D4YWC0
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