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unc-68 hypothetical protein [ Caenorhabditis elegans ]

Gene ID: 179080, updated on 19-Oct-2019

Summary

Gene symbol
unc-68
Gene description
hypothetical protein
Primary source
WormBase:WBGene00006801
Locus tag
CELE_K11C4.5
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis

Genomic context

See unc-68 in Genome Data Viewer
Location:
chromosome: V
Exon count:
51
Sequence:
Chromosome: V; NC_003283.11 (6901683..6929038, complement)

Chromosome V - NC_003283.11Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene tRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA

Pathways from BioSystems

  • Calcium signaling pathway, organism-specific biosystem (from KEGG)
    Calcium signaling pathway, organism-specific biosystemCa2+ that enters the cell from the outside is a principal source of signal Ca2+. Entry of Ca2+ is driven by the presence of a large electrochemical gradient across the plasma membrane. Cells use this...
  • Calcium signaling pathway, conserved biosystem (from KEGG)
    Calcium signaling pathway, conserved biosystemCa2+ that enters the cell from the outside is a principal source of signal Ca2+. Entry of Ca2+ is driven by the presence of a large electrochemical gradient across the plasma membrane. Cells use this...

General gene information

Markers

Homology

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
calcium channel activity IEA
Inferred from Electronic Annotation
more info
 
calcium ion binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
calcium ion binding IEA
Inferred from Electronic Annotation
more info
 
calcium-induced calcium release activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
ion channel activity IEA
Inferred from Electronic Annotation
more info
 
protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
ryanodine-sensitive calcium-release channel activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
ryanodine-sensitive calcium-release channel activity IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
IRE1-mediated unfolded protein response HEP PubMed 
calcium ion transmembrane transport IEA
Inferred from Electronic Annotation
more info
 
calcium ion transport IEA
Inferred from Electronic Annotation
more info
 
cellular calcium ion homeostasis IEA
Inferred from Electronic Annotation
more info
 
ion transport IEA
Inferred from Electronic Annotation
more info
 
locomotion IMP
Inferred from Mutant Phenotype
more info
PubMed 
positive regulation of programmed cell death IGI
Inferred from Genetic Interaction
more info
PubMed 
protein localization to organelle IMP
Inferred from Mutant Phenotype
more info
PubMed 
release of sequestered calcium ion into cytosol IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
transmembrane transport IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
I band IDA
Inferred from Direct Assay
more info
PubMed 
Z disc IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
calcium channel complex IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
cytoplasmic vesicle membrane IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
integral component of membrane IEA
Inferred from Electronic Annotation
more info
 
membrane IEA
Inferred from Electronic Annotation
more info
 
plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
sarcolemma IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
sarcoplasmic reticulum IDA
Inferred from Direct Assay
more info
PubMed 
sarcoplasmic reticulum membrane IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
smooth endoplasmic reticulum IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 

General protein information

Preferred Names
hypothetical protein
NP_001343688.1
  • Confirmed by transcript evidence
NP_001343689.1
  • Confirmed by transcript evidence
NP_001343695.1
  • Confirmed by transcript evidence
NP_001343696.1
  • Confirmed by transcript evidence
NP_001343808.1
  • Partially confirmed by transcript evidence
NP_001343809.1
  • Partially confirmed by transcript evidence
NP_001343810.1
  • Partially confirmed by transcript evidence
NP_001343811.1
  • Partially confirmed by transcript evidence
NP_001343812.1
  • Partially confirmed by transcript evidence
NP_001343813.1
  • Partially confirmed by transcript evidence
NP_001343814.1
  • Partially confirmed by transcript evidence
NP_001343815.1
  • Partially confirmed by transcript evidence
NP_001343816.1
  • Partially confirmed by transcript evidence
NP_001343817.1
  • Partially confirmed by transcript evidence
NP_001343818.1
  • Partially confirmed by transcript evidence
NP_001343819.1
  • Partially confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003283.11 Reference assembly

    Range
    6901683..6929038 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001356673.2NP_001343696.1  Uncharacterized protein CELE_K11C4.5 [Caenorhabditis elegans]

