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unc-46 Lysosome-associated membrane glycoprotein 5 [ Caenorhabditis elegans ]

Gene ID: 178897, updated on 2-Nov-2024

Summary

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Official Symbol
unc-46
Official Full Name
Lysosome-associated membrane glycoprotein 5
Primary source
WormBase:WBGene00006782
Locus tag
CELE_C04F5.3
See related
AllianceGenome:WB:WBGene00006782
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Located in cytoplasmic vesicle and neuromuscular junction. Is expressed in GLR and neurons. [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See unc-46 in Genome Data Viewer
Location:
chromosome: V
Exon count:
7
Sequence:
Chromosome: V; NC_003283.11 (5097075..5099025, complement)

Chromosome V - NC_003283.11Genomic Context describing neighboring genes Neighboring gene Uncharacterized protein Neighboring gene ncRNA Neighboring gene Globin domain-containing protein Neighboring gene G protein-coupled receptor;Serpentine Receptor, class E (Epsilon) Neighboring gene G_PROTEIN_RECEP_F1_2 domain-containing protein Neighboring gene Serpentine Receptor, class AB (class A-like)

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003283.11

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Pairing for recombination in LGV of Caenorhabditis elegans: a model based on recombination in deficiency heterozygotes. Rosenbluth RE, et al. Genetics, 1990 Mar. PMID 2311918, Free PMC Article
  2. Photoaged microplastics induce neurotoxicity associated with damage to serotonergic, glutamatergic, dopaminergic, and GABAergic neuronal systems in Caenorhabditis elegans. Yu Y, et al. Sci Total Environ, 2023 Nov 20. PMID 37517734
  3. Spectrum of variations in dog-1/FANCJ and mdf-1/MAD1 defective Caenorhabditis elegans strains after long-term propagation. Tarailo-Graovac M, et al. BMC Genomics, 2015 Mar 18. PMID 25880765, Free PMC Article
  4. The maternal genes apx-1 and glp-1 and establishment of dorsal-ventral polarity in the early C. elegans embryo. Mello CC, et al. Cell, 1994 Apr 8. PMID 8156602
  5. Neurotoxicological evaluation of microcystin-LR exposure at environmental relevant concentrations on nematode Caenorhabditis elegans. Ju J, et al. Environ Sci Pollut Res Int, 2013 Mar. PMID 22956115

See all (38) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Gene Ontology Provided by WormBase

Component Evidence Code Pubs
located_in cytoplasmic vesicle IDA
Inferred from Direct Assay
more info
 PubMed 
located_in neuromuscular junction IDA
Inferred from Direct Assay
more info
 PubMed 

General protein information

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Preferred Names
Lysosome-associated membrane glycoprotein 5
NP_504365.1
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003283.11 Reference assembly

    Range
    5097075..5099025 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_071964.5 → NP_504365.1  Lysosome-associated membrane glycoprotein 5 [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_504365.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q9GZD5
Nucleotide Protein
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