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acl-6 Phospholipid/glycerol acyltransferase domain-containing protein;putative glycerol-3-phosphate acyltransferase, mitochondrial [ Caenorhabditis elegans ]

Gene ID: 178928, updated on 12-Jun-2024

Summary

Gene symbol
acl-6
Gene description
Phospholipid/glycerol acyltransferase domain-containing protein;putative glycerol-3-phosphate acyltransferase, mitochondrial
Locus tag
CELE_F08F3.2
See related
AllianceGenome:WB:WBGene00017261
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to enable glycerol-3-phosphate O-acyltransferase activity. Predicted to be involved in several processes, including glycerol-3-phosphate metabolic process; phospholipid biosynthetic process; and triglyceride biosynthetic process. Located in mitochondrion. Is expressed in muscle cell. Orthologous to several human genes including GPAM (glycerol-3-phosphate acyltransferase, mitochondrial). [provided by Alliance of Genome Resources, Apr 2022]
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Genomic context

See acl-6 in Genome Data Viewer
Location:
chromosome: V
Exon count:
12
Sequence:
Chromosome: V; NC_003283.11 (5433386..5437095)

Chromosome V - NC_003283.11Genomic Context describing neighboring genes Neighboring gene Ammonium transporter AmtB-like domain-containing protein Neighboring gene WSN domain-containing protein Neighboring gene SNAPc (Small Nuclear RNA Activating Complex) homolog Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
enables O-acyltransferase activity IEA
Inferred from Electronic Annotation
more info
 
enables acyltransferase activity IEA
Inferred from Electronic Annotation
more info
 
enables glycerol-3-phosphate O-acyltransferase activity IBA
Inferred from Biological aspect of Ancestor
more info
 
enables glycerol-3-phosphate O-acyltransferase activity IEA
Inferred from Electronic Annotation
more info
 
enables sn-1-glycerol-3-phosphate C16:0-DCA-CoA acyl transferase activity IEA
Inferred from Electronic Annotation
more info
 
enables transferase activity IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
involved_in CDP-diacylglycerol biosynthetic process IEA
Inferred from Electronic Annotation
more info
 
involved_in cellular lipid metabolic process IEA
Inferred from Electronic Annotation
more info
 
involved_in fatty acid metabolic process IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in glycerol-3-phosphate metabolic process IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in lipid metabolic process IEA
Inferred from Electronic Annotation
more info
 
involved_in phospholipid biosynthetic process IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in phospholipid biosynthetic process IEA
Inferred from Electronic Annotation
more info
 
involved_in triglyceride biosynthetic process IBA
Inferred from Biological aspect of Ancestor
more info
 
Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
 
is_active_in mitochondrial membrane IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in mitochondrial membrane IEA
Inferred from Electronic Annotation
more info
 
located_in mitochondrion IDA
Inferred from Direct Assay
more info
PubMed 
located_in mitochondrion IEA
Inferred from Electronic Annotation
more info
 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
Phospholipid/glycerol acyltransferase domain-containing protein;putative glycerol-3-phosphate acyltransferase, mitochondrial
NP_001023769.1
  • Confirmed by transcript evidence
NP_001023770.1
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003283.11 Reference assembly

    Range
    5433386..5437095
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001028599.5NP_001023770.1  Phospholipid/glycerol acyltransferase domain-containing protein [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_001023770.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    G8JY39
    Conserved Domains (2) summary
    cd07993
    Location:1190
    LPLAT_DHAPAT-like; Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: GPAT-like
    COG2937
    Location:2528
    PlsB; Glycerol-3-phosphate O-acyltransferase [Lipid transport and metabolism]
  2. NM_001028598.5NP_001023769.1  putative glycerol-3-phosphate acyltransferase, mitochondrial [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_001023769.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q22949
    Conserved Domains (2) summary
    cd07993
    Location:138350
    LPLAT_DHAPAT-like; Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: GPAT-like
    COG2937
    Location:58688
    PlsB; Glycerol-3-phosphate O-acyltransferase [Lipid transport and metabolism]