    Status: REVIEWED

    Conserved Domains (11) summary
    cd00051
    Location:41904244
    EFh; EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to ...
    cd12877
    Location:652799
    SPRY1_RyR; SPRY domain 1 (SPRY1) of ryanodine receptor (RyR)
    cd12878
    Location:10781210
    SPRY2_RyR; SPRY domain 2 (SPRY2) of ryanodine receptor (RyR)
    cd12879
    Location:15421692
    SPRY3_RyR; SPRY domain 3 (SPRY3) of ryanodine receptor (RyR)
    pfam00520
    Location:48384980
    Ion_trans; Ion transport protein
    pfam01365
    Location:449646
    RYDR_ITPR; RIH domain
    pfam02026
    Location:853941
    RyR; RyR domain
    pfam02815
    Location:220399
    MIR; MIR domain
    pfam06459
    Location:45314711
    RR_TM4-6; Ryanodine Receptor TM 4-6
    pfam08454
    Location:39944107
    RIH_assoc; RyR and IP3R Homology associated
    cl19745
    Location:13209
    Ins145_P3_rec; Inositol 1,4,5-trisphosphate/ryanodine receptor
  2. NM_001356674.2NP_001343811.1  Uncharacterized protein CELE_K11C4.5 [Caenorhabditis elegans]

    Status: REVIEWED

    Conserved Domains (11) summary
    cd00051
    Location:41914245
    EFh; EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to ...
    cd12877
    Location:652799
    SPRY1_RyR; SPRY domain 1 (SPRY1) of ryanodine receptor (RyR)
    cd12878
    Location:10781210
    SPRY2_RyR; SPRY domain 2 (SPRY2) of ryanodine receptor (RyR)
    cd12879
    Location:15421692
    SPRY3_RyR; SPRY domain 3 (SPRY3) of ryanodine receptor (RyR)
    pfam00520
    Location:48394981
    Ion_trans; Ion transport protein
    pfam01365
    Location:449646
    RYDR_ITPR; RIH domain
    pfam02026
    Location:853941
    RyR; RyR domain
    pfam02815
    Location:220399
    MIR; MIR domain
    pfam06459
    Location:45324712
    RR_TM4-6; Ryanodine Receptor TM 4-6
    pfam08454
    Location:39954108
    RIH_assoc; RyR and IP3R Homology associated
    cl19745
    Location:13209
    Ins145_P3_rec; Inositol 1,4,5-trisphosphate/ryanodine receptor
  3. NM_001356675.2NP_001343689.1  Uncharacterized protein CELE_K11C4.5 [Caenorhabditis elegans]

    Status: REVIEWED

    Conserved Domains (11) summary
    cd00051
    Location:42044258
    EFh; EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to ...
    cd12877
    Location:652799
    SPRY1_RyR; SPRY domain 1 (SPRY1) of ryanodine receptor (RyR)
    cd12878
    Location:10781210
    SPRY2_RyR; SPRY domain 2 (SPRY2) of ryanodine receptor (RyR)
    cd12879
    Location:15421692
    SPRY3_RyR; SPRY domain 3 (SPRY3) of ryanodine receptor (RyR)
    pfam00520
    Location:48524994
    Ion_trans; Ion transport protein
    pfam01365
    Location:449646
    RYDR_ITPR; RIH domain
    pfam02026
    Location:853941
    RyR; RyR domain
    pfam02815
    Location:220399
    MIR; MIR domain
    pfam06459
    Location:45454725
    RR_TM4-6; Ryanodine Receptor TM 4-6
    pfam08454
    Location:40084121
    RIH_assoc; RyR and IP3R Homology associated
    cl19745
    Location:13209
    Ins145_P3_rec; Inositol 1,4,5-trisphosphate/ryanodine receptor
  4. NM_001356676.2NP_001343809.1  Uncharacterized protein CELE_K11C4.5 [Caenorhabditis elegans]

