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Naga N-acetyl galactosaminidase, alpha [ Mus musculus (house mouse) ]

Gene ID: 17939, updated on 31-Jan-2019

Summary

Official Symbol
Nagaprovided by MGI
Official Full Name
N-acetyl galactosaminidase, alphaprovided by MGI
Primary source
MGI:MGI:1261422
See related
Ensembl:ENSMUSG00000022453
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Expression
Ubiquitous expression in colon adult (RPKM 76.1), kidney adult (RPKM 46.4) and 28 other tissues See more
Orthologs

Genomic context

See Naga in Genome Data Viewer
Location:
15 E1; 15 38.56 cM
Exon count:
10
Annotation release Status Assembly Chr Location
106 current GRCm38.p4 (GCF_000001635.24) 15 NC_000081.6 (82329532..82338852, complement)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 15 NC_000081.5 (82159962..82169256, complement)

Chromosome 15 - NC_000081.6Genomic Context describing neighboring genes Neighboring gene septin 3 Neighboring gene WBP2 N-terminal like Neighboring gene PH domain containing endocytic trafficking adaptor 2 Neighboring gene single-pass membrane protein with aspartate rich tail 1

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Targeted (1) 

Pathways from BioSystems

  • Glycosphingolipid biosynthesis - globo and isoglobo series, organism-specific biosystem (from KEGG)
    Glycosphingolipid biosynthesis - globo and isoglobo series, organism-specific biosystem
    Glycosphingolipid biosynthesis - globo and isoglobo series
  • Lysosome, organism-specific biosystem (from KEGG)
    Lysosome, organism-specific biosystemLysosomes are membrane-delimited organelles in animal cells serving as the cell's main digestive compartment to which all sorts of macromolecules are delivered for degradation. They contain more than...
  • Lysosome, conserved biosystem (from KEGG)
    Lysosome, conserved biosystemLysosomes are membrane-delimited organelles in animal cells serving as the cell's main digestive compartment to which all sorts of macromolecules are delivered for degradation. They contain more than...

General gene information

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
alpha-N-acetylgalactosaminidase activity ISO
Inferred from Sequence Orthology
more info
 
alpha-galactosidase activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
catalytic activity IEA
Inferred from Electronic Annotation
more info
 
hydrolase activity IEA
Inferred from Electronic Annotation
more info
 
hydrolase activity, acting on glycosyl bonds IEA
Inferred from Electronic Annotation
more info
 
hydrolase activity, hydrolyzing O-glycosyl compounds IEA
Inferred from Electronic Annotation
more info
 
protein homodimerization activity ISO
Inferred from Sequence Orthology
more info
 
Process Evidence Code Pubs
carbohydrate catabolic process ISO
Inferred from Sequence Orthology
more info
 
carbohydrate metabolic process IEA
Inferred from Electronic Annotation
more info
 
glycolipid catabolic process ISO
Inferred from Sequence Orthology
more info
 
glycoside catabolic process IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
glycosylceramide catabolic process IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
metabolic process IEA
Inferred from Electronic Annotation
more info
 
oligosaccharide metabolic process IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Component Evidence Code Pubs
cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
lysosome IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
alpha-N-acetylgalactosaminidase
Names
alpha-galactosidase B
NP_032695.3
XP_006520624.1
XP_006520625.1
XP_006520626.1

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001355546.1NP_001342475.1  alpha-N-acetylgalactosaminidase

    Status: VALIDATED

    Source sequence(s)
    AC104325
    Conserved Domains (1) summary
    cl07893
    Location:1273
    AmyAc_family; Alpha amylase catalytic domain family
  2. NM_008669.4NP_032695.3  alpha-N-acetylgalactosaminidase isoform 1 precursor

    See identical proteins and their annotated locations for NP_032695.3

    Status: VALIDATED

    Source sequence(s)
    AK077116, AK153002, CJ093426
    Consensus CDS
    CCDS27686.1
    UniProtKB/Swiss-Prot
    Q9QWR8
    UniProtKB/TrEMBL
    Q3U6T2
    Related
    ENSMUSP00000023088.7, ENSMUST00000023088.7
    Conserved Domains (1) summary
    cl07893
    Location:25394
    AmyAc_family; Alpha amylase catalytic domain family

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm38.p4 C57BL/6J

Genomic

  1. NC_000081.6 Reference GRCm38.p4 C57BL/6J

    Range
    82329532..82338852 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006520562.3XP_006520625.1  alpha-N-acetylgalactosaminidase isoform X2

    Conserved Domains (1) summary
    cl07893
    Location:1273
    AmyAc_family; Alpha amylase catalytic domain family
  2. XM_006520561.3XP_006520624.1  alpha-N-acetylgalactosaminidase isoform X1

    Conserved Domains (1) summary
    cl07893
    Location:9378
    AmyAc_family; Alpha amylase catalytic domain family
  3. XM_006520563.3XP_006520626.1  alpha-N-acetylgalactosaminidase isoform X3

    Conserved Domains (1) summary
    cl07893
    Location:11207
    AmyAc_family; Alpha amylase catalytic domain family
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