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rpm-1 E3 ubiquitin-protein ligase rpm-1 [ Caenorhabditis elegans ]

Gene ID: 179259, updated on 5-Sep-2019

Summary

Gene symbol
rpm-1
Gene description
E3 ubiquitin-protein ligase rpm-1
Primary source
WormBase:WBGene00004457
Locus tag
CELE_C01B7.6
Gene type
protein coding
RNA name
E3 ubiquitin-protein ligase rpm-1
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis

Genomic context

See rpm-1 in Genome Data Viewer
Location:
chromosome: V
Exon count:
15
Sequence:
Chromosome: V; NC_003283.11 (8805399..8819955, complement)

Chromosome V - NC_003283.11Genomic Context describing neighboring genes Neighboring gene MAGUK family Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene DUF19 domain-containing protein

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
metal ion binding IEA
Inferred from Electronic Annotation
more info
 
mitogen-activated protein kinase kinase kinase binding IPI
Inferred from Physical Interaction
more info
PubMed 
protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
protein phosphatase binding IPI
Inferred from Physical Interaction
more info
PubMed 
transferase activity IEA
Inferred from Electronic Annotation
more info
 
ubiquitin protein ligase activity IDA
Inferred from Direct Assay
more info
PubMed 
zinc ion binding IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
body morphogenesis IMP
Inferred from Mutant Phenotype
more info
PubMed 
dorsal/ventral axon guidance IGI
Inferred from Genetic Interaction
more info
PubMed 
locomotion IGI
Inferred from Genetic Interaction
more info
PubMed 
negative regulation of 3'-UTR-mediated mRNA stabilization IMP
Inferred from Mutant Phenotype
more info
PubMed 
negative regulation of MAPK cascade IGI
Inferred from Genetic Interaction
more info
PubMed 
negative regulation of MAPK cascade IMP
Inferred from Mutant Phenotype
more info
PubMed 
negative regulation of axon extension IMP
Inferred from Mutant Phenotype
more info
PubMed 
negative regulation of axon extension involved in axon guidance IGI
Inferred from Genetic Interaction
more info
PubMed 
negative regulation of axon extension involved in axon guidance IMP
Inferred from Mutant Phenotype
more info
PubMed 
negative regulation of axon extension involved in regeneration IMP
Inferred from Mutant Phenotype
more info
PubMed 
negative regulation of axon regeneration IMP
Inferred from Mutant Phenotype
more info
PubMed 
negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage IMP
Inferred from Mutant Phenotype
more info
PubMed 
negative regulation of sensory neuron axon guidance IGI
Inferred from Genetic Interaction
more info
PubMed 
negative regulation of sensory neuron axon guidance IMP
Inferred from Mutant Phenotype
more info
PubMed 
oviposition IMP
Inferred from Mutant Phenotype
more info
PubMed 
positive regulation of presynapse assembly IMP
Inferred from Mutant Phenotype
more info
PubMed 
positive regulation of synapse assembly IMP
Inferred from Mutant Phenotype
more info
PubMed 
protein ubiquitination IEA
Inferred from Electronic Annotation
more info
 
regulation of 3'-UTR-mediated mRNA stabilization IGI
Inferred from Genetic Interaction
more info
PubMed 
regulation of axon extension involved in axon guidance IGI
Inferred from Genetic Interaction
more info
PubMed 
regulation of dorsal/ventral axon guidance IGI
Inferred from Genetic Interaction
more info
PubMed 
regulation of motor neuron axon guidance IGI
Inferred from Genetic Interaction
more info
PubMed 
regulation of presynapse assembly IGI
Inferred from Genetic Interaction
more info
PubMed 
regulation of protein stability IMP
Inferred from Mutant Phenotype
more info
PubMed 
regulation of sensory neuron axon guidance IGI
Inferred from Genetic Interaction
more info
PubMed 
regulation of synapse organization IGI
Inferred from Genetic Interaction
more info
PubMed 
regulation of synapse organization IMP
Inferred from Mutant Phenotype
more info
PubMed 
regulation of synaptic growth at neuromuscular junction IGI
Inferred from Genetic Interaction
more info
PubMed 
regulation of synaptic growth at neuromuscular junction IMP
Inferred from Mutant Phenotype
more info
PubMed 
Component Evidence Code Pubs
axon IDA
Inferred from Direct Assay
more info
PubMed 
axon IEA
Inferred from Electronic Annotation
more info
 
cell projection IEA
Inferred from Electronic Annotation
more info
 
neuromuscular junction IDA
Inferred from Direct Assay
more info
PubMed 
nucleus IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
presynaptic periactive zone IDA
Inferred from Direct Assay
more info
PubMed 
synapse IDA
Inferred from Direct Assay
more info
PubMed 

General protein information

Preferred Names
E3 ubiquitin-protein ligase rpm-1
NP_505267.1
  • Partially confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003283.11 Reference assembly

    Range
    8805399..8819955 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_072866.4NP_505267.1  E3 ubiquitin-protein ligase rpm-1 [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_505267.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q17551
    Conserved Domains (6) summary
    smart00336
    Location:33313379
    BBOX; B-Box-type zinc finger
    pfam00415
    Location:787833
    RCC1; Regulator of chromosome condensation (RCC1) repeat
    pfam08005
    Location:10571203
    PHR; PHR domain
    pfam13540
    Location:769798
    RCC1_2; Regulator of chromosome condensation (RCC1) repeat
    pfam13639
    Location:35153567
    zf-RING_2; Ring finger domain
    cl02148
    Location:28913049
    APC10-like; APC10-like DOC1 domains in E3 ubiquitin ligases that mediate substrate ubiquitination
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