    Status: REVIEWED

    Conserved Domains (11) summary
    cd00051
    Location:42054259
    EFh; EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to ...
    cd12877
    Location:652799
    SPRY1_RyR; SPRY domain 1 (SPRY1) of ryanodine receptor (RyR)
    cd12878
    Location:10781210
    SPRY2_RyR; SPRY domain 2 (SPRY2) of ryanodine receptor (RyR)
    cd12879
    Location:15421692
    SPRY3_RyR; SPRY domain 3 (SPRY3) of ryanodine receptor (RyR)
    pfam00520
    Location:48534995
    Ion_trans; Ion transport protein
    pfam01365
    Location:449646
    RYDR_ITPR; RIH domain
    pfam02026
    Location:853941
    RyR; RyR domain
    pfam02815
    Location:220399
    MIR; MIR domain
    pfam06459
    Location:45464726
    RR_TM4-6; Ryanodine Receptor TM 4-6
    pfam08454
    Location:40094122
    RIH_assoc; RyR and IP3R Homology associated
    cl19745
    Location:13209
    Ins145_P3_rec; Inositol 1,4,5-trisphosphate/ryanodine receptor
  5. NM_001356677.2NP_001343695.1  Uncharacterized protein CELE_K11C4.5 [Caenorhabditis elegans]

    Status: REVIEWED

    Conserved Domains (11) summary
    cd00051
    Location:43064360
    EFh; EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to ...
    cd12877
    Location:652799
    SPRY1_RyR; SPRY domain 1 (SPRY1) of ryanodine receptor (RyR)
    cd12878
    Location:10781210
    SPRY2_RyR; SPRY domain 2 (SPRY2) of ryanodine receptor (RyR)
    cd12879
    Location:15421692
    SPRY3_RyR; SPRY domain 3 (SPRY3) of ryanodine receptor (RyR)
    pfam00520
    Location:49545096
    Ion_trans; Ion transport protein
    pfam01365
    Location:449646
    RYDR_ITPR; RIH domain
    pfam02026
    Location:853941
    RyR; RyR domain
    pfam02815
    Location:220399
    MIR; MIR domain
    pfam06459
    Location:46474827
    RR_TM4-6; Ryanodine Receptor TM 4-6
    pfam08454
    Location:41104223
    RIH_assoc; RyR and IP3R Homology associated
    cl19745
    Location:13209
    Ins145_P3_rec; Inositol 1,4,5-trisphosphate/ryanodine receptor
  6. NM_001356678.2NP_001343810.1  Uncharacterized protein CELE_K11C4.5 [Caenorhabditis elegans]

    Status: REVIEWED

    Conserved Domains (11) summary
    cd00051
    Location:43074361
    EFh; EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to ...
    cd12877
    Location:652799
    SPRY1_RyR; SPRY domain 1 (SPRY1) of ryanodine receptor (RyR)
    cd12878
    Location:10781210
    SPRY2_RyR; SPRY domain 2 (SPRY2) of ryanodine receptor (RyR)
    cd12879
    Location:15421692
    SPRY3_RyR; SPRY domain 3 (SPRY3) of ryanodine receptor (RyR)
    pfam00520
    Location:49555097
    Ion_trans; Ion transport protein
    pfam01365
    Location:449646
    RYDR_ITPR; RIH domain
    pfam02026
    Location:853941
    RyR; RyR domain
    pfam02815
    Location:220399
    MIR; MIR domain
    pfam06459
    Location:46484828
    RR_TM4-6; Ryanodine Receptor TM 4-6
    pfam08454
    Location:41114224
    RIH_assoc; RyR and IP3R Homology associated
    cl19745
    Location:13209
    Ins145_P3_rec; Inositol 1,4,5-trisphosphate/ryanodine receptor
  7. NM_001356679.2NP_001343688.1  Uncharacterized protein CELE_K11C4.5 [Caenorhabditis elegans]

