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eat-6 Sodium/potassium-transporting ATPase subunit alpha [ Caenorhabditis elegans ]

Gene ID: 179796, updated on 22-Aug-2021

Summary

Gene symbol
eat-6
Gene description
Sodium/potassium-transporting ATPase subunit alpha
Primary source
WormBase:WBGene00001137
Locus tag
CELE_B0365.3
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
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Genomic context

See eat-6 in Genome Data Viewer
Location:
chromosome: V
Exon count:
5
Sequence:
Chromosome: V; NC_003283.11 (13126414..13129995, complement)

Chromosome V - NC_003283.11Genomic Context describing neighboring genes Neighboring gene ATP-citrate synthase Neighboring gene pseudo Neighboring gene ncRNA Neighboring gene CPG4 domain-containing protein

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 
enables ATP binding ISS
Inferred from Sequence or Structural Similarity
more info
PubMed 
enables ATP hydrolysis activity IEA
Inferred from Electronic Annotation
more info
 
enables P-type potassium transmembrane transporter activity IEA
Inferred from Electronic Annotation
more info
 
enables P-type sodium:potassium-exchanging transporter activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables P-type sodium:potassium-exchanging transporter activity IMP
Inferred from Mutant Phenotype
more info
PubMed 
enables P-type sodium:potassium-exchanging transporter activity ISS
Inferred from Sequence or Structural Similarity
more info
PubMed 
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
 
enables nucleotide binding IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
involved_in action potential IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in cellular potassium ion homeostasis IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in cellular sodium ion homeostasis IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in establishment or maintenance of transmembrane electrochemical gradient IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in ion transport IEA
Inferred from Electronic Annotation
more info
 
involved_in potassium ion import across plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in potassium ion transport IEA
Inferred from Electronic Annotation
more info
 
involved_in potassium ion transport IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in potassium ion transport ISS
Inferred from Sequence or Structural Similarity
more info
PubMed 
involved_in proton transmembrane transport IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in regulation of membrane potential IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in regulation of muscle contraction IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in reproduction IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in sodium ion export across plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in sodium ion transport IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in sodium ion transport ISS
Inferred from Sequence or Structural Similarity
more info
PubMed 
Component Evidence Code Pubs
located_in integral component of membrane IEA
Inferred from Electronic Annotation
more info
 
located_in membrane IDA
Inferred from Direct Assay
more info
PubMed 
located_in membrane IEA
Inferred from Electronic Annotation
more info
 
located_in plasma membrane ISS
Inferred from Sequence or Structural Similarity
more info
PubMed 

General protein information

Preferred Names
Sodium/potassium-transporting ATPase subunit alpha
NP_506269.1
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003283.11 Reference assembly

    Range
    13126414..13129995 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_073868.6NP_506269.1  Sodium/potassium-transporting ATPase subunit alpha [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_506269.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    P90735
    Conserved Domains (6) summary
    smart00831
    Location:1892
    Cation_ATPase_N; Cation transporter/ATPase, N-terminus
    COG4087
    Location:644725
    COG4087; Soluble P-type ATPase [General function prediction only]
    TIGR01106
    Location:6996
    ATPase-IIC_X-K; sodium or proton efflux -- potassium uptake antiporter, P-type ATPase, alpha subunit
    pfam00122
    Location:112343
    E1-E2_ATPase; E1-E2 ATPase
    pfam00689
    Location:772981
    Cation_ATPase_C; Cation transporting ATPase, C-terminus
    pfam13246
    Location:404494
    Cation_ATPase; Cation transport ATPase (P-type)
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