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pyc-1 Pyruvate carboxylase 1 [ Caenorhabditis elegans ]

Gene ID: 179616, updated on 10-Aug-2021

Summary

Gene symbol
pyc-1
Gene description
Pyruvate carboxylase 1
Primary source
WormBase:WBGene00004258
Locus tag
CELE_D2023.2
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
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Genomic context

See pyc-1 in Genome Data Viewer
Location:
chromosome: V
Exon count:
9
Sequence:
Chromosome: V; NC_003283.11 (11817783..11822365, complement)

Chromosome V - NC_003283.11Genomic Context describing neighboring genes Neighboring gene C2 domain-containing protein Neighboring gene ncRNA Neighboring gene pseudo Neighboring gene Thialysine N-epsilon-acetyltransferase Neighboring gene Putative thiosulfate sulfurtransferase mpst-1

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

  • Homologs of the pyc-1 gene: The pyc-1 gene is conserved in human, chimpanzee, Rhesus monkey, dog, cow, mouse, rat, zebrafish, fruit fly, mosquito, S.cerevisiae, K.lactis, E.gossypii, S.pombe, M.oryzae, N.crassa, and frog.
  • Orthologs

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 
enables biotin binding IEA
Inferred from Electronic Annotation
more info
 
enables catalytic activity IEA
Inferred from Electronic Annotation
more info
 
enables ligase activity IEA
Inferred from Electronic Annotation
more info
 
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
 
enables nucleotide binding IEA
Inferred from Electronic Annotation
more info
 
enables pyruvate carboxylase activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables pyruvate carboxylase activity IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
involved_in gluconeogenesis IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in gluconeogenesis IEA
Inferred from Electronic Annotation
more info
 
involved_in metabolic process IEA
Inferred from Electronic Annotation
more info
 
involved_in pyruvate metabolic process IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in pyruvate metabolic process IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 
located_in mitochondrion HDA PubMed 

General protein information

Preferred Names
Pyruvate carboxylase 1
NP_001368099.1
  • Confirmed by transcript evidence
NP_001369995.1
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003283.11 Reference assembly

    Range
    11817783..11822365 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001383412.2NP_001369995.1  Pyruvate carboxylase 1 [Caenorhabditis elegans]

    Status: REVIEWED

    Conserved Domains (1) summary
    PRK12999
    Location:281175
    PRK12999; pyruvate carboxylase; Reviewed
  2. NM_001380776.1NP_001368099.1  Pyruvate carboxylase 1 [Caenorhabditis elegans]

    Status: REVIEWED

    Conserved Domains (1) summary
    cl39082
    Location:2616
    PycA; Pyruvate carboxylase [Energy production and conversion]
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