    Status: REVIEWED

    Conserved Domains (11) summary
    cd00051
    Location:43204374
    EFh; EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to ...
    cd12877
    Location:652799
    SPRY1_RyR; SPRY domain 1 (SPRY1) of ryanodine receptor (RyR)
    cd12878
    Location:10781210
    SPRY2_RyR; SPRY domain 2 (SPRY2) of ryanodine receptor (RyR)
    cd12879
    Location:15421692
    SPRY3_RyR; SPRY domain 3 (SPRY3) of ryanodine receptor (RyR)
    pfam00520
    Location:49685110
    Ion_trans; Ion transport protein
    pfam01365
    Location:449646
    RYDR_ITPR; RIH domain
    pfam02026
    Location:853941
    RyR; RyR domain
    pfam02815
    Location:220399
    MIR; MIR domain
    pfam06459
    Location:46614841
    RR_TM4-6; Ryanodine Receptor TM 4-6
    pfam08454
    Location:41244237
    RIH_assoc; RyR and IP3R Homology associated
    cl19745
    Location:13209
    Ins145_P3_rec; Inositol 1,4,5-trisphosphate/ryanodine receptor
  8. NM_001356680.2NP_001343808.1  Uncharacterized protein CELE_K11C4.5 [Caenorhabditis elegans]

    Status: REVIEWED

    Conserved Domains (11) summary
    cd00051
    Location:43214375
    EFh; EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to ...
    cd12877
    Location:652799
    SPRY1_RyR; SPRY domain 1 (SPRY1) of ryanodine receptor (RyR)
    cd12878
    Location:10781210
    SPRY2_RyR; SPRY domain 2 (SPRY2) of ryanodine receptor (RyR)
    cd12879
    Location:15421692
    SPRY3_RyR; SPRY domain 3 (SPRY3) of ryanodine receptor (RyR)
    pfam00520
    Location:49695111
    Ion_trans; Ion transport protein
    pfam01365
    Location:449646
    RYDR_ITPR; RIH domain
    pfam02026
    Location:853941
    RyR; RyR domain
    pfam02815
    Location:220399
    MIR; MIR domain
    pfam06459
    Location:46624842
    RR_TM4-6; Ryanodine Receptor TM 4-6
    pfam08454
    Location:41254238
    RIH_assoc; RyR and IP3R Homology associated
    cl19745
    Location:13209
    Ins145_P3_rec; Inositol 1,4,5-trisphosphate/ryanodine receptor
  9. NM_001356681.2NP_001343815.1  Uncharacterized protein CELE_K11C4.5 [Caenorhabditis elegans]

    Status: REVIEWED

    Conserved Domains (11) summary
    cd00051
    Location:41884242
    EFh; EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to ...
    cd12877
    Location:650797
    SPRY1_RyR; SPRY domain 1 (SPRY1) of ryanodine receptor (RyR)
    cd12878
    Location:10761208
    SPRY2_RyR; SPRY domain 2 (SPRY2) of ryanodine receptor (RyR)
    cd12879
    Location:15401690
    SPRY3_RyR; SPRY domain 3 (SPRY3) of ryanodine receptor (RyR)
    pfam00520
    Location:48364978
    Ion_trans; Ion transport protein
    pfam01365
    Location:447644
    RYDR_ITPR; RIH domain
    pfam02026
    Location:851939
    RyR; RyR domain
    pfam02815
    Location:218397
    MIR; MIR domain
    pfam06459
    Location:45294709
    RR_TM4-6; Ryanodine Receptor TM 4-6
    pfam08454
    Location:39924105
    RIH_assoc; RyR and IP3R Homology associated
    cl19745
    Location:19207
    Ins145_P3_rec; Inositol 1,4,5-trisphosphate/ryanodine receptor
  10. NM_001356682.2NP_001343819.1  Uncharacterized protein CELE_K11C4.5 [Caenorhabditis elegans]

    Status: REVIEWED

    Conserved Domains (11) summary
    cd00051
    Location:41894243
    EFh; EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to ...
    cd12877
    Location:650797
    SPRY1_RyR; SPRY domain 1 (SPRY1) of ryanodine receptor (RyR)
    cd12878
    Location:10761208
    SPRY2_RyR; SPRY domain 2 (SPRY2) of ryanodine receptor (RyR)
    cd12879
    Location:15401690
    SPRY3_RyR; SPRY domain 3 (SPRY3) of ryanodine receptor (RyR)
    pfam00520
    Location:48374979
    Ion_trans; Ion transport protein
    pfam01365
    Location:447644
    RYDR_ITPR; RIH domain
    pfam02026
    Location:851939
    RyR; RyR domain
    pfam02815
    Location:218397
    MIR; MIR domain
    pfam06459
    Location:45304710
    RR_TM4-6; Ryanodine Receptor TM 4-6
    pfam08454
    Location:39934106
    RIH_assoc; RyR and IP3R Homology associated
    cl19745
    Location:19207
    Ins145_P3_rec; Inositol 1,4,5-trisphosphate/ryanodine receptor
  11. NM_001356683.2NP_001343813.1  Uncharacterized protein CELE_K11C4.5 [Caenorhabditis elegans]

