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elpc-3 Probable elongator complex protein 3 [ Caenorhabditis elegans ]

Gene ID: 179669, updated on 19-Aug-2018

Summary

Gene symbol
elpc-3
Gene description
Probable elongator complex protein 3
Primary source
WormBase:WBGene00014123
Locus tag
CELE_ZK863.3
Gene type
protein coding
RNA name
Probable elongator complex protein 3
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis

Genomic context

See elpc-3 in Genome Data Viewer
Location:
chromosome: V
Exon count:
5
Sequence:
Chromosome: V; NC_003283.11 (12179584..12181410, complement)

Chromosome V - NC_003283.11Genomic Context describing neighboring genes Neighboring gene hypothetical protein Neighboring gene ncRNA Neighboring gene C-type LECtin Neighboring gene U Six snRNA Interacting Protein Neighboring gene Serpentine Receptor, class D (delta)

Pathways from BioSystems

General gene information

Markers

Homology

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
catalytic activity IEA
Inferred from Electronic Annotation
more info
 
histone acetyltransferase activity IEA
Inferred from Electronic Annotation
more info
 
iron-sulfur cluster binding IEA
Inferred from Electronic Annotation
more info
 
metal ion binding IEA
Inferred from Electronic Annotation
more info
 
phosphorylase kinase regulator activity ISS
Inferred from Sequence or Structural Similarity
more info
 
transferase activity IEA
Inferred from Electronic Annotation
more info
 
transferase activity, transferring acyl groups IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
embryonic morphogenesis IGI
Inferred from Genetic Interaction
more info
PubMed 
histone acetylation IEA
Inferred from Electronic Annotation
more info
 
olfactory learning IMP
Inferred from Mutant Phenotype
more info
PubMed 
oocyte development IGI
Inferred from Genetic Interaction
more info
PubMed 
regulation of protein kinase activity IEA
Inferred from Electronic Annotation
more info
 
regulation of transcription by RNA polymerase II ISS
Inferred from Sequence or Structural Similarity
more info
 
regulation of transcription, DNA-templated IEA
Inferred from Electronic Annotation
more info
 
spermatogenesis IGI
Inferred from Genetic Interaction
more info
PubMed 
tRNA wobble base 5-methoxycarbonylmethyl-2-thiouridinylation IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
tRNA wobble uridine modification IMP
Inferred from Mutant Phenotype
more info
PubMed 
transcription, DNA-templated IEA
Inferred from Electronic Annotation
more info
 
translation IMP
Inferred from Mutant Phenotype
more info
PubMed 
vulval development IGI
Inferred from Genetic Interaction
more info
PubMed 
Component Evidence Code Pubs
Elongator holoenzyme complex IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
cytoplasm ISS
Inferred from Sequence or Structural Similarity
more info
 
nucleus IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
nucleus IEA
Inferred from Electronic Annotation
more info
 
transcription elongation factor complex ISS
Inferred from Sequence or Structural Similarity
more info
 

General protein information

Preferred Names
Probable elongator complex protein 3
NP_506055.2
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003283.11 Reference assembly

    Range
    12179584..12181410 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_073654.4NP_506055.2  Probable elongator complex protein 3 [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_506055.2

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q23651
    Conserved Domains (3) summary
    cd01335
    Location:92338
    Radical_SAM; Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster. ...
    TIGR01211
    Location:17542
    ELP3; radical SAM enzyme/protein acetyltransferase, ELP3 family
    pfam16199
    Location:310389
    Radical_SAM_C; Radical_SAM C-terminal domain
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