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Mycs myc-like oncogene, s-myc protein [ Mus musculus (house mouse) ]

Gene ID: 17870, updated on 26-Sep-2022


Official Symbol
Mycsprovided by MGI
Official Full Name
myc-like oncogene, s-myc proteinprovided by MGI
Primary source
See related
Ensembl:ENSMUSG00000044597 AllianceGenome:MGI:1332242
Gene type
protein coding
RefSeq status
Mus musculus
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Predicted to enable DNA-binding transcription activator activity, RNA polymerase II-specific; RNA polymerase II cis-regulatory region sequence-specific DNA binding activity; and kinase binding activity. Predicted to be involved in negative regulation of gene expression; positive regulation of gene expression; and positive regulation of transcription by RNA polymerase II. Predicted to act upstream of or within apoptotic process. Predicted to be located in nucleolus and nucleoplasm. Is expressed in brain. Human ortholog(s) of this gene implicated in Feingold syndrome. Orthologous to human MYCN (MYCN proto-oncogene, bHLH transcription factor). [provided by Alliance of Genome Resources, Apr 2022]
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Genomic context

See Mycs in Genome Data Viewer
X A1.1; X 2.4 cM
Exon count:
Annotation release Status Assembly Chr Location
109 current GRCm39 (GCF_000001635.27) X NC_000086.8 (5378958..5381319, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) X NC_000086.7 (5466904..5469265, complement)

Chromosome X - NC_000086.8Genomic Context describing neighboring genes Neighboring gene predicted gene 9428 Neighboring gene predicted gene 5924 Neighboring gene developmental pluripotency associated 4 pseudogene Neighboring gene actin, beta pseudogene

Genomic regions, transcripts, and products

General gene information


Clone Names

  • MGC151451

Gene Ontology Provided by MGI

Component Evidence Code Pubs
located_in nucleolus ISO
Inferred from Sequence Orthology
more info
located_in nucleoplasm ISO
Inferred from Sequence Orthology
more info
located_in nucleus ISO
Inferred from Sequence Orthology
more info

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_010850.2NP_034980.2  protein S-Myc

    See identical proteins and their annotated locations for NP_034980.2

    Status: VALIDATED

    Source sequence(s)
    Consensus CDS
    Q3V0Z1, Q9Z304
    ENSMUSP00000054158.4, ENSMUST00000058404.5
    Conserved Domains (2) summary
    HLH; Helix-loop-helix domain, found in specific DNA- binding proteins that act as transcription factors; 60-100 amino acids long. A DNA-binding basic region is followed by two alpha-helices separated by a variable loop region; HLH forms homo- and heterodimers, ...
    Myc_N; Myc amino-terminal region

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J


  1. NC_000086.8 Reference GRCm39 C57BL/6J

    5378958..5381319 complement
    GenBank, FASTA, Sequence Viewer (Graphics)