    Status: REVIEWED

    Conserved Domains (11) summary
    cd00051
    Location:42024256
    EFh; EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to ...
    cd12877
    Location:650797
    SPRY1_RyR; SPRY domain 1 (SPRY1) of ryanodine receptor (RyR)
    cd12878
    Location:10761208
    SPRY2_RyR; SPRY domain 2 (SPRY2) of ryanodine receptor (RyR)
    cd12879
    Location:15401690
    SPRY3_RyR; SPRY domain 3 (SPRY3) of ryanodine receptor (RyR)
    pfam00520
    Location:48504992
    Ion_trans; Ion transport protein
    pfam01365
    Location:447644
    RYDR_ITPR; RIH domain
    pfam02026
    Location:851939
    RyR; RyR domain
    pfam02815
    Location:218397
    MIR; MIR domain
    pfam06459
    Location:45434723
    RR_TM4-6; Ryanodine Receptor TM 4-6
    pfam08454
    Location:40064119
    RIH_assoc; RyR and IP3R Homology associated
    cl19745
    Location:19207
    Ins145_P3_rec; Inositol 1,4,5-trisphosphate/ryanodine receptor
  12. NM_001356684.2NP_001343817.1  Uncharacterized protein CELE_K11C4.5 [Caenorhabditis elegans]

    Status: REVIEWED

    Conserved Domains (11) summary
    cd00051
    Location:42034257
    EFh; EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to ...
    cd12877
    Location:650797
    SPRY1_RyR; SPRY domain 1 (SPRY1) of ryanodine receptor (RyR)
    cd12878
    Location:10761208
    SPRY2_RyR; SPRY domain 2 (SPRY2) of ryanodine receptor (RyR)
    cd12879
    Location:15401690
    SPRY3_RyR; SPRY domain 3 (SPRY3) of ryanodine receptor (RyR)
    pfam00520
    Location:48514993
    Ion_trans; Ion transport protein
    pfam01365
    Location:447644
    RYDR_ITPR; RIH domain
    pfam02026
    Location:851939
    RyR; RyR domain
    pfam02815
    Location:218397
    MIR; MIR domain
    pfam06459
    Location:45444724
    RR_TM4-6; Ryanodine Receptor TM 4-6
    pfam08454
    Location:40074120
    RIH_assoc; RyR and IP3R Homology associated
    cl19745
    Location:19207
    Ins145_P3_rec; Inositol 1,4,5-trisphosphate/ryanodine receptor
  13. NM_001356685.2NP_001343814.1  Uncharacterized protein CELE_K11C4.5 [Caenorhabditis elegans]

    Status: REVIEWED

    Conserved Domains (11) summary
    cd00051
    Location:43044358
    EFh; EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to ...
    cd12877
    Location:650797
    SPRY1_RyR; SPRY domain 1 (SPRY1) of ryanodine receptor (RyR)
    cd12878
    Location:10761208
    SPRY2_RyR; SPRY domain 2 (SPRY2) of ryanodine receptor (RyR)
    cd12879
    Location:15401690
    SPRY3_RyR; SPRY domain 3 (SPRY3) of ryanodine receptor (RyR)
    pfam00520
    Location:49525094
    Ion_trans; Ion transport protein
    pfam01365
    Location:447644
    RYDR_ITPR; RIH domain
    pfam02026
    Location:851939
    RyR; RyR domain
    pfam02815
    Location:218397
    MIR; MIR domain
    pfam06459
    Location:46454825
    RR_TM4-6; Ryanodine Receptor TM 4-6
    pfam08454
    Location:41084221
    RIH_assoc; RyR and IP3R Homology associated
    cl19745
    Location:19207
    Ins145_P3_rec; Inositol 1,4,5-trisphosphate/ryanodine receptor
  14. NM_001356686.2NP_001343818.1  Uncharacterized protein CELE_K11C4.5 [Caenorhabditis elegans]

