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R09B5.11 Facilitated glucose transporter homolog [ Caenorhabditis elegans ]

Gene ID: 178634, updated on 4-Jan-2025

Summary

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Official Symbol
R09B5.11
Official Full Name
Facilitated glucose transporter homolog
Primary source
WormBase:WBGene00019979
Locus tag
CELE_R09B5.11
See related
AllianceGenome:WB:WBGene00019979
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to enable hexose transmembrane transporter activity. Predicted to be involved in monosaccharide transmembrane transport. Predicted to be located in plasma membrane. Predicted to be active in membrane. Is expressed in seam cell. Human ortholog(s) of this gene implicated in epilepsy (multiple); glucose metabolism disease (multiple); glycogen storage disease; myelomeningocele; and obesity. Orthologous to several human genes including SLC2A14 (solute carrier family 2 member 14) and SLC2A3 (solute carrier family 2 member 3). [provided by Alliance of Genome Resources, Jan 2025]
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Genomic context

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See R09B5.11 in Genome Data Viewer
Location:
chromosome: V
Exon count:
7
Sequence:
Chromosome: V; NC_003283.11 (1439205..1441867)

Chromosome V - NC_003283.11Genomic Context describing neighboring genes Neighboring gene Gut esterase 1 Neighboring gene pseudo Neighboring gene CaeNaCin (Caenorhabditis bacteriocin) Neighboring gene CaeNaCin (Caenorhabditis bacteriocin)

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003283.11

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
enables hexose transmembrane transporter activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables transmembrane transporter activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in hexose transmembrane transport IEA
Inferred from Electronic Annotation
more info
  
involved_in monosaccharide transmembrane transport IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in transmembrane transport IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
is_active_in membrane IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in membrane IEA
Inferred from Electronic Annotation
more info
  
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
Facilitated glucose transporter homolog
NP_503413.2
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003283.11 Reference assembly

    Range
    1439205..1441867
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_071012.8 → NP_503413.2  Facilitated glucose transporter homolog [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_503413.2

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    O44616
    Conserved Domains (2) summary
    cd06174
    Location:90 → 465
    MFS; The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of ...
    pfam00083
    Location:54 → 499
    Sugar_tr; Sugar (and other) transporter
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
O44616.2

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