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F41E6.5 FMN hydroxy acid dehydrogenase domain-containing protein [ Caenorhabditis elegans ]

Gene ID: 179241, updated on 4-Jan-2025

Summary

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Official Symbol
F41E6.5
Official Full Name
FMN hydroxy acid dehydrogenase domain-containing protein
Primary source
WormBase:WBGene00018286
Locus tag
CELE_F41E6.5
See related
AllianceGenome:WB:WBGene00018286
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to enable (S)-2-hydroxy-acid oxidase activity. Predicted to be located in peroxisome. Predicted to be active in peroxisomal matrix. Is expressed in intestine and pharynx. Orthologous to several human genes including HAO1 (hydroxyacid oxidase 1). [provided by Alliance of Genome Resources, Jan 2025]
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Genomic context

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See F41E6.5 in Genome Data Viewer
Location:
chromosome: V
Exon count:
6
Sequence:
Chromosome: V; NC_003283.11 (8603480..8605181)

Chromosome V - NC_003283.11Genomic Context describing neighboring genes Neighboring gene Sushi domain-containing protein Neighboring gene Uncharacterized protein Neighboring gene Charged multivesicular body protein 5 Neighboring gene Serine/threonine-protein phosphatase 4 regulatory subunit 3-like central domain-containing protein Neighboring gene Fungus-Induced Protein Neighboring gene ncRNA

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003283.11

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
enables (S)-2-hydroxy-acid oxidase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables FMN binding IEA
Inferred from Electronic Annotation
more info
  
enables oxidoreductase activity IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
is_active_in peroxisomal matrix IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in peroxisome IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
FMN hydroxy acid dehydrogenase domain-containing protein
NP_001122941.1
  • Confirmed by transcript evidence
NP_001359850.1
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003283.11 Reference assembly

    Range
    8603480..8605181
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001129469.3 → NP_001122941.1  FMN hydroxy acid dehydrogenase domain-containing protein [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_001122941.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    B1GRK5
    Conserved Domains (1) summary
    pfam01070
    Location:18 → 361
    FMN_dh; FMN-dependent dehydrogenase

  2. NM_001373065.3 → NP_001359850.1  FMN hydroxy acid dehydrogenase domain-containing protein [Caenorhabditis elegans]

    Status: REVIEWED

    UniProtKB/TrEMBL
    O16457
    Conserved Domains (1) summary
    pfam01070
    Location:18 → 287
    FMN_dh; FMN-dependent dehydrogenase
Nucleotide Protein
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