    Status: REVIEWED

    Conserved Domains (11) summary
    cd00051
    Location:43054359
    EFh; EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to ...
    cd12877
    Location:650797
    SPRY1_RyR; SPRY domain 1 (SPRY1) of ryanodine receptor (RyR)
    cd12878
    Location:10761208
    SPRY2_RyR; SPRY domain 2 (SPRY2) of ryanodine receptor (RyR)
    cd12879
    Location:15401690
    SPRY3_RyR; SPRY domain 3 (SPRY3) of ryanodine receptor (RyR)
    pfam00520
    Location:49535095
    Ion_trans; Ion transport protein
    pfam01365
    Location:447644
    RYDR_ITPR; RIH domain
    pfam02026
    Location:851939
    RyR; RyR domain
    pfam02815
    Location:218397
    MIR; MIR domain
    pfam06459
    Location:46464826
    RR_TM4-6; Ryanodine Receptor TM 4-6
    pfam08454
    Location:41094222
    RIH_assoc; RyR and IP3R Homology associated
    cl19745
    Location:19207
    Ins145_P3_rec; Inositol 1,4,5-trisphosphate/ryanodine receptor
  15. NM_001356687.2NP_001343812.1  Uncharacterized protein CELE_K11C4.5 [Caenorhabditis elegans]

    Status: REVIEWED

    Conserved Domains (11) summary
    cd00051
    Location:43184372
    EFh; EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to ...
    cd12877
    Location:650797
    SPRY1_RyR; SPRY domain 1 (SPRY1) of ryanodine receptor (RyR)
    cd12878
    Location:10761208
    SPRY2_RyR; SPRY domain 2 (SPRY2) of ryanodine receptor (RyR)
    cd12879
    Location:15401690
    SPRY3_RyR; SPRY domain 3 (SPRY3) of ryanodine receptor (RyR)
    pfam00520
    Location:49665108
    Ion_trans; Ion transport protein
    pfam01365
    Location:447644
    RYDR_ITPR; RIH domain
    pfam02026
    Location:851939
    RyR; RyR domain
    pfam02815
    Location:218397
    MIR; MIR domain
    pfam06459
    Location:46594839
    RR_TM4-6; Ryanodine Receptor TM 4-6
    pfam08454
    Location:41224235
    RIH_assoc; RyR and IP3R Homology associated
    cl19745
    Location:19207
    Ins145_P3_rec; Inositol 1,4,5-trisphosphate/ryanodine receptor
  16. NM_001356688.2NP_001343816.1  Uncharacterized protein CELE_K11C4.5 [Caenorhabditis elegans]

    Status: REVIEWED

    Conserved Domains (11) summary
    cd00051
    Location:43194373
    EFh; EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to ...
    cd12877
    Location:650797
    SPRY1_RyR; SPRY domain 1 (SPRY1) of ryanodine receptor (RyR)
    cd12878
    Location:10761208
    SPRY2_RyR; SPRY domain 2 (SPRY2) of ryanodine receptor (RyR)
    cd12879
    Location:15401690
    SPRY3_RyR; SPRY domain 3 (SPRY3) of ryanodine receptor (RyR)
    pfam00520
    Location:49675109
    Ion_trans; Ion transport protein
    pfam01365
    Location:447644
    RYDR_ITPR; RIH domain
    pfam02026
    Location:851939
    RyR; RyR domain
    pfam02815
    Location:218397
    MIR; MIR domain
    pfam06459
    Location:46604840
    RR_TM4-6; Ryanodine Receptor TM 4-6
    pfam08454
    Location:41234236
    RIH_assoc; RyR and IP3R Homology associated
    cl19745
    Location:19207
    Ins145_P3_rec; Inositol 1,4,5-trisphosphate/ryanodine